Award Data

INTRODUCTION: PRESENT BLOOD GAS AND ELECTROLYTE INSTRUMENTATION IS DESIGNED PRIMARILY FOR HOSPITAL USE. A FIELD UNIT MUST BE PORTABLE, TECHNICALLY EASY TO OPERATE, AND BE OPERATIONAL ALMOST IMMEDIATELY AFTER BEING TAKEN FROMSTORAGE OR HAVING BEEN TRANSPORTED. PROJECTED OBJECTIVE: THE PURPOSE OF THIS PROPOSAL IS TO DEVELOP A PROTOTYPE FIELDLABORATORY FOR MEASUREMENT OF BLOOD PO2, PCO2, PH, HCO 3, K ...

CARDIOPULMONARY BYPASS (CPB) ARE MADE ON DISCRETE BLOOD SAMPLES DRAWN AT VARIOUS INTERVALS. ALTHOUGH THIS IS USUALLY SUFFICIENT, IT IS NOT ADEQUATE DURING AN ACUTE CRISIS. IT IS ALSO HIGHLY PROBABLE, PARTICULARLY IN OLDER PATIENTS, PATIENTS WITH MULTIORGAN DYSFUNCTION, AND POSSIBLYEVEN PATIENTS WITHOUT OTHER COMPLICATIONS, THAT RECOVERY TIME WILL BE LESS EVENTFUL WITH MORE PRECISE MONITORING OF BL ...

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SELECTIVE EXPOSURE RADIOGRAPHY IS A TECHNIQUE IN WHICH A PATIENT-SPECIFIC DIGITAL-BEAM ATTENUATOR (DBA) IS PLACED BEFORE THE PATIENT TO OPTIMIZE THE DISTRIBUTION OF INCIDENT RADIATION. THE FILTER IS FABRICATED BY A PRINTER EQUIPPED WITH A CERIUM RIBBON. THE FILTER IS BASED ON TEST SHOT INFORMATION DIGITIZED FROM THE OUTPUT OF A DETECTOR BEHIND THE PATIENT. THE TECHNIQUE IS BEING DEVELOPED AT THE U ...

GENERATION OF MAGNETIC RESONANCE IMAGES OF INTRACRANIAL AND EXTRACRANIAL CAROTID ARTERIAL LUMENS, TOGETHER WITH RELATED VOLUME BLOOD FLOW INFORMATION FOR EACH LUMEN, HAS POTENTIAL FOR PROVIDING A NONINVASIVE AND MORE DEFINITIVE TECHNIQUE FOR DIAGNOSIS OF INCIPIENT STROKE DUE TO ARTERIAL DISEASE THAN EITHER ULTRASOUND OR ANGIOGRAPHY. TO DEMONSTRATE THIS POTENTIAL, WE PROPOSE TO APPLY A SENSITIVE LI ...

THE APPLICATION OF ORGANIC SEMICONDUCTOR MATERIALS AS THIN FILM LIGHT EMITTERS IS STUDIED. THE MATERIALS EXAMINED ARE THE METAL PHTHALOCYANINES AND CHEMICALLY DOPED VARIATIONS. THEY ARE DEPOSITED ON CONTROLLED SUBSTRATES BY AN ULTRAHIGH VACUUM MOLECULAR BEAM EXPITAXY APPROACH TO ENHANCE FILM CRYSTAL GROWTH IN A PLANARSTACKED RING MOLECULAR ORIENTATION THAT IS EXPECTED TO GIVE PROPERTIES DIFFERENT ...

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WE PROPOSE TO DEVELOP A COMPUTER SYSTEM FOR THE ELDERLY TO HELP MAINTAIN AND ENHANCE MEMORY CAPABILITIES. THE SYSTEM WILL USE THE FRAMEWORK OF REALITY ORIENTATION, I.E., STIMULATION AND REPETITIVE ORIENTATION TO TIME, PLACE, PERSON, AND DAILY ACTIVITIES, WITH FREQUENT ENCOURAGEMENT AND REWARD. THE FOCUS OF THE MATERIAL COVERED WILL BE ACTIVITIES OF DAILY LIVING. THE PURPOSE OF THIS SYSTEM IS TO HE ...

TECHNIQUE FOR RESOLVING COMPLEX MIXTURES OF PROTEINS. HOWEVER, THE METHOD HAS HAD LITTLE CLINICAL USE BECAUSE IT IS NOT QUANTITATIVE. THE WORK PROPOSED HERE IS DIRECTED TOWARD CAREFUL QUANTITATION, USING 2-D ELECTROPHORESIS, OF 6 TEST SERUM PROTEINS WHICH CAN BE PURCHASED AND ARE WELL RESOLVED ON A 2-D GEL. THE PROTEINS ALBUMIN, TRANSFERRIN, ALPHA-ANTITRYPSIN, APO-AL LIPOPROTEIN, IGG HEAVY CHAIN A ...