Award Data

Organophosphorus chemical warfare nerve agents (OP-CWA) are attractive to terrorist groups and rogue states as an inexpensive and accessible technology for chemical warfare. OP-CWA and organophosphate pesticides cause severe neurological symptoms and death by inhibiting the enzyme acetylcholinesterase (AChE); the resulting excess acetylcholine accumulates and overstimulates the human or animal bo ...

A need exists for advances in non toxic treatments for cover and barrier fabrics. Since polybrominated materials have been banned in many European countries and the production of a number of brominated additives terminated in the U.S. as well, future technologies must focus on non-halogenated treatments. In general, non-halogenated treatments (phosphates and borates) are not durable to aqueous sol ...

Composite materials, with their high strength to weight ratios, manipulative properties, and corrosion resistance are now widely utilized throughout the military. High performance composites are required for air, sea, and land platforms. One of the drawbacks of these composite systems is the excessive costs and time required for part manufacturing. Prolonged elevated temperature curing is typic ...

Organophosphate (OP) nerve agents are the most dangerous chemical warfare agents and therefore pose a significant threat. Rapid and exact identification of the OP agent involved in any hazardous material incident could significantly facilitate the administration of the most effective therapeutic and allow for appropriate measures of protection and decontamination, thereby increasing survival of t ...

In peacetime environments, concerns over improbable encounter with agent threats are supplanted by the need to understand and assess the performance status or residual life (RL) capacity of sorbent-based technologies used in Collective Protection (ColPro) systems. Systems such as the M98 and M48A1 run continuously and therefore sample large volumes of outside air over their lifetime. It is well- ...

The goal of this SBIR project is to develop and demonstrate an electrokinetically driven nanofluidic sensor device of the physical size and shape that will allow integration with a THz spectroscopic instrument. The substrate and channel surfaces within the device will be appropriate for the acquisition of THz-frequency spectroscopic features from bio-molecules (e.g., DNA, RNA, proteins) in soluti ...

Historical methods of reliability assessment are less and less effective as device sizes shrink. Already researchers are unable to package the many advanced devices because the act of cutting the wafer and the packaging operation pre-stresses or destroys the devices resulting in unreliable test results. Additionally the increasing cost of fabricating a wafer with advanced integrated circuit techno ...

Perform a feasibility study on developing a face recognition application in a cloud computing environment utilizing MBARK as the middleware. The application will have a client piece that will run on a mobile device and a server piece that will run on a higher-performance computing cluster. The specific objectives of the feasibility can be enumerated as follows: 1. Split/distribute the MBARK middle ...

Though vast improvements have been made in various protein expression platforms, limitations arise in the implementation of current purification methods. Traditional chromatographic methods are time intensive, carry heavy material costs, and are difficult to scale - reducing the benefits achieved in protein expression. Affinity-binding methods are promising for scale-up and swiftness of purificati ...

A prefilled auto-injector device for storing a beneficial agent in a dry and stable format alongside a diluent, and automatically delivering the beneficial agent to a patient after reconstitution. The device comprises an automatic needle insertion mechanism and automatic needle retraction mechanism and is safe and disabled after use. The primary drug container of the auto-injector is made from ...