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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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A2A ADENOSINE AGONIST ADJUNCT FOR SYSTEMIC ANTHRAX
SBC: ADENOSINE THERAPEUTICS, LLC Topic: N/ADESCRIPTION (provided by applicant): This project develops A2A adenosine receptor (A2AAR) agonists as adjuncts to antibiotics for the treatment of anthrax septicemia. It responds to the urgent need for better treatment of highly lethal infections by this bioterrorism/biowarfare agent. Phase I has two aims, pharmaceutical development and documentation of efficacy in clinically relevant settings. Th ...
STTR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health -
A2A ADENOSINE AGONISTS LIMIT DAMAGE FROM INFECTION
SBC: ADENOSINE THERAPEUTICS, LLC Topic: N/Aepsis syndrome is the 11th leading cause of death in the United States ( about 900,000 new cases per year) with a mortality of about 35 percent. The need for adjunctive therapies is urgent. In Phase I of this SBIR award we documented the anti-inflammatory effects of adenosine A2A receptor (A2AAR) agonists on isolated immune cells and have observed ramatically improved survival in mouse models of I ...
STTR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health -
A cost-effective bioreactor to advance functional tissue engineering of cartilage
SBC: Apex Biomedical Company, LLC Topic: NIAMSDESCRIPTION (provided by applicant): Osteoarthritis (OA) is the leading cause of chronic disability in the United States. A clinical goal in the treatment and prevention of OA is to develop replacement cartilage using tissue engineering (TE) technologies. Although TE cartilage presently lacks the mechanical stability of native cartilage, studies have demonstrated that mechanical stability can be e ...
STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
A 3D Printed Resorbable Antimicrobial Envelope to Prevent Infection of Implanted Cardiac Devices
SBC: N8 MEDICAL INC Topic: NHLBIABSTRACT Infection is a serious and potentially fatal complication of surgery to deliver cardiovascular implantable electronic devicesCIEDsi epacemakers and implantable cardioverter defibrillatorsUntreated device related infection is associated with mortality rates as high asCurrentlyonly one antibiotic impregnated mesh has been FDA approved for placement in surgical incisions to reduce infections ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
A HOMOGENEOUS TRANSMIT COIL FOR HIGH FIELD HUMAN NMR
SBC: BIOENGINEERING, INC. Topic: N/ADESCRIPTION (provided by applicant): In this Phase II STTR project, the investigators plan to extend their successful Phase I feasibility demonstration to the development and manufacture of an RF body coil plus phased array receive system for use in high field clinical and research MRI systems. In Phase I, the feasibility of a large homogeneous transmit coil based on the TEM design was proven, pub ...
STTR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health -
AHTP-comet: development of an automated, high throughput comet assay system
SBC: ENGINEERING RESOURCES GROUP INC Topic: NIEHSPROJECT SUMMARY Genomic instabilityinduced by DNA damageand partly mitigated by DNA repair and antioxidantsplays a critical role in the pathogenesis of many major human diseasessuch as neurodegenerationcancer and cardiovascular diseasetogether with agingThere is a critical need for automated assays that can perform these assessmentsand bring them into greater routine usewhich will help advance our ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
An Advanced Lung Organomimetic to Reproduce Human Airway Pathophysiology
SBC: PNEUMAX, LLC Topic: 113PROJECT SUMMARYThree of top five causes of death in humans globally are lung relatedchronic obstructive pulmonary diseaseCOPDlower respiratory infections and lung cancers collectively account for over eight million deaths annuallyCurrentlyin preclinical settingstatic cell cultures and animal models are the most widely used systems for mechanistic and translational studiesHowevercritical limitation ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
A Novel remedy for periodontal bone loss
SBC: PERIOMICS CARE LLC Topic: NIDCRAbstract Periodontitis is a common chronic inflammatory disease characterized by destruction of the supporting structures of the teeththe periodontal ligament and alveolar boneThe total prevalence of periodontitis in adults agedyears and older wasrepresenting aboutmillion adults agedyears and olderandin adults agedyears and older in the U SEpidemiological data confirm that diabetes is a major risk ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
A novel RF coil and incubator for reducing acoustic noise in neonatal MRI
SBC: NeoView, Inc. Topic: NICHDPROJECT SUMMARY In this Phase I Small Business Technology TransferSTTRprojecta team of researchers at Cincinnati Childrenandapos s Hospital Medical CenterCCHMCwill work with the engineering team at NeoViewIncto design and build novel body coil and incubator prototypes for aTesla Neonatal Intensive Care UnitNICUMRI systemThese components will play a central role in NeoViewandapos s neonatal MRI pro ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
A NOVEL RF TENS DEVICE FOR ACUTE PAIN MANAGEMENT
SBC: CYCLOTEC ADVANCED MEDICAL TECHNOLOGIES Topic: N/ADESCRIPTION (provided by applicant): Cyclotec AMT, Inc. is developing 'non-invasive' transcutaneous electrical stimulators (TENS) that may prove to be viable adjuncts to or alternatives for drugs for management of recent onset "acute" pain. TENS has long been used for "chronic" pain management. The device complexities have made them prohibitive for short-term 'acute' applications; an application ...
STTR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health