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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. AC5 Inhibitor for Obesity

    SBC: VASADE BIOSCIENCES, INC.            Topic: NIDDK

    DESCRIPTION (provided by applicant): The goal of this proposal is to develop a drug that will be therapeutic for obesity and diabetes and improve exercise tolerance. Obesity, diabetes and exercise are inextricably linked such that an agent that improves exercise tolerance or prevents obesity or the development of diabetes will likely have a therapeutic role in all three conditions. Obesity is a gl ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  2. A cost-effective bioreactor to advance functional tissue engineering of cartilage

    SBC: Apex Biomedical Company, LLC            Topic: NIAMS

    DESCRIPTION (provided by applicant): Osteoarthritis (OA) is the leading cause of chronic disability in the United States. A clinical goal in the treatment and prevention of OA is to develop replacement cartilage using tissue engineering (TE) technologies. Although TE cartilage presently lacks the mechanical stability of native cartilage, studies have demonstrated that mechanical stability can be e ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  3. Additive Manufacturing Sensor Fusion Technologies for Process Monitoring and Control.

    SBC: X-Wave Innovations, Inc.            Topic: DLA18A001

    Additive Manufacturing (AM) is a modern and increasingly popular manufacturing process for metallic components, but suffers from well known problems of inconsistent quality of the finished product. Process monitoring and feedback control are therefore crucial research areas with a goal of solving this problem. To address this concern, X-wave Innovations, Inc. (XII) and the University of Dayton Res ...

    STTR Phase I 2018 Department of DefenseDefense Logistics Agency
  4. A Home Exercise Program (DVD) for Women with Infants and Young Children

    SBC: KLEIN BUENDEL, INC.            Topic: NIDA

    DESCRIPTION (provided by applicant): Becoming a mother is a significant transition in a woman's life. This transition can precipitate major changes in health behaviors, like physical activity. Once a woman has a child she is much less likely to participate in regular, moderate to vigorous physical activity compared to women without children. Thus, new mothers are at risk for future weight gain and ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  5. Alafair Biosciences develops cross-linked polysaccharide hydrogel films to addres

    SBC: ALAFAIR BIOSCIENCES, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): The goal of this STTR project is to develop a pre-formed, naturally-based hydrogel postoperative adhesion barrier with improved handling characteristics, laparoscopic deliverability, and consistent efficacy. Our technology is based on a novel, patented process that imparts exceptional elasticity and toughness on normally brittle, weak materials. Postoperative a ...

    STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  6. An Engineered Nanoimmunotherapy for Melanoma

    SBC: IMMUNOBLUE, LLC            Topic: NCI

    PROJECT SUMMARY Melanoma is one of the most prevalent cancers and is estimated to account for overdeaths inin the United States aloneAlthough highly curable when detected earlytheyear survival rates decline precipitously for patients with regionaland metastaticmelanoma indicating a lack of efficacy of conventional therapiesand a strong need for novel therapies for this patient populationIn respons ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  7. An innovative WGS platform for discovery, annotation, and interpretation of all forms of human genetic variation.

    SBC: Base2 Genomics LLC            Topic: 172

    PROJECT SUMMARY Modern DNA sequencing technologies have transformed our ability to interrogate human genomes in a single experimentthereby eliminating the inherent blind spots of gene panels and whole exome sequencingFurthermorerecent speed and economy improvements are driving the cost of whole genome sequencingWGSdown to that of WESthereforewe foresee a transition over the next two years to WGS a ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. An Interactive Informed Consent Program for Cardiac Procedures

    SBC: ARCHIE MD INC.            Topic: NHLBI

    DESCRIPTION (provided by applicant): Informed consent has become an essential component of the doctor-patient interaction. The informed consent process requires that patients not only be given information about proposed medical treatment, but that it be presented in an understandable way so the patient can make meaningful choices about medical alternatives. At the heart of the informed consent doc ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  9. Anti-inflammatory and Mitotic Properties of Non-hormonal Steroids in Lung Epithel

    SBC: REVERAGEN BIOPHARMA, INC.            Topic: NHLBI

    DESCRIPTION (provided by applicant): Asthma is a very common lung condition in children, and incidence is increasing in the US particularly in urban and minority populations. The standard of care for asthmatics is inhaled steroid, although clinical response is variable. The mechanism of efficacy of steroids in asthma is thought to be via anti-inflammatory pathways, although other anti-inflammatory ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  10. Antimicrobial Dental Devices and Waterlines

    SBC: SELENIUM LTD            Topic: NIDCR

    DESCRIPTION (provided by applicant): Bacterial contamination of dental water lines is a major concern in modern dentistry and may cause infection in dental patients with compromised immune systems. This includes patients with cancer, diabetes, or AIDS; cardiac patients who often require prophylactic antibiotics prior to dental treatment; the elderly, young children, and pregnant women. Bacterial l ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
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