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The Award database is continually updated throughout the year. As a result, data for FY22 is not expected to be complete until September, 2023.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. A High-Throughput Blood Esterase Panel Assay

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD10108

    Organophosphorus chemical warfare nerve agents (OP-CWA) are attractive to terrorist groups and rogue states as an inexpensive and accessible technology for chemical warfare. OP-CWA and organophosphate pesticides cause severe neurological symptoms and death by inhibiting the enzyme acetylcholinesterase (AChE); the resulting excess acetylcholine accumulates and overstimulates the human or animal bo ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  2. Rapid, Non-Thermally Cured Composite Fabrication

    SBC: Luna Innovations Incorporated            Topic: DLA09001

    Composite materials, with their high strength to weight ratios, manipulative properties, and corrosion resistance are now widely utilized throughout the military. High performance composites are required for air, sea, and land platforms. One of the drawbacks of these composite systems is the excessive costs and time required for part manufacturing. Prolonged elevated temperature curing is typic ...

    SBIR Phase I 2010 Department of DefenseDefense Logistics Agency
  3. Low/No Power Detector for Organophosphate Nerve Agents

    SBC: Luna Innovations Incorporated            Topic: CBD10101

    Organophosphate (OP) nerve agents are the most dangerous chemical warfare agents and therefore pose a significant threat. Rapid and exact identification of the OP agent involved in any hazardous material incident could significantly facilitate the administration of the most effective therapeutic and allow for appropriate measures of protection and decontamination, thereby increasing survival of t ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  4. Residual Life Indicator for Adsorptive and Reactive Single-Pass Filtration Systems

    SBC: MORPHIX TECHNOLOGIES, INC.            Topic: CBD10106

    In peacetime environments, concerns over improbable encounter with agent threats are supplanted by the need to understand and assess the performance status or residual life (RL) capacity of sorbent-based technologies used in Collective Protection (ColPro) systems. Systems such as the M98 and M48A1 run continuously and therefore sample large volumes of outside air over their lifetime. It is well- ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  5. DEVELOPMENT OF A BIOSENSOR NANOFLUIDIC PLATFORM FOR INTEGRATION WITH TERAHERTZ SPECTROSCOPIC SYSTEM

    SBC: VIBRATESS            Topic: CBD10110

    The goal of this SBIR project is to develop and demonstrate an electrokinetically driven nanofluidic sensor device of the physical size and shape that will allow integration with a THz spectroscopic instrument. The substrate and channel surfaces within the device will be appropriate for the acquisition of THz-frequency spectroscopic features from bio-molecules (e.g., DNA, RNA, proteins) in soluti ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  6. Affinity Matrix System for Large-Scale Protein Purification

    SBC: Luna Innovations Incorporated            Topic: CBD12102

    Though vast improvements have been made in various protein expression platforms, limitations arise in the implementation of current purification methods. Traditional chromatographic methods are time intensive, carry heavy material costs, and are difficult to scale - reducing the benefits achieved in protein expression. Affinity-binding methods are promising for scale-up and swiftness of purificati ...

    SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
  7. Microhydrogel Depot for Sustained Delivery of Prophylactic Bioscavenger

    SBC: Luna Innovations Incorporated            Topic: CBD13107

    Neurotoxic organophosphorus (OP) agents (e.g. sarin, soman, VX and tabun) were developed initially as pesticides and adapted for chemical warfare. OP agents are fast acting and lethal at even very low doses. Countering the threat of intoxication by OP nerve agents is an important mission for homeland security. Currently, the most promising strategy to counter OP intoxication is to scavenge the age ...

    SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
  8. Anatomic 3D Synthetic Tissue Printer for Medical Training

    SBC: SERAPH ROBOTICS, INC.            Topic: DHP12003

    Military medical personnel are not prepared to provide trauma care to severely injured soldiers in wartime due to inadequate and unrealistic battlefield training opportunities during peacetime. Training has historically been done on human cadavers and live animals, but cadavers are in limited supply, and animal rights groups and physicians are increasing pressure to end the practice of using live ...

    SBIR Phase I 2013 Department of DefenseDefense Health Agency
  9. Prototype, Open-Source, Universal Healthcare Exchange Language

    SBC: SYSNET International, Inc.            Topic: DHP12004

    Use of information technology within the U.S. healthcare system has made considerable strides forward in the past few years but to fully realize the full benefits of an Electronic Health Record - including higher quality and safety of care through access to the patient"s complete health record at the point of care, increased participation by patients in their healthcare through access to a shared ...

    SBIR Phase I 2013 Department of DefenseDefense Health Agency
  10. Prototype Application of Mobile, Cloud-based, Watson-Like Technologies for TBI/PTSD Clinical Decision Support and Predictive Analytics

    SBC: Lifecom Inc.            Topic: DHP12005

    The goal of this Phase I project is to develop an engineering plan and to create a prototype for a mobile, cloud-based expert system to aid in diagnosis, decision support and predictive analytics to improve clinical outcomes for veterans, soldiers, and their families with traumatic brain injury (TBI) and posttraumatic stress disorder (PTSD). Lifecom, Inc. is a health information technology compan ...

    SBIR Phase I 2013 Department of DefenseDefense Health Agency
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