Award Data

NON-TECHNICAL SUMMARY: This is a phase I SBIR proposal by Adenosine Therapeutics for 6 months of support to synthesize and evaluate novel compounds as agonists of equine A2A adenosine receptors. Some of these compounds have been found to be very effective in reducing rodent mortality form endotoxin or from E. coli-induced sepsis. Circulating endotoxin (lipopolysaccharide) is correlated with the pr ...

A high-fidelity RF/Analog fiber-optic link based on a balanced photodetection using a dual-output modulator and a balanced photodetector pair offers significant improvement in RF gain, low noise figure (NF) and enhanced spur-free dynamic range (SFDR). It requires the use of path-length matched dual fibers to achieve proper noise cancellation. The objective for this SBIR is to develop a balanced fi ...

The structure of the electric utility business has long been a centralized model where an electric utility is the only authority selling electricity to, and buying excess rooftop PV generation, from customers. This is changing as utilities explore new business models including Distributed System Operator (DSO) models. On the other side of the meter, with the increasing penetration of rooftop solar ...

TECHNICAL ABSTRACT: Animal-borne electronic instruments (tags) are critical tools for monitoring the behavior and ecology of cetaceans, providing data needed for managing their populations and mitigating the threats they face. Although remote-deployment of tags onto cetaceans that cannot be captured has provided valuable data, attachment durations have been frustratingly short and variable. Our Ph ...

The gas turbine engine in the Army Abrams tank, the Honeywell AGT-1500, is currently experiencing stall and surge related failures of the fourth stage Low Pressure Compressor (LPC). These failures require the removal and overhaul of the tank’s powerpack costing the Army up to $200,000 per event. While all gas turbine compressors run the risk of stalling under non-ideal inlet or operational condi ...

The primary goals of the Phase I research plan are to develop a prototype absorbable stent for use in mid-tubal reanastomosis and to evaluate the effectiveness of this device in a rabbit experimental model. Mechanical design criteria will be determined by making measurements of luminal caliber and tubal compliance in freshly excised rabbit oviducts. The stent will be designed to 1) accommodate dis ...

DESCRIPTION (provided by applicant): The major objective of the proposed project is to develop methodology that will allow fast and efficient detection of infectious prion proteins prior to the onset of clinical symptoms. This includes the detection of infectious prions in mortal products, early ante-mortem diagnostic of the prion diseases, and developing experimental approaches allowing deline ...

The feasibility of a new approach that will accelerate the modeling of problems involving rarefied gas dynamics is established. The proposed hybrid approach solves the Boltzmann equation directly using a carefully designed discrete-velocity model and adiscrete Monte Carlo collision process with several extensions that accelerates its computational capability in comparison with direct simulation M ...

DESCRIPTION (provided by applicant): Many high schools use a graphing scientific calculator to assist students in math and science courses. These calculators have a built-in screen and displays graphs and perform scientific functions. These calculators are used widely in higher math (Algebra I and beyond) and science courses. They are a valuable tool for high school teachers and students. Unfor ...

DESCRIPTION (provided by applicant): Many high schools use a graphing scientific calculator to assist students in math and science courses. These calculators have a built-in screen and displays graphs and perform scientific functions. These calculators are used widely in higher math (Algebra I and beyond) and science courses. They are a valuable tool for high school teachers and students. Unfor ...