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Award Data
The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Determination of optimal antisense oligonucleotide chemistry for efficient and safe splicing modulation in T cells
SBC: Autoimmunity Biologic Solutions, Inc. Topic: NIAIDPROJECT SUMMARY Multiple Sclerosis (MS) is the most common neurological disease of early adulthood and is mediated by autoimmune mechanisms that lead to demyelination and neuronal damage in the central nervous system, resulting in progressive neurological dysfunction. There is no cure for the disease and current treatments focus on preventing future immunological attacks, mainly by suppressing the ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
Non-Invasive Oropharynx Appliance to Maintain Airway Patency
SBC: ANEMED LLC Topic: NHLBIObstructive Sleep Apnea (OSA) is a serious condition that affects about 4% of the population. During sleep, the tongue can fall into the oropharynx and occlude the airways Patients with this condition suffer many instances of apneas (complete cessation of breathing) and hypopneas (period of abnormally low respiratory rate). The apnea- hypopnea index (AHI) gives the number of such episodes per hour ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
A small molecule integrin activator to enhance cord blood transplant
SBC: 7 Hills Pharma LLC Topic: NHLBIPROJECT SUMMARY This proposal is in response to the parent announcement for Phase II STTR (R42) grant applications. Hematopoietic stem cell transplantation has become a preferred treatment for hematological malignancies and certain genetic disorders. Umbilical cord blood has become an appealing alternative to bone marrow or peripheral blood as a source of hematopoietic stem cells for transplant. D ...
STTR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health -
Non-invasive Detection of Cerebral Aneurysm Recurrence after Endovascular Treatment Using Automated Image Processing
SBC: Medical Innovators Company, LLC Topic: 101PROJECT SUMMARY Hemorrhage due to cerebral aneurysm rupture is a devastating condition with high mortality. For the more than 30,000 patients in the US who are diagnosed annually with an aneurysm, treatment consists of preventing rupture, and increasingly relies of endovascular techniques. However, treatment durability is unknown with recurrence estimated at 16-40% and the re-treatment of 10-20%. ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
Multivalent Adjuvant Immunization to Prevent Hospital Acquired Infections
SBC: EXBAQ LLC Topic: NIAIDPROJECT SUMMARY According to the CDC, 550,000 Healthcare Associated Infections (HAIs) occur per year in the US, costing ~$100 billion and killing tens of thousands of patients. Reducing HAIs is a top priority of the US DHHS and NIH and experts have called for novel strategies including vaccination to achieve this goal.ExBaq was founded by scientists and business colleagues who have spent years stu ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
A Mobile/Web-based Training Curriculum for Disseminating Best Practices for the Care of Newborns with Neonatal Opioid Withdrawal Syndrome
SBC: OREGON RESEARCH BEHAVIORAL INTERVENTION STRATEGIES, INC. Topic: NIDAAbstractThe incidence of neonatal opioid withdrawal syndrome (NOWS) in the United States has grown dramatically over the past two decades. Efficient and effective resources and materials for training neonatal care providers in empirically based practices for NOWS are greatly needed. The goal of the proposed Phase I STTR project is to develop a highly accessible mobile/web-based multimedia curricul ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
Regenerative Therapy for Corneal Endothelial Dystrophies and Injuries
SBC: RASHMIVU LLC Topic: NSummary Worldwide, only 1 out of 70 patients with corneal endothelial dystrophies and injuries receive a corneal transplant due to the limited corneal donor pool, the need for advanced surgical facilities and talent, and expense. RashmiVu is developing a stem cell based regenerative technology that addresses this large unmet global need through a paradigm shift, wherein treatment could be as simpl ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
Integrated Platform for Mass-Spectrometric Studies of Protein Structure
SBC: PROTEIN METRICS INC Topic: 400Summary Technology for studying the higher order structure (HOS) and interactions of biomolecules is a highlighted NIGMS SBIR/STTR research topic. Mass-spectrometric methods for studying HOS include hydroxyl radical footprinting as well as chemical methods to covalently label amino acid side-chain functional groups, and also hydrogen/deuterium exchange (HDX) on protein backbone amides. These metho ...
STTR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health -
Pharmacological chaperones for the treatment of Open-Angle Glaucoma
SBC: Viewpoint Therapeutics, Inc. Topic: NEIOpen-angle glaucoma is the second leading cause of blindness worldwide, affecting nearly 70 million individuals. Nonsynonymous mutations in the myocilin gene lead to the most common hereditary form of open-angle glaucoma and account for 3-4% of all cases. Disease-causing mutations, localized to its olfactomedin domain (mOLF), destabilize the myocilin protein, leading to its misfolding and accumula ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
Portable, affordable, quantitative microchip electrophoresis system for integrated anemia and hemoglobin variant testing
SBC: HEMEX HEALTH INC Topic: NHLBIPROJECT SUMMARY Anemia is characterized by low blood hemoglobin levels and has high prevalence affecting over one-third of the worldandapos;s population or about 2.5 billion people. Anemia has numerous causes, including nutritional deficiencies, oncologic conditions, and hematologic diseases, including hemoglobin gene variants. More than 7% of the worldandapos;s population carry hemoglobin gene va ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health