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The Award database is continually updated throughout the year. As a result, data for FY22 is not expected to be complete until September, 2023.
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Virus-Like Particle Based pan-Marburgvirus VaccineSBC: Luna Innovations Incorporated Topic: CBD18A002
Marburg virus (MARV) is a filamentous enveloped non-segmented negative sense RNA virus. This viruse is considered to be extremelydangerous with case fatality rates as high as 88-90%. Extensive efforts have gone towards effective vaccines for MARV prevention, however,none have been successfully established as licensed vaccines. Glycoprotein (GP) is the only surface protein of MARV. There are substa ...STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
Smart Baseplate for Additive ManufacturingSBC: Luna Innovations Incorporated Topic: DLA18A001
Additive manufacturing (AM) has rapidly evolved into a valuable technique for making parts which, at times, cannot be fabricated through conventional machining methods.One challenge in the area of AM is the lack of real-time feedback on the fabrication process and the quality of the part being made.This is especially critical given the relatively long periods of time that complex parts can require ...STTR Phase I 2018 Department of DefenseDefense Logistics Agency
Additive Manufacturing Sensor Fusion Technologies for Process Monitoring and Control.SBC: SENVOL LLC Topic: DLA18A001
The Department of Defense (DoD) has a demand for out-of-production parts to maintain mission readiness of various weapons platforms. Additive manufacturing (AM) is an exciting and promising manufacturing technique that can make out-of-production parts and holds the potential to solve supply chain issues, such as high costs (i.e. for low-volume parts) and sole sourcing risks. The ability of AM to s ...STTR Phase I 2018 Department of DefenseDefense Logistics Agency
Functionalized, Therapeutic-Loaded Liposomes for the Acute Treatment of TBISBC: Luna Innovations Incorporated Topic: DHA18A001
Traumatic brain injury is a common problem in both the military and civilian communities, but current treatment protocols are focused on managing symptoms and fail to prevent significant long-term repercussions. In the proposed program, Luna will demonstrate the feasibility of a liposome-based therapeutic delivery system capable of delivering hydrophilic and hydrophobic therapeutics to the traumat ...STTR Phase I 2018 Department of DefenseDefense Health Agency
Probabilistic Pharmacokinetic Models for Diagnosis, Prognosis, and Personalized TreatmentSBC: BARRON ASSOCIATES INC Topic: DHA17B003
Clinicians have recognized that the nature of diseases can be highly individual resulting in different patterns of onset and progression. In turn, the response of an individual to drugs is also unique and governed by a variety of factors. Pharmacokinetic models represent the movement of a drug through the body, and personalized pharmacokinetic models aim to capture the unique responses of specific ...STTR Phase I 2018 Department of DefenseDefense Health Agency
Rapid SERS-based Detection of Sepsis and TBI BiomarkersSBC: Ionica Sciences, Inc Topic: DHA17B004
Traumatic brain injury (TBI) often occurs when a sudden trauma or head injury disrupts the function of the brain. Common causes of TBI include damage caused by explosive devices, falls and vehicle or motorcycle accidents. Sepsis is the result of a massive immune response to bacterial infection that gets into the blood. Sepsis often leads to organ failure or injury, and has always been a significan ...STTR Phase I 2018 Department of DefenseDefense Health Agency
Griffon Test SuiteSBC: SOAR TECHNOLOGY INC Topic: DHA17C001
In this proposal we support the development of a hypoxia test battery by designing and developing a domain general tool suite for processing, synchronizing, and evaluating data from cognitive, behavioral, and physiological measures.The proposed Griffon Tool Suite addresses many of the practical requirements demanded by a flexible test battery. The effort falls into three major thrusts.First, we pr ...STTR Phase I 2018 Department of DefenseDefense Health Agency
Combat Casualty Handoff Automated Trainer (CCHAT)SBC: SOAR TECHNOLOGY INC Topic: DHA17B001
Combat casualty handoffs are critical communication moments during which responsibility for the patient and important casualty information is transferred between providers. The nature of these handoffs requires specialized training, for which no standardized framework currently exists. The proposed effort aims to develop a capability, compatible with current DoD systems, that provides caregivers w ...STTR Phase I 2018 Department of DefenseDefense Health Agency
CCHAT Handoff ProtocolSBC: SOAR TECHNOLOGY INC Topic: DHA17B002
Research has identified that handoffs are particularly important communication processes, during which communication error can lead to patient safety situations. Organizations have created standard practices and training materials to encourage teamwork communication for handoffs, however these do not necessarily capture the needs of military medicine of combat casualty care. Combat casualty handof ...STTR Phase I 2018 Department of DefenseDefense Health Agency