Award Data

Marburg virus (MARV) is a filamentous enveloped non-segmented negative sense RNA virus. This viruse is considered to be extremelydangerous with case fatality rates as high as 88-90%. Extensive efforts have gone towards effective vaccines for MARV prevention, however,none have been successfully established as licensed vaccines. Glycoprotein (GP) is the only surface protein of MARV. There are substa ...

Traumatic brain injury is a common problem in both the military and civilian communities, but current treatment protocols are focused on managing symptoms and fail to prevent significant long-term repercussions. In the proposed program, Luna will demonstrate the feasibility of a liposome-based therapeutic delivery system capable of delivering hydrophilic and hydrophobic therapeutics to the traumat ...

Traumatic brain injury (TBI) often occurs when a sudden trauma or head injury disrupts the function of the brain. Common causes of TBI include damage caused by explosive devices, falls and vehicle or motorcycle accidents. Sepsis is the result of a massive immune response to bacterial infection that gets into the blood. Sepsis often leads to organ failure or injury, and has always been a significan ...

This proposal is in response to the Defense Health Agency 2017 Phase I SBIR topic 17B-005.The approach is the use of a membrane oxygen pump using newly developed nano-thickness membranes with all the layers less than 1 micron total.Nanometer thickness membranes enable more oxygen output per surface area at temperatures of 300-600 C than current state-of-the -art 600-800 C membranes that are 50-300 ...

Clinicians have recognized that the nature of diseases can be highly individual resulting in different patterns of onset and progression. In turn, the response of an individual to drugs is also unique and governed by a variety of factors. Pharmacokinetic models represent the movement of a drug through the body, and personalized pharmacokinetic models aim to capture the unique responses of specific ...

Medical moulage is used in medical training to simulate injuries or pathologies, however current moulage is static and does not provide the trainee feedback on the quality of care or ultimate outcome of that care. Allowing a trainee to witness the injury or pathology -morph- while treatment is being provided can provide feedback on any potential mistreatment and enhance the learning and proficienc ...

Investments by the Department of Defense (DOD) have led to the development and demonstration of electronic textiles capable of transforming traditional textile systems into wearable power and data systems. The Defense Health Agency (DHA) has identified an opportunity to leverage advancements in smart garment systems for military personnel to aid in the prediction in performance declines and healt ...

Providing Army combat medics with meaningful experience in treatment of battlefield injuries is a particular challenge. Moulage has the potential to assist in acquiring what could otherwise be very hard-to-come-by preparatory experience for the distressing real-life emergencies medics and soldiers may encounter in the field. However, current approaches to moulage are limited in their ability to re ...

Recent advances in augmented reality (AR) offer valuable opportunities for simulationbased training outside of a medical simulator facility. The potential benefits for combat casualty care training are particularly powerful, as over 100,000 U.S. military medical personnel must be prepared to quickly respond to a broad range of injuries at any point in time. We propose to develop and evaluate a hig ...

Design Interactive Inc. (DI) and Eastern Virginia Medical School (EVMS) propose to develop an Augmented reality Learning Environment for Refresher Training (ALERT) that provides realistic and relevant Tactical Combat Casualty Care (TC3) scenarios using AR technologies integrated with mannequins for pre-deployment training and humans for deployed training environments. ALERT will facilitate learnin ...