Award Data

US military service members experiencing combated-related wounds have high chances of developing infection by multidrug resistant (MDR) bacteria. MDR infection results in higher amputation rate, subsequent operations and extended recovery time. Currently there is no FDA-cleared, deployable, rapid MDR bacteria testing assay. Optowares proposes to develop a RAPID (Rapid lAbel-free Pathogen Identific ...

Diagnosis of bacterial resistance in military deployment settings is challenging, representing a current health gap. Culture-based resistance testing is laborious, time consuming, and difficult to provide in resource-limited settings. We propose development of a precision metagenomics-based diagnostic tool by taking advantage of the rapid sequencing speed and portability of the Oxford Nanopore Min ...

Medical simulators emulate aspects of battlefield casualties and serve as effective aids to train soldiers and civilians for Tactical and Routine Combat Casualty Care. There is a need for more comprehensive and lifelike clinical simulated training than current sensors permit. Human-like simulator mannequins also require ease of use, a small footprint, little if any wiring, easy portability, and to ...

The greatest challenge with the protein therapeutic options in development for the treatment of COVID-19 is deployment. Currently these medicines require clinical infrastructure to deploy, are intravenously infused over hours, and have moderate to poor shelf-life stability. Elektrofi’s drug delivery technology (Elektroject™), coupled with these therapeutics could obviate, in many cases, the ne ...

Information regarding the state of Warfighters (e.g., fatigue, distraction, stress) and of the team (e.g., cohesion) can greatly impact mission planning and the likelihood of mission success. Harnessing neural data collected via functional near-infrared spectroscopy (fNIRS) can be a game-changing tool for assessing individual and team states, but current technologies do not support continuous neur ...

The fNIRS product is a non-invasive neuroimaging device that measures real-time changes in the concentration of oxygenated and de-oxygenated hemoglobin.  When sensors are placed at multiple places on the prefrontal cortex, the device measures changes blood oxygenation levels that can help determine various important parameters such as cognitive loading (amount of mental effort required to perform ...

81.1% of MEDEVAC in OIF/OEF were due to non-battle injury related injury with musculoskeletal injuries as leading cause. Many of these injuries will need to be managed in the operational environment without MEDEVAC. Future multi-domain battle operations against peer/near-peer adversaries will restrict MEDEVAC of injured warfighters necessitating care closer to the point of injury. Triton will deve ...

Advances such as mid-air refueling have extended mission profiles for naval aviation creating challenges for managing essential bodily functions such as waste elimination. Prolonged exposure of skin and mucous membranes to moisture can lead to growth of bacteria that can cause urinary tract infections and other medical issues. Triton Systems will continue the development of an undergarment that in ...

We propose to develop and test & evaluate an operational in-flight bladder relief undergarment to meet and/or exceed the key performance parameters (KPPs) per DHA193-003 solicitation. It is mission critical for air crew members to answer nature’s call with as little distraction as possible when he or she is in an unnaturally restricted position while concentrating on tasks at hands. Improper man ...

Hyperkalemia is a serious concern in the treatment of combat casualties as it is a common complication of acute kidney injury, which prevents the excretion of excessive plasma potassium released from damaged tissue. The risk of death from hyperkalemia-induced cardiac arrhythmias is significant in the absence of renal replacement therapy (RRT). Rapid evacuation out of Iraq and Afghanistan ensured t ...