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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A rapid high-throughput device to isolate antibiofilm bacteriophage

    SBC: GUILD ASSOCIATES INC            Topic: DHA20B003

    Multi-drug resistant (MDR) bacterial infections are a global public health crisis with ESKAPEE (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, Enterobacter spp, and Escherichia coli.) pathogens particularly troublesome. Wound infection is usually acquired in the hospital setting and is a significant source of morbidity and morta ...

    STTR Phase I 2021 Department of DefenseDefense Health Agency
  2. Brain Targeting Nanoparticle for Drug Delivery in Traumatic Brain Injury

    SBC: WEINBERG MEDICAL PHYSICS, INC.            Topic: DHA18A001

    There is an urgent need to bypass or cross the blood brain barrier (BBB) to deliver drugs for TBI treatment. This project aims to develop targted intranasally delivered, magnetically propulsed, and targted nanoparticles for traumatic brain injury (TBI). In Phase I, we will demonstrate the design, fabrication, and in vitro characterization of proposed drug laden magnetic nanoparticles as well as co ...

    STTR Phase I 2018 Department of DefenseDefense Health Agency
  3. Developing a Just-in-Time Refresher Trainer for Advanced Life Support in Austere Regions

    SBC: UNVEIL LLC            Topic: DHA20B001

    Early recognition of impending decompensation and appropriate intervention is critical to patient survival in many situations; yet, military personnel receive limited training about the early signs of decompensation through established training courses. Descriptions of respiratory distress, shock, and poor perfusion may be offered in training, but with little opportunity to practice recognizing th ...

    STTR Phase I 2021 Department of DefenseDefense Health Agency
  4. Energy & Power Dense Supercapacitor: On-Chip Integration in MEMs Fabrication

    SBC: MAINSTREAM ENGINEERING CORP            Topic: DMEA21A001

    Due to recent advances in the field of microelectronics, there is an increasing demand for micro-sized energy storage devices that are capable of being incorporated into and provide energy for MEMS devices. In order to continue to enable this technological growth, and the benefits that stem from it, the storage density of electrical energy must also continually be improved, especially with respect ...

    STTR Phase I 2021 Department of DefenseDefense Microelectronics Activity
  5. Fast Parameter Identification for Personalized Pharmacokinetics

    SBC: AUTONOMOUS HEALTHCARE INC            Topic: DHP17B003

    Drug dosingcan bemademore precise by using pharmacokineticand pharmacodynamicmodeling. Pharmacokinetics is thestudy of the concentration of drugs in tissueasafunction of timeand doseschedule,whereas pharmacodynamics is thestudy of therelationship between drugconcentration and drugeffect. By relating doseto resultant drugconcentration (pharmacokinetics)and concentration to effect (pharmacodynamics) ...

    STTR Phase I 2018 Department of DefenseDefense Health Agency
  6. Functionalized, Therapeutic-Loaded Liposomes for the Acute Treatment of TBI

    SBC: LUNA INNOVATIONS INCORPORATED            Topic: DHA18A001

    Traumatic brain injury is a common problem in both the military and civilian communities, but current treatment protocols are focused on managing symptoms and fail to prevent significant long-term repercussions. In the proposed program, Luna will demonstrate the feasibility of a liposome-based therapeutic delivery system capable of delivering hydrophilic and hydrophobic therapeutics to the traumat ...

    STTR Phase I 2018 Department of DefenseDefense Health Agency
  7. Graphenated Carbon Nanotube Based MEMS Supercapacitors

    SBC: Faraday Technology, Inc.            Topic: DMEA21A001

    The inherent advantages of MEMS technology, including small size and cost-effective fabrication, make it ideal for numerous application in a wide range of industries ranging from defense, automotive, medical, to consumer industries. For applications that require self-powered MEMS electronics, an integrated energy storage device is required. Due to their small size, excellent cycle life and high po ...

    STTR Phase I 2021 Department of DefenseDefense Microelectronics Activity
  8. Integrated Micro-Supercapacitors via Laser Induced Graphene from Photoresist

    SBC: CORNERSTONE RESEARCH GROUP INC            Topic: DMEA21A001

    While supercapacitors have been demonstrated for decades, the biggest challenge is to develop a reliable fabrication strategy which can integrate these devices with current CMOS (complementary metal oxide semiconductor) technology. Current fabrication technologies do not have good compatibility with other electronic components or cannot manufacture the supercapacitor in a small form factor. Conseq ...

    STTR Phase I 2021 Department of DefenseDefense Microelectronics Activity
  9. Oxygen Production and Delivery on Demand

    SBC: GLOBAL RESEARCH & DEVELOPMENT INC            Topic: DHA17B005

    This proposal is in response to the Defense Health Agency 2017 Phase I SBIR topic 17B-005.The approach is the use of a membrane oxygen pump using newly developed nano-thickness membranes with all the layers less than 1 micron total.Nanometer thickness membranes enable more oxygen output per surface area at temperatures of 300-600 C than current state-of-the -art 600-800 C membranes that are 50-300 ...

    STTR Phase I 2018 Department of DefenseDefense Health Agency
  10. Probabilistic Pharmacokinetic Models for Diagnosis, Prognosis, and Personalized Treatment

    SBC: BARRON ASSOCIATES, INC.            Topic: DHA17B003

    Clinicians have recognized that the nature of diseases can be highly individual resulting in different patterns of onset and progression. In turn, the response of an individual to drugs is also unique and governed by a variety of factors. Pharmacokinetic models represent the movement of a drug through the body, and personalized pharmacokinetic models aim to capture the unique responses of specific ...

    STTR Phase I 2018 Department of DefenseDefense Health Agency
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