Award Data

Neck pain is a common and disabling health impairment affecting both military and civilian populations. Due to a lack of objective, reliable, and actionable metrics, occupational interventions and treatment plans are typically based on a trial-and error process that results in suboptimal outcomes and inflated costs. To address this problem, our objective will be to (1) develop an evidence-based te ...

Thegoal is to develop asoftwaretool that implementsa novelapproach applicableto fitgeneral pharmacologic, toxicology, or other biomedical data, that mayexhibita non-monotonic dose-responserelationship for which thecurrent parametricmodels fail. Thesoftwareexplores dose-responserelationships using both monotonicand non-monotonicmodels,and estimates theassociated doseresponsecurves,which can further ...

Until now,much of theresearch usingfunctional near-infrared spectroscopy (fNIRS) has focused on tailoringasystem to detect onlyafew cognitivestatesand theapplication of theseapproaches outsidethe laboratory is not well tested. This solution provides severely limited coverage of thespacethat this technology could beapplied to,and is notarealistic path for developing neuroimagingasan operational ass ...

Traumatic injuries account for 30% of all life years lost in the US and is the leading cause of death for people under 46 years of age. Uncontrolled bleeding or hemorrhage constitute 30-40% of trauma related deaths and are considered to be a major cause o

Defense Health Agency (DHA) is seeking a multi-functional diagnostic to determine blood coagulopathy in real time at point-of-care (POC). Blood coagulopathy, resulting in uncontrolled bleeding, is implicated in 80% of operating room deaths and 50% of trau

Most standard-of-care tools and techniques for evaluating neck disorders are subjective, unreliable, and do not provide actionable information for providers, payers, and organizations to deliver efficient and effective care. This lack of objective neck he

Ultrasound is a therapeutic modality which has been used clinically for 60 years, but has been limited in practice by the complexity of the technology. Recent research has allowed for the development of a portable, wearable, long duration, low intensity therapeutic ultrasound system. The system is powered by battery, and can be applied by a user to deliver up

Surgical simulations aiming to support surgeon practices and medical education have attracted enormous research effort over the last two decades. However, the physical reality, especially on simulating aggregated tissue interaction, is still unsatisfactory. In this proposed work, an open source surgery simulation framework, SoFMIS, will be utilized and enhanced with tissue interaction models to a ...

Traumatic injury represents one of the most common reasons for mortality and accounts for 14.2% of all fatalities. Clinical management of trauma and emergency surgeries in combat casualties often require massive plasma transfusions. However, in critical c

The ready availability of universal donor plasma to rapidly treat massively bleeding hospital trauma patients and warfighters with combat casualties is a key element of current recommendations for trauma resuscitation, yet universal AB donor plasma is rel