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The Award database is continually updated throughout the year. As a result, data for FY21 is not expected to be complete until September, 2022.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. A High-Throughput Blood Esterase Panel Assay

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD10108

    Organophosphorus chemical warfare nerve agents (OP-CWA) are attractive to terrorist groups and rogue states as an inexpensive and accessible technology for chemical warfare. OP-CWA and organophosphate pesticides cause severe neurological symptoms and death by inhibiting the enzyme acetylcholinesterase (AChE); the resulting excess acetylcholine accumulates and overstimulates the human or animal bo ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  2. Rapid, Non-Thermally Cured Composite Fabrication

    SBC: Luna Innovations Incorporated            Topic: DLA09001

    Composite materials, with their high strength to weight ratios, manipulative properties, and corrosion resistance are now widely utilized throughout the military. High performance composites are required for air, sea, and land platforms. One of the drawbacks of these composite systems is the excessive costs and time required for part manufacturing. Prolonged elevated temperature curing is typic ...

    SBIR Phase I 2010 Department of DefenseDefense Logistics Agency
  3. Low/No Power Detector for Organophosphate Nerve Agents

    SBC: Luna Innovations Incorporated            Topic: CBD10101

    Organophosphate (OP) nerve agents are the most dangerous chemical warfare agents and therefore pose a significant threat. Rapid and exact identification of the OP agent involved in any hazardous material incident could significantly facilitate the administration of the most effective therapeutic and allow for appropriate measures of protection and decontamination, thereby increasing survival of t ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  4. AC Impedance Sensor for Collective Protection Filter Residual Life Indicator

    SBC: Guild Associates, Inc.            Topic: CBD10106

    Guild Associates, Inc. proposes to develop and evaluate an active electrochemical sensor based residual life indicator (RLI) for adsorptive carbon filters. The sensing system of the RLI will operate by analyzing the electrochemical state of the carbon within the filter and evaluate the remaining adsorptive reactive capacities of the filter. The sensor design will be challenged against an array of ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  5. Residual Life Indicator for Adsorptive and Reactive Single-Pass Filtration Systems

    SBC: MORPHIX TECHNOLOGIES, INC.            Topic: CBD10106

    In peacetime environments, concerns over improbable encounter with agent threats are supplanted by the need to understand and assess the performance status or residual life (RL) capacity of sorbent-based technologies used in Collective Protection (ColPro) systems. Systems such as the M98 and M48A1 run continuously and therefore sample large volumes of outside air over their lifetime. It is well- ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  6. In vitro Models Suitable for High-throughput Screening of Drug Toxicities in Human Tissues

    SBC: Nico Technologies Corp.            Topic: CBD10103

    The drug R&D cycle is long and very expensive. In many ways, this status quo can no longer be sustained. One of the reasons for such great cost is that the vast majority of drug candidates are screened out at the stages of animal and human trials. More efficient methods of testing of drugs at the stage of ex-vivo studies, which are substantially less expensive than animal and human testing cyc ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  7. Machine Diagnostics System on a Chip

    SBC: ORBITAL RESEARCH INC            Topic: DMEA102001

    The diagnostic systems in use in military machines are large and expensive. Other military machines could benefit from diagnostic and prognostic systems, but cannot afford the added size, weight and expense. Orbital Research proposes to address this issue by adapting the rugged ASICs that it has presently in development, and those planned for future development, into a single System on a Chip ( ...

    SBIR Phase I 2010 Department of DefenseDefense Microelectronics Activity
  8. DEVELOPMENT OF A BIOSENSOR NANOFLUIDIC PLATFORM FOR INTEGRATION WITH TERAHERTZ SPECTROSCOPIC SYSTEM

    SBC: VIBRATESS            Topic: CBD10110

    The goal of this SBIR project is to develop and demonstrate an electrokinetically driven nanofluidic sensor device of the physical size and shape that will allow integration with a THz spectroscopic instrument. The substrate and channel surfaces within the device will be appropriate for the acquisition of THz-frequency spectroscopic features from bio-molecules (e.g., DNA, RNA, proteins) in soluti ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  9. Affinity Matrix System for Large-Scale Protein Purification

    SBC: Luna Innovations Incorporated            Topic: CBD12102

    Though vast improvements have been made in various protein expression platforms, limitations arise in the implementation of current purification methods. Traditional chromatographic methods are time intensive, carry heavy material costs, and are difficult to scale - reducing the benefits achieved in protein expression. Affinity-binding methods are promising for scale-up and swiftness of purificati ...

    SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
  10. Microhydrogel Depot for Sustained Delivery of Prophylactic Bioscavenger

    SBC: Luna Innovations Incorporated            Topic: CBD13107

    Neurotoxic organophosphorus (OP) agents (e.g. sarin, soman, VX and tabun) were developed initially as pesticides and adapted for chemical warfare. OP agents are fast acting and lethal at even very low doses. Countering the threat of intoxication by OP nerve agents is an important mission for homeland security. Currently, the most promising strategy to counter OP intoxication is to scavenge the age ...

    SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
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