Award Data

Glucose abnormalities significantly affect patient morbidity and mortality. Currently, glycemic control is achieved via medications and exogenous insulin regimens that are costly both in terms of qualified personnel and consumables. Furthermore, none of these approaches are curative. Strategies under development such artificial pancreases do not necessarily address these limitations because they w ...

Autonomous underwater vehicles (AUVs) are critical to DoD undersea missions including the future capabilities for sea and sub-sea forces communication and connectivity. AUV mission lengths are currently limited to 24 hours due to the prohibitive battery storage and AUV energy demands. Makai Ocean Engineering, with the University of Hawaii’s Hawaii Natural Energy Institute (HNEI), proposes to dev ...

Methods for interconversion between cell types (cellular reprogramming) are currently discovered through resource intensive trial and error. Experiments may test a multitude of transcription factors to identify correct combinations that influence cell fate. In addition, reprogramming approaches commonly use stem cell intermediates such as induced pluripotent stem cells (iPSCs), which are generated ...

Traumatic injuries account for 30% of all life years lost in the US and is the leading cause of death for people under 46 years of age. Uncontrolled bleeding or hemorrhage constitute 30-40% of trauma related deaths and are considered to be a major cause o

Terrorist use of radioactive nuclear materials via nuclear and/or radiological dispersion devices (dirty bombs) is a serious threat. Therefore, it is crucial to detect proliferation of nuclear material. Critical challenges include: (a) high sensitivity detection of signature emissions from radioactive isotopes, and (b) cost-effectiveness for deployment of sensor networks across large storage facil ...

High G Aerodynamic Controls | Approved for Public Release 18-MDA-9707 (3 Jul 18)

Development of novel propulsion systems in the past two decades has focused almost exclusively on cryogenic boost-phase systems (LOX/LH2, LOX/LCH4, and LOX/RP-1) for launchers and uppers stage engines, and Attitude / Reaction Control Systems (A/RCS) for in-space applications using green monopropellants such AF-M315E or LMP-103S. Basic research and development of scalable, non-toxic, non-cryogenic, ...

Uncertainty Reduction in High Speed Flight Vehicle Modeling | Approved for Public Release 18-MDA-9707 (3 Jul 18)

Uncertainty Reduction in High Speed Flight Vehicle Modeling | Approved for Public Release 18-MDA-9707 (3 Jul 18)

Uncertainty Reduction in High Speed Flight Vehicle Modeling | Approved for Public Release 18-MDA-9707 (3 Jul 18)