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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Automated Synthesis of Large DNA Fragments

    SBC: BLUE HERON BIOTECHNOLOGY, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term objective of this research is to provide researchers with fast, inexpensive access to any DNA sequence. Gene-based research is at the heart of drug discovery today. The ability to acquire and modify genes is integral to much of the basic research supported by the NIH; research which will be the foundation of future therapeutic research. Fast and c ...

    SBIR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  2. Piezoelectric Pipetting Technology for DNA Analysis

    SBC: ENGINEERING ARTS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The proposed research follows two distinct yet complementary paths. One path involves developing and testing novel piezoelectric pipetting, dispensing, sensing and housing technology and integrating this into a fully automated piezoelectric pipetting system. Innovative piezoelectric-based technology enables pipetting of sub-nanoliter volumes of fluid and contin ...

    SBIR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  3. Simulation Environment in Support of Non-Cooperative Target Recognition (NCTR) Algorithm Development

    SBC: DIGITAL SYSTEM RESOURCES, INC.            Topic: N/A

    A software based simulation environment for stimulation of developmental NCTR algorithms is proposed. The proposed software will consist of a distributed architecture simulation, interconnected via a standard network protocol LAN. This simulation willinclude 3-degree of motion (3DOF) models of both surface ship and airborne surveillance platforms equipped with a modern volume search radar, a multi ...

    SBIR Phase II 2003 Department of DefenseNavy
  4. Next Generation eRA: Portable Internet Date Containers

    SBC: FORMATTA CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): Research is proposed to improve and extend an existing, successful, commercial electronic forms product line whereby documents can be filled out either online or offline, electronically signed and then securely transmitted over the Internet. A system based upon this technology would allow research institutions to utilize FREE, Internet downloadable software to ...

    SBIR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  5. Autologous T Cell Therapy for CLL

    SBC: XCYTE THERAPIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Xcyte Therapies has developed a process ("Xcellerate") for the ex vivo activation and expansion of T cells using magnetic beads coated with antibodies to CD3 and CD28. Xcellerated T Cells from patients with CLL demonstrate an enhanced T cell repertoire, and the ability to induce the apoptosis of autologous tumor cells. Xcyte Therapies now plans to test this pro ...

    SBIR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  6. The Sentinel Event Tracking Network(SETNET)System

    SBC: CEREPLEX            Topic: N/A

    DESCRIPTION (provided by applicant): Hospital-acquired infections, antimicrobial use, and antimicrobial resistance are complex and inter-related problems, responsible for high health and financial costs, that every hospital faces. Cereplex, Inc. is developing its internet-based Sentinel Event Tracking Network (SETNET) application to fulfill hospitals' unmet needs in this area. In Phase 1 SETNET ...

    SBIR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  7. Target Validation using Gene Knockouts in Somatic Cells

    SBC: PANGENEX, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Many human diseases, including cancers, have inadequate medical treatments. Often, inadequacy is not due to poor drug quality, but rather to limitations associated with the target of the drug (e.g. inadequate efficacy or unacceptable toxicity). New drug targets are therefore required to address these unmet medical needs. The availability of complete drafts of t ...

    SBIR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  8. Polymer-Based Yersinia Pestis Point-of-Case Diagnostics

    SBC: Nomadics, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of the proposed research is to develop a highly sensitive and specific multi-locus array diagnostic for rapid identification of Yersinia pestis, the causative agent of plague. This infectious bacterial agent is on the NIAID category A priority list as a potential biological warfare (BW) agent. In order to confirm suspicions that clinical cases may be d ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  9. Magnetorheological Fluids based Isolators for Spacecraft and Missile Components

    SBC: MATERIALS MODIFICATIONS INC            Topic: N/A

    Loss of Line of Sight (LOS) due to low and high frequency vibrations in fast maneuvering THAAD missiles can result in catastrophic mission failure. The ability to hit a Re-Entry Vehicle (RV) carrying a nuclear/biological/chemical warhead either in themid-course of the terminal phase, is directly related to the capability of the sensor to maintain an accurate LOS to assure an accurate hit-to-kill b ...

    SBIR Phase II 2003 Department of DefenseMissile Defense Agency
  10. Novel agonists and antogonists of chemokine receptors

    SBC: ICOGENEX CORPORATION            Topic: N/A

    DESCRIPTION (provided by the applicant): A key event in the initiation and maintenance of an inflammatory response is the recruitment of immune effector cells to the site of a local immune response. This recruitment and retention is mediated by chemoattractant compounds, of which chemokines are an essential component. The chemokine family consists of ~50 small proteins, which mediate effects thro ...

    SBIR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
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