Award Data

The focus of this STTR phase I component is on proof-of-concept studies demonstrating applicability of technical approaches for identificationof circulatory diagnostic markers for infectious disease. Therefore, the primary objective of this project is to determine feasibility of one suchtechnical approach called Proteomics-based Expression Library Screening (PELS), for identification of pathogen-d ...

Marburg virus (MARV) is a filamentous enveloped non-segmented negative sense RNA virus. This viruse is considered to be extremelydangerous with case fatality rates as high as 88-90%. Extensive efforts have gone towards effective vaccines for MARV prevention, however,none have been successfully established as licensed vaccines. Glycoprotein (GP) is the only surface protein of MARV. There are substa ...

Reservoir Labs and Johns Hopkins University will develop alternative numerical solution techniques that improve computational loading, data storage, and data integrity for rocket vehicle trajectory modeling in MDA federated simulations.The objective of this program is to develop new techniques for trajectory propagation that are more suited for use in federated simulations than traditional methods ...

Metallic additive manufacturing (AM) is an attractive technology for the production of lethality test articles due to the potential for significantly reduced lead time and manufacturing cost.However, in order to be effective in providing accurate lethality data, the properties of the AM material have to match closely the properties of conventionally manufactured alloys found in real threat targets ...

The experimental validation of the DoDs weapon systems is at the cornerstone of national security considerations. The structural requirements for the targets utilized impose a severe cost and lead time burden due to the limitations imposed by the traditional manufacturing processes currently used. Novel manufacturing methods for metal alloys have been established in the past years, but they have y ...

Magnesium alloys have 35% lower density compared to aluminum, with improved temperature stability compared to high strength aluminum.They can also be fabricated with minimum gauge thicknesses considerably thinner than fiber composites, and are weldable, with much higher impact resistance.Traditional magnesium alloys, however, have had lower strengths than more developed aluminum alloys.Powder meta ...

Optonicus proposes development of the TAP-LAM (Test Article Printing with Laser Additive Manufacturing for Threat Surrogate Target Production) powder bed fusion and directed energy depositions systems. The TAP-LAM metal additive manufacturing system will advance strategic missile defense system testing capabilities by improving 3D printing methods to rapidly produce large-scale threat surrogate ta ...

The increasing penetration of MEMs devices into the commercial market has lead to an increasing demand for micro-sized electrical energy storage devices to interface with a support them. Electrochemical double layer capacitors hold significant promise as

The goal of this proposal is to demonstrate the feasibility of novel surface preparation methods that are easier to apply on metal substrates in various field environments while still enhancing the corrosion protective performance of topcoats. This is made possible by the characteristics of a patented pretreatment technology developed at Ecosil that can be spray or immersion applied. This novel ...

A significant cost and processing time reduction is realized by replacing the difficult manufacturing and machining processes associated with ceramic substrates, such as Silicon Carbide (SiC) or siliconized-SiC, with additive manufacturing or three dimensional (3D) printing. Along with reducing cost and time, additive manufacturing extends the capabilities of lightweight optics to meet more deman ...