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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Oxygen Production on Demand for Military Medical Needs

    SBC: GLOBAL RESEARCH & DEVELOPMENT INC            Topic: DHA17B005

    Topic 17B-005 calls for a new process for supplying medical grade O2 without the use of O2 bottles or pressure (or vacuum) swing absorption (PSA) technology. This is significant to the military for several reasons, because these two sources currently interfere with logistical supply of O2 to where it is required, namely field hospital units. PSA units reportedly have limited shelf life and supply ...

    STTR Phase II 2021 Department of DefenseDefense Health Agency
  2. Developing a Just-in-Time Refresher Trainer for Advanced Life Support in Austere Regions

    SBC: UNVEIL LLC            Topic: DHA20B001

    Early recognition of impending decompensation and appropriate intervention is critical to patient survival in many situations; yet, military personnel receive limited training about the early signs of decompensation through established training courses. Descriptions of respiratory distress, shock, and poor perfusion may be offered in training, but with little opportunity to practice recognizing th ...

    STTR Phase I 2021 Department of DefenseDefense Health Agency
  3. A rapid high-throughput device to isolate antibiofilm bacteriophage

    SBC: GUILD ASSOCIATES INC            Topic: DHA20B003

    Multi-drug resistant (MDR) bacterial infections are a global public health crisis with ESKAPEE (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, Enterobacter spp, and Escherichia coli.) pathogens particularly troublesome. Wound infection is usually acquired in the hospital setting and is a significant source of morbidity and morta ...

    STTR Phase I 2021 Department of DefenseDefense Health Agency
  4. Imaging biomarkers of severe respiratory infections in premature infants Phase II

    SBC: KITWARE INC            Topic: NHLBI

    ABSTRACTPrematurity is the largest single cause of death in children under five in the world and lower respiratory tract infections (LRTI) are the top cause of hospitalization and mortality in premature infants. Clinical tools to predict the risk and assess the severity of LRTI in premature babies are critically needed to allow early interventions to decrease the high morbidity and mortality in th ...

    STTR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
  5. Computer-aided design for improved lantibiotics

    SBC: Oragenics, Inc.            Topic: 400

    ABSRACT With the ever-increasing problem of antibiotic resistance and the concurrent use of antibiotics in the food chain and in agriculture, there is an urgent and unmet need for new classes of antibiotics. Lantibiotics represent a large untapped pipeline of attractive scaffolds for the development of novel antibiotics. Previous in vitro and in vivo studies support the concept that lantibiotics a ...

    STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  6. Developing a RPN13 inhibitor for the treatment of Quadruple Negative Breast Cancer

    SBC: Up Therapeutics LLC            Topic: 102

    Quadruple negative breast cancer (QNBC), lacking the expression of ER (estrogen receptor), PR (progesterone receptor), HER2 (human epidermal growth factor receptor 2) and AR (androgen receptor), is the breast cancer subtype with the worst prognosis, and QNBC disproportionately afflicts African Americans. It has no standard-of-care treatment targets and thus efficacious and safe treatments must be ...

    STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  7. A Peptide-Based Polyplex Platform for Nucleotides Delivery to the Sites of Inflammation

    SBC: Trasir Therapeutics, Inc.            Topic: 100

    AbstractRNA interference (RNAi) is an evolutionary conserved mechanism for post transcriptional control of protein expression in which short double-stranded RNA target specific messenger RNA (mRNA) for degradation, thus inhibiting protein translation. siRNA has great potential to revolutionize medicine by enabling highly specific and efficient silencing of proteins involved in disease pathogenesis ...

    STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  8. A MEMS-Based High-Throughput Photostimulation Device with Commercial Backplane Integration

    SBC: BOULDER NONLINEAR SYSTEMS, INC.            Topic: NIMH

    Boulder Nonlinear Systems (BNS) and Prof. Rikky Muller at UC-Berkeley propose a two-phase effort to address current speed limitations in holographic photostimulation. Specifically, the proposed innovations aim to achieve streaming of high-resolution holograms at up to 10,000 frames per second (fps) to enable closed-loop optogenetic control.Optical imaging and photostimulation have emerged as compl ...

    STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  9. Development of a biomarker panel for screening and early detection of gynecological cancers

    SBC: MDDx, Inc.            Topic: 102

    PROJECT SUMMARY It is estimated that more than 80,000 women will be diagnosed with ovarian (OvCA) and endometrial (EndoCA) cancers this year in the U.S. and this will result in the death of 26,000 women. There are no screening tests for either of these two female-specific cancers which also disproportionally affect ethnically distinct populations. For both cancers, detection of early stage, locali ...

    STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  10. Digital Accessible Remote Olfactory Mediated Health Assessments for Preclinical AD

    SBC: Aromha Inc            Topic: NIA

    Project Summary / Abstract Over 5.8 million Americans are currently affected by Alzheimerandapos;s disease (AD) with an economic burden estimated at andgt; $270 billion/year in 2020 that is projected to increase at least four fold over the next several decades. Accurate biomarkers have been developed that demonstrate that AD pathology is present 15 years of more prior to the onset of memory sympto ...

    STTR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
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