Award Data

Burns are a common and severe combat injury that require highly trained clinicians to diagnose and treat, especially for those severe burns that need an immediate excision. However, lack of burn experts in the far-forward military hospital and the challenge of accurate burn assessment presents a high risk for unnecessary transport of casualties. Thus, there is a critical need for a device to aid r ...

High concentrations of supplemental oxygen are used routinely by pilots and divers prior to and during missions to prevent and treat decompression sickness, avoid detection during covert operations, and to support oxygenation following pulmonary injury. Due to pulmonary oxygen toxicity (PO2T), exposure limits are imposed to prevent damage to pulmonary tissues. Current policy focuses on preventing ...

Different regions of the human GI tract exhibit different chemical environments and different digestion metabolites. As a result, these regions support different microorganisms, with gradients in metabolic products along the length of the GI tract. Single-point measurements of microbiome metabolites (e.g. in feces) are insufficient to provide detailed information of physiological status because th ...

This expansion effort will enable SoarTech to harden the C-CHAT prototype for use during field exercises and increase the current 4 TRL to a 7 TRL. Working with partners at the USMC Field Medical Training Battalion (FMTB) and the University of Central Florida (UCF), we will enhance C-CHAT to run as a stand-alone application on a DoD-approved Android smartphone (e.g., the Samsung Galaxy S20 Tactica ...

In emergency medicine, time is a critical factor that can significantly influence the survival of seriously ill patients. Early recognition of clinical deterioration and rapid initial management is paramount in any setting where emergency care is provided. In military medicine and humanitarian care, delivering high quality and timely care to injured patients poses even greater and more complex cha ...

The twenty-first century has seen a global rise in bacterial infections exhibiting antimicrobial-resistance (AMR). More than ninety percent of chronic wounds contain microbial biofilms that exhibit AMR, and the bacteria responsible for several of these recalcitrant infections are called ESKAPEE pathogens. Eradicating ESKAPEE pathogenic infections is challenging, but bacteriophage (phage) therapy i ...

According to the Department of Defense, there were more than 400,000 known TBI diagnoses in service members between 2000 and 2019 (DVBIC, 2020). Detection and measurement of potential injury due to blast overpressure and blunt impact have been priorities of the US military for many years, especially since Operation Enduring Freedom (OEF). Among those deployed, estimated rates of probable TBI range ...

Thegoal is to develop asoftwaretool that implementsa novelapproach applicableto fitgeneral pharmacologic, toxicology, or other biomedical data, that mayexhibita non-monotonic dose-responserelationship for which thecurrent parametricmodels fail. Thesoftwareexplores dose-responserelationships using both monotonicand non-monotonicmodels,and estimates theassociated doseresponsecurves,which can further ...

Until now,much of theresearch usingfunctional near-infrared spectroscopy (fNIRS) has focused on tailoringasystem to detect onlyafew cognitivestatesand theapplication of theseapproaches outsidethe laboratory is not well tested. This solution provides severely limited coverage of thespacethat this technology could beapplied to,and is notarealistic path for developing neuroimagingasan operational ass ...

Traumatic injuries account for 30% of all life years lost in the US and is the leading cause of death for people under 46 years of age. Uncontrolled bleeding or hemorrhage constitute 30-40% of trauma related deaths and are considered to be a major cause o