Award Data

The objective of this proposal is to demonstrate the feasibility of producing an automated delayering and imaging system with end point detection, material density detection with built in neural network error correction. This process, coined fast Automated Delayering-Image Capture System (ADICS) leverages off of the existing Pix2Net which is a proven automated imaging 3D microchip reconstruction ...

Marburg virus (MARV) is a filamentous enveloped non-segmented negative sense RNA virus. This viruse is considered to be extremelydangerous with case fatality rates as high as 88-90%. Extensive efforts have gone towards effective vaccines for MARV prevention, however,none have been successfully established as licensed vaccines. Glycoprotein (GP) is the only surface protein of MARV. There are substa ...

Additive manufacturing (AM) has rapidly evolved into a valuable technique for making parts which, at times, cannot be fabricated through conventional machining methods.One challenge in the area of AM is the lack of real-time feedback on the fabrication process and the quality of the part being made.This is especially critical given the relatively long periods of time that complex parts can require ...

Traumatic brain injury is a common problem in both the military and civilian communities, but current treatment protocols are focused on managing symptoms and fail to prevent significant long-term repercussions. In the proposed program, Luna will demonstrate the feasibility of a liposome-based therapeutic delivery system capable of delivering hydrophilic and hydrophobic therapeutics to the traumat ...

Clinicians have recognized that the nature of diseases can be highly individual resulting in different patterns of onset and progression. In turn, the response of an individual to drugs is also unique and governed by a variety of factors. Pharmacokinetic models represent the movement of a drug through the body, and personalized pharmacokinetic models aim to capture the unique responses of specific ...

Estimation of the primary parameters like IC 50 in traditional dose-response modelsmay fail or lead to misleading results when the observations are non-onotonic due to drugresistance or virus mutation in various biomedical lab research. The objective of this project isto develop a novel approach to assess dose response relationship, which is applicable to generalpharmacologic, toxicologic, or othe ...

Investments by the Department of Defense (DOD) have led to the development and demonstration of electronic textiles capable of transforming traditional textile systems into wearable power and data systems. The Defense Health Agency (DHA) has identified an opportunity to leverage advancements in smart garment systems for military personnel to aid in the prediction in performance declines and healt ...

For this Phase I SBIR proposal, Vcom3D proposes to design advanced medical moulage that accurately simulates the progression of an injury or pathology by morphing through a series of clinical states to enable learners to confirm the progression of the wound and to determine whether iatrogenic errors or pathologies occurred duing treatment. The physical morphing moulage may be applied to medical m ...

Medical moulage is used in medical training to simulate injuries or pathologies, however current moulage is static and does not provide the trainee feedback on the quality of care or ultimate outcome of that care. Allowing a trainee to witness the injury or pathology -morph- while treatment is being provided can provide feedback on any potential mistreatment and enhance the learning and proficienc ...

Design Interactive Inc. (DI) and Eastern Virginia Medical School (EVMS) propose to develop an Augmented reality Learning Environment for Refresher Training (ALERT) that provides realistic and relevant Tactical Combat Casualty Care (TC3) scenarios using AR technologies integrated with mannequins for pre-deployment training and humans for deployed training environments. ALERT will facilitate learnin ...