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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Incorporating Bone Minerals into Orthopaedic Surfaces

    SBC: ADVANCED SURFACES AND PROCESSES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Submerged Electro-Spark Deposition (SESD, US patent pending), developed at Advanced Surfaces And Processes, Inc., is a surface modification technique. Any conductive surface can be modified with regards to surface texture and chemical composition. The objective of the present proposal is to use SESD to incorporate appreciable amounts of bone mineral elements, i ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  2. Morpholino Antisense Drugs for Hepatitis C Virus

    SBC: Avi Biopharma, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Hepatitis C Virus (HCV) causes a persistent infection in most humans exposed to the virus. HCV infection in time can lead to cirrhosis and hepatocellular carcinoma. Although the annual number of newly infected patients has dropped significantly over the past decade, about 4 million people are currently persistently infected in the USA. There is presently no un ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  3. Feasibility Evaluation of a Prosthetic Venous Value

    SBC: BIOMEDICAL RESEARCH ASSOCIATES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this Phase I STTR proposal is to demonstrate the feasibility of a novel prosthetic venous valve design concept. One of the ultimate goals in vascular surgery is to develop a successful prosthetic venous valve to replace defective valves in patients with chronic venous insufficiency (CVI). More than 8 million Americans suffer from the debilitating c ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  4. Cord Blood Cells in ALS: Replacement of Protection?

    SBC: SANERON CCEL THERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Amyotrophic lateral sclerosis (ALS) is a fatal degenerative disease affecting motor neurons in the spinal cord, brainstem and cortex. We have previously shown that transplanting neuronal cells into the spinal cord delays the onset of motor symptoms in the G93A mouse model of ALS, but developing a potential treatment strategy around a committed neuronal cell or ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  5. Development of new inhibitors of androgen receptors

    SBC: Cleveland Biolabs, Inc            Topic: N/A

    DESCRIPTION (provided by applicant): This program is aimed at developing a new class of drugs effective against most aggressive and a poorly curable hormone independent form of prostate cancer (CAP). Failure of androgen ablation therapy is rarely associated with the loss of the androgen receptor (AR) signaling by hormone-independent CaP. AR pathway in such tumors remains constitutively active rega ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  6. Assessing Suicide Risk in the ED: Web-based Education

    SBC: CME DEVELOPMENT GROUP, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Since the late 1980's there has been a sharp rise in the number of children and adolescents presenting to emergency departments (EDs) for psychiatric issues. Given that mental health issues account for 1.6% - 5.0% of all pediatric ED visits, and that Emergency Medical System's (EMS) staffs are the first to interact with these youth, the assessment of psychiatri ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  7. Thrombin Formation Inhibitors

    SBC: CURRAGH CHEMISTRIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Deep venous thrombosis (DVT) is a blood clot that has formed in one of the large veins far below the skin and blocks normal blood flow back to the heart. One of the major dangers of DVT is that part of the clot may break off and travel to the heart and lungs promoting a pulmonary embolism (PE). There are approximately 5 million cases of DVT per year in United S ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  8. Training for Treatment of Adolescent Depression

    SBC: DESCHUTES RESEARCH, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall aim of the proposed project is to develop an interactive computer-based program designed to train mental health professionals in use of an established cognitive-behavioral program for the treatment of adolescent depression. The Adolescent Coping With Depression (CWD-A) course has been empirically validated and adapted for a variety of formats (e.g., ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  9. User adjustable support surfaces for wheelchair comfort

    SBC: FALCON REHABILITATION PRODUCTS            Topic: N/A

    DESCRIPTION (provided by applicant): Individuals with disabilities who require the use of wheelchairs for all of their independent mobility often experience problems with chronic seat discomfort in their wheelchairs. In spite of this prevalent problem, very little research has been done and few products have been specifically developed to mitigate chronic wheelchair seat discomfort. Chronic wheel ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  10. Cytochlor/cytofluor: New Tumor Targeted Radiosensitizer

    SBC: HALOGENETICS            Topic: N/A

    DESCRIPTION (provided by applicant): Cytochlor Technology is about to enter a Phase I trial as a radiosensitizer of tumors of the oral cavity and oropharynx with NCI supervision. Our objective is to demonstrate Cytochlor's safety, selectivity and possible efficacy (although efficacy is not the goal of a Phase I trial). Our goal is to move Cytochlor Technology to a mutliinstitutional Phase II clini ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
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