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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A2A receptor blockade for sepsis

    SBC: Purine Pharmaceuticals Inc.            Topic: NIAID

    SUMMARY Sepsis is a clinical syndrome that complicates severe infectionSepsis remains the leading cause of morbidity and mortality in critically ill patientsThere are no specific FDA approved medicines for the treatment of sepsisCurrent concepts of the pathophysiology of sepsis suggest that organ failure and mortality in sepsis are caused by inappropriate regulation of the immune systemThis manife ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Accelerate Adoption of Galaxy Pro in the Biomedical Research Marketplace

    SBC: GalaxyWorks LLC            Topic: NHGRI

    Project Summary Galactic Core LLC aims to develop a robust, scalable, and managed service for performing enterprise-grade biomedical data analysis. The service will be based on the popular open-source Galaxy application (​https://galaxyproject.org/​), offering unlimited data storage and compute capabilities with an extremely powerful, flexible, and collaborative environment for analyzing data. ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Accelerating Site-specific Characterization of Protein Therapeutics with Novel Machine Learning Methods

    SBC: MASSMATRIX INC            Topic: 400

    PROJECT SUMMARYABSTRACT TitleAccelerating Site specific Characterization of Protein Therapeutics with Novel Machine Learning Methods The project seeks to improve reliability and speed up the development of life saving and life enhancingprecisionprotein therapeutics and magnify the positive impact of biomedical research and education worldwideleading to a quantum leap in our understanding of the mo ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Achieving Transformative Productivity through application of Collaborative Augmented Reality Systems (CARS)

    SBC: VECNA TECHNOLOGIES, INC            Topic: DLA181001

    The Defense Logistics Agency (DLA) is seeking to automate parts of their procurement, logistics, and distribution processes by applying Augmented Reality (AR) solutions to increase efficiency and reduce costs. Vecna Robotics' world-leading automation consulting team is well-positioned to leverage a deep and broad understanding of advanced technology and its application to warehouse operations. Vec ...

    SBIR Phase I 2018 Department of DefenseDefense Logistics Agency
  5. AC Impedance Sensor for Collective Protection Filter Residual Life Indicator

    SBC: GUILD ASSOCIATES INC            Topic: CBD10106

    Guild Associates, Inc. proposes to develop and evaluate an active electrochemical sensor based residual life indicator (RLI) for adsorptive carbon filters. The sensing system of the RLI will operate by analyzing the electrochemical state of the carbon within the filter and evaluate the remaining adsorptive reactive capacities of the filter. The sensor design will be challenged against an array of ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  6. AC5 Inhibitor for Obesity

    SBC: VASADE BIOSCIENCES, INC.            Topic: NIDDK

    DESCRIPTION (provided by applicant): The goal of this proposal is to develop a drug that will be therapeutic for obesity and diabetes and improve exercise tolerance. Obesity, diabetes and exercise are inextricably linked such that an agent that improves exercise tolerance or prevents obesity or the development of diabetes will likely have a therapeutic role in all three conditions. Obesity is a gl ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  7. A Clinical Trial Enrichment Tool Based on Subgroups Defined by Machine Learning Predictive Models

    SBC: ORIGENT DATA SCIENCES, INC.            Topic: 102

    ABSTRACT Neurodegenerative disordersincluding amyotrophic lateral sclerosisALSFriedreichandapos s ataxiaFAmultiple sclerosisMSDuchenne muscular dystrophyDMDAlzheimer s diseaseADParkinson s diseasePDand Huntington s diseaseHDare characterized by heterogeneous disease progressionEfforts to identify responder subgroups may uncover subgroups that are more homogeneous in disease related features than t ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. A Cloud-Based Web Application to Accelerate Targeted Covalent Drug Discovery

    SBC: COMPUTCHEM, LLC            Topic: 400

    Project Summary Abstract Covalent drug discovery is gaining increasing interest and clinical successespecially for cancer and infectious diseasesAlthough old covalent drugs were discovered serendipitouslymodern covalent drug discovery takes a rational approachWhile chemical intuition and trial and error are helpfulthe discovery process can be signi cantly shortened by the knowledge of whether the ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. A cloud-based WGS platform for establishing phylogeny within epidemic outbreaks at hospitals

    SBC: ICBiome            Topic: NIAID

    Outbreaks have become a significant public threat in hospitalsimpacting both patient lives and creating a financial burdenWith the increasing rise in antibiotic resistancenew interventions are urgently needed to contain ongoing outbreaksRecent studies have confirmed that whole genome sequencingWGSis able to identity unique mutations within each outbreak strainwhich can then be utilized to establis ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. A collaborative data collection and analysis for inquiry-based experiential learning for health sciences related STEM education

    SBC: WICKED DEVICE LLC            Topic: 500

    Abstract The U SDepartment of Commerce predicts that STEMsciencetechnologyengineeringand mathjobs occupations will grow byfromtocompared tofor non STEM occupationsSTEM wages are generally higher than non STEMwith adifference inYetcurrent approaches to STEM education are falling significantly shortInof U Shigh school students underwent American College TestingACTOf theseonlyattained the benchmark o ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
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