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The Award database is continually updated throughout the year. As a result, data for FY21 is not expected to be complete until September, 2022.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Mobile Augmented Screening Tool to Increase Adolescent HIV Testing and Linkage to Care

    SBC: Digital Health Empowerment, Inc            Topic: NICHD

    ABSTRACTAdolescents face increased HIV riskinfrequent testinginconsistent linkage to careand a lack of prevention related knowledgeWe propose to address this by completing and evaluating the Mobile Augmented ScreeningMAStool to increase youth HIV testing via a tablet based intervention in clinical settingsand then use text messages to facilitate linkage to care for those who test positiveand deliv ...

    STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  2. A novel RF coil and incubator for reducing acoustic noise in neonatal MRI

    SBC: NeoView, Inc.            Topic: NICHD

    PROJECT SUMMARY In this Phase I Small Business Technology TransferSTTRprojecta team of researchers at Cincinnati Childrenandapos s Hospital Medical CenterCCHMCwill work with the engineering team at NeoViewIncto design and build novel body coil and incubator prototypes for aTesla Neonatal Intensive Care UnitNICUMRI systemThese components will play a central role in NeoViewandapos s neonatal MRI pro ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Validation of a salivary miRNA diagnostic test for autism spectrum disorder

    SBC: Quadrant Biosciences Inc.            Topic: 103

    Autism spectrum disorder (ASD) is a continuum of neurodevelopmental characteristics that includes deficits in communication and social interaction, as well as restrictive, repetitive interests and behaviors. ASD is an increasing public health concern, with about 1 in 45 American children diagnosed with ASD in 2014, a 10-fold increase in prevalence over the past 40 years. The effect of ASD on both ...

    STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Enhanced Software Tools for Detecting Anatomical Differences in Image Data Sets

    SBC: Kitware, Inc.            Topic: 105

    Project Summary Morphometric analysis is a primary algorithmic tool to discover disease and drug related effects on brain anatomy. Neurological degeneration and disease manifest in subtle and varied changes in brain anatomy that can be non-local in nature and effect amounts of white and gray matter as well as relative positioning and shapes of local brain anatomy. State-of-the-art morphometry meth ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Evaluation of a Novel Infection PET Diagnostic

    SBC: CHRONUS PHARMACEUTICALS, INC.            Topic: NIBIB

    Project Summary Abstract Bacterial infections such as those of prosthetic jointsbonesosteomyelitisand heart valvesinfective endocarditisare difficult to difficult to diagnose and treatand are a major cause of mortalitymorbidity and health care costsThe long term goal of our program is thus to develop positron emission tomographyPETradiotracers that can be used for non invasive PET imaging to detec ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Using advanced natural language processing to facilitate documentation of meaningful use and quality payment compliance

    SBC: Safermed, LLC            Topic: NLM

    PROJECT SUMMARY The Center for Medicare and Medicaid Services Quality Payment Program is designed to motivate healthcare providers to adhere to best practices in clinical healthcare and patient safetyUnfortunatelyextracting quality measures data from the clinical record is burdensome and as suchparticipation among clinical healthcare providers is suboptimalOur aim is to develop a system to facilit ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Development of Spleen Tyrosine Kinase (SYK) negative allosteric modifiers for therapeutic intervention in Alzheimer's disease.

    SBC: ARCHER PHARMACEUTICALS, INC.            Topic: NIA

    Pathological hallmarks of Alzheimerandapos s diseaseADinclude extracellular deposits of Apeptidesintraneuronal aggregates of abnormally phosphorylated tau protein and neuroinflammationMost proposed AD disease modifying therapies have focused on strategies that reduce brain Aamyloid or tau pathological accumulationHoweversuch approaches have been unsuccessful in late stage AD clinical trials and ma ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Making Standing Balance The Fifth Vital Sign in Clinical Settings

    SBC: Bertec Corporation            Topic: NIA

    Falls are a significant source of early morbidity and mortality in the aging populationyet the neurologicalsensoryand motor changes that lead to increased fall risk often escape early identification and interventionVital signs are commonly used in clinical settings to assess the cardiovascular systemblood pressureheart rateimmune systembody temperatureand the respiratory systemrespiratory rateto e ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Dressing Assistant: Home Technology to Sustain Independent Dressing in Dementia

    SBC: INVENTORS WORKSHOPS INC            Topic: NIA

    AbstractPersons living with dementiaPWDoften require assistance with routine activities and daily tasksWorkloads placed on caregivers often results in high levels of physical and emotional stressand depressionand higher overall morbidity and mortality ratesFocus group of caregivers for individuals with mild to moderate dementiaidentified dressing the PWD as the most pressing and stressful daily co ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Technology for the non-invasive surveilance of post-traumatic compartment syndrome

    SBC: Myolex Inc            Topic: NIAMS

    PROJECT SUMMARYAcute compartment syndromeACSremains one of the most devastating and often overlooked traumatic musculoskeletal disorders in clinical practiceIn this conditionpressure increases in one of the body s spacelimited compartmentsdue most commonly to direct trauma or bone fractureresulting ultimately in an ischemic injury to all of the compartment s contentsincluding muscle and nerveOnce ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
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