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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Accurate, long read length, whole human genome sequencing under 100

    SBC: ELECTRONIC BIOSCIENCES, INC.            Topic: NHGRI

    DESCRIPTION (provided by applicant): The aim of this project is to investigate a simple method for slowing down the rate of electrophoretic translocation of DNA through a nanopore. Unique modulations of current across nanopores produced by individual basesduring such translocation forms the basis of DNA nanopore sequencing. The nanopore method requires very simple sample preparation with potential ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  2. A Clothing-Adhered Wearable to Monitor Biomarkers of Cognitive/Emotional State and Deliver Just-in-Time Behavioral Interventions

    SBC: Spire, Inc.            Topic: NIDA

    PROJECT SUMMARY Recovery from substance use disorders (SUDs) is greatly impacted by the cognitive and emotional state of the individual, and learning new thought and behavioral patterns can facilitate successful treatment and recovery. Specifically, fluctuations in stress or anxiety can trigger lapses to drug use. Even when actual use is avoided, stress-induced craving is likely to be distracting ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. A Comprehensive Fall Prevention System for Memory Care: Final Feasibility and Randomized Controlled Study

    SBC: SAFELYYOU INC.            Topic: NIA

    Abstract In the USAlzheimer s diseaseADis the single most expensive diseasethe only disease in the top six for which the number of deaths is increasingThe greatest cost contributors are frequent hospitalizationswhere falls are the largest culpritand frequent need for assistance with the activities of daily livingFall safety systems show the potential to reduce costs and increase quality of care by ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. A computational approach to early sepsis detection

    SBC: Dascena, Inc.            Topic: NCATS

    Abstract SignificanceIn this SBIR projectwe propose to improve the performance of InSighta machine learningbased sepsis screening systemin situations of limited training data from the target clinical siteThe proposed work will make possible prospective clinical deployments to sites which are smaller or lack clinical data repositoriesby significantly reducing the amount of training data necessary d ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. A cost-effective bioreactor to advance functional tissue engineering of cartilage

    SBC: Apex Biomedical Company, LLC            Topic: NIAMS

    DESCRIPTION (provided by applicant): Osteoarthritis (OA) is the leading cause of chronic disability in the United States. A clinical goal in the treatment and prevention of OA is to develop replacement cartilage using tissue engineering (TE) technologies. Although TE cartilage presently lacks the mechanical stability of native cartilage, studies have demonstrated that mechanical stability can be e ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  6. Activity of Fully Deleted Helper-Virus Independent Adenoviral Gene Therapy Vector

    SBC: ISOGENIS, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Numerous diseases are caused by gene defects. The goal of gene therapy is the effective treatment or cure of these diseases by the introduction of the normal gene or repair of the gene defect. A large research effort has been mounted to optimize gene transfer vectors mostly based on adenoviruses and retroviruses. Yet, the initial promise of gene therapy has bee ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  7. A Customizable Real-Time Biosensor for Continuous Monitoring of Water Contaminants

    SBC: QUANTITATIVE BIOSCIENCES, INC.            Topic: NIEHS

    Ensuring access to clean water for generations to come will involve developing novel approaches to determining the safety and composition of potable water that are practical and affordableArsenicmercuryand cadmium are three of the top priorities among hazardous substances commonly found at Superfund sitesas they are linked to health problems in people exposed to them in drinking wateryet the curre ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. A custom microchip amplifier for patch clamp electrophysiological recording

    SBC: MAINSTREAM ENGINEERING CORP            Topic: NIEHS

    DESCRIPTION: An estimated 2.5 billion people, or about one-third of the world's population, rely on biomass fuel for cooking. Emissions from biomass cook stoves contribute to global climate change, indoor/local air quality issues, and related health effects. In particular, indoor ir quality issues related to biomass cook stoves contribute significantly to rates of acute respiratory infection ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  9. ADAPT: After Deployment Adaptive Parenting Tools

    SBC: IRIS MEDIA INC            Topic: NICHD

    DESCRIPTION (provided by applicant): The goal of this project is to strengthen family functioning and improve child outcomes in military families after deployment. To achieve this end, we will develop, evaluate, and disseminate ADAPT: After Deployment: Adaptive Parenting Tools, an online, interactive resource for military parents. Significance: ADAPT responds to the urgent parenting needs of veter ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  10. Adapting the SISTA/SIHLE/WILLOW HIV Prevention Trilogy for Black Men Who Have Sex

    SBC: Sociometrics Corporation            Topic: NIMHD

    DESCRIPTION (provided by applicant): Black men who have sex with men (MSM) have been disproportionately affected by the HIV/AIDS epidemic in the United States. Yet, there are very few scientifically demonstrated effective HIV prevention interventions targeting Black MSM. This SBIR Phase I project will address this gap by creating an adaptation kit to support the delivery of the popular SISTA/SIHLE ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
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