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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. A CD8+ T cell diagnostic to identify children with pulmonary tuberculosis

    SBC: ViTi, Inc            Topic: NIAID

    DESCRIPTION provided by applicant Tuberculosis TB disease which results from infection with Mycobacterium tuberculosis Mtb is a leading cause of infectious morbidity and mortality in children andlt years old worldwide In TB endemic regions in which the vast majority of the worldandapos s annual million adult cases of TB disease reside children andlt years old account for ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  2. A Human Fc Bifunctional Fusion Protein to Treat Severe Allergic Asthma

    SBC: TUNITAS THERAPEUTICS, INC.            Topic: NIAID

    DESCRIPTION provided by applicant The overall goal of this phase SBIR proposal is to position our novel biologic GE for human clinical trials in allergic disease though the completion of critical preclinical development research activities GE a genetically engineered human fusion protein consisting of portions of the human gamma Fc linked to portions of the human epsilon Fc chain has unique mechan ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  3. An Auditory Evoked Response-Based Objective Tinnitus (AER-BOT) Diagnostic Device: Phase II

    SBC: Quantum Applied Science And Research, Inc.            Topic: OSD11H11

    In 2010 tinnitus became the most common service-related disability among veterans, with disability benefit costs projected to exceed $2.26 billion by 2014. Methods for objective diagnosis of tinnitus are currently nonexistent and direly needed by the military. QUASAR and Otosound are partnering on this SBIR project to develop an efficient and objective tinnitus diagnostic device. This device ...

    SBIR Phase II 2013 Department of DefenseDefense Health Program
  4. Apps for Rapid Epidemiological Analysis (AREA)

    SBC: PERCEPTRONICS SOLUTIONS, INC.            Topic: OSD11H17

    Managing basis health needs in HA/DR and STTR operations is of critical importance due to the increased risk of disease and health crises stemming from ecological changes, population displacement, population density changes, or the disruption of public utilities. Despite the critical needs for rapid epidemiological surveillance, assessment, and response in the field, very few technical aids e ...

    SBIR Phase II 2013 Department of DefenseDefense Health Program
  5. A research and drug development tool for the real time in vitro study of single c

    SBC: KYTARO, INC.            Topic: 100

    DESCRIPTION In this SBIR Phase II PicoCal will develop a high throughput apparatus to measure changes in cell adhesion at the level of individual receptor ligand interactions in real time This tool finds critical applications in research and drug development and would allow researchers to study and manipulate adhesion by bioactive compounds to promote or inhibit physiological processes There is a ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  6. A Universal Translator for Health Languages

    SBC: INFERLINK CORPORATION            Topic: DHP12004

    The potential to transform healthcare management through information technology continues to grow, as more systems, devices, and people than ever before provide and collect health data. Unfortunately, progress is slow because the multitude of systems to integrate do not speak a common language. We propose to create a universal translator between health languages, which will allow multiple system ...

    SBIR Phase I 2013 Department of DefenseDefense Health Program
  7. Bridging the Gap to Universal Health Information Exchange with Community-Driven Terminology Mediation

    SBC: Stottler Henke Associates, Inc.            Topic: DHP12004

    The most critical obstacle to the seamless exchange of healthcare information is the translation from the proprietary medical ontologies of private providers to a universal reference language (i.e., the 3M Health Data Dictionary). Stottler Henke proposes to develop a new system, called Bridge, which will directly address this challenge through three primary techniques. First, we employ a novel a ...

    SBIR Phase I 2013 Department of DefenseDefense Health Program
  8. Cell Lysates to Sequencing Reads: A Multiplex Gene Expression Profiling Tool for

    SBC: BioSpyder Technologies, Inc.            Topic: 172

    DESCRIPTION provided by applicant This proposed Phase I SBIR project will transfer RASL Seq a targeted sequencing technology developed in academia to a small business Xpress Inc and demonstrate feasibility for its commercialization as a platform for drug discovery and high throughput screening HTS The technology detects hundreds of RNA targets at once in cell lysates using oligo li ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  9. Cloud-Based Bioinformatics for Immune Repertoire Analysis

    SBC: Gigagen, Inc.            Topic: NHGRI

    DESCRIPTION provided by applicant The Specific Aim of this Phase II SBIR grant application is to launch ClonoByteandquot a website and cloud based platform for the processing storage analysis comparison and visualization of immune signature data sets generated by deep sequencing of immune repertoires There is a rapidly growing demand for T cell receptor TCR and immunoglobulin Ig repertoire sequenc ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  10. Commercialization of Magneto-Nanosensor Immunoassay Platform for Cancer Diagnosis

    SBC: Magarray, Inc.            Topic: 102

    DESCRIPTION provided by applicant This project seeks to optimize a promising magneto nanosensor technology for use in cancer diagnosis By adapting a common technology from the computer disk drive industry this simple device enables researchers to simultaneously detect multiple proteins or biomarkers at ultra low concentrations in biological fluids The abundance and change over time of seve ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
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