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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Rapid SERS-based Detection of Sepsis and TBI Biomarkers

    SBC: Ionica Sciences, Inc            Topic: DHA17B004

    Traumatic brain injury (TBI) often occurs when a sudden trauma or head injury disrupts the function of the brain. Common causes of TBI include damage caused by explosive devices, falls and vehicle or motorcycle accidents. Sepsis is the result of a massive immune response to bacterial infection that gets into the blood. Sepsis often leads to organ failure or injury, and has always been a significan ...

    STTR Phase I 2018 Department of DefenseDefense Health Agency
  2. Virus-Like Particle Based pan-Marburgvirus Vaccine

    SBC: LUNA INNOVATIONS INCORPORATED            Topic: CBD18A002

    Marburg virus (MARV) is a filamentous enveloped non-segmented negative sense RNA virus. This viruse is considered to be extremelydangerous with case fatality rates as high as 88-90%. Extensive efforts have gone towards effective vaccines for MARV prevention, however,none have been successfully established as licensed vaccines. Glycoprotein (GP) is the only surface protein of MARV. There are substa ...

    STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
  3. Functionalized, Therapeutic-Loaded Liposomes for the Acute Treatment of TBI

    SBC: LUNA INNOVATIONS INCORPORATED            Topic: DHA18A001

    Traumatic brain injury is a common problem in both the military and civilian communities, but current treatment protocols are focused on managing symptoms and fail to prevent significant long-term repercussions. In the proposed program, Luna will demonstrate the feasibility of a liposome-based therapeutic delivery system capable of delivering hydrophilic and hydrophobic therapeutics to the traumat ...

    STTR Phase I 2018 Department of DefenseDefense Health Agency
  4. Fast Parameter Identification for Personalized Pharmacokinetics

    SBC: AUTONOMOUS HEALTHCARE INC            Topic: DHP17B003

    Drug dosingcan bemademore precise by using pharmacokineticand pharmacodynamicmodeling. Pharmacokinetics is thestudy of the concentration of drugs in tissueasafunction of timeand doseschedule,whereas pharmacodynamics is thestudy of therelationship between drugconcentration and drugeffect. By relating doseto resultant drugconcentration (pharmacokinetics)and concentration to effect (pharmacodynamics) ...

    STTR Phase I 2018 Department of DefenseDefense Health Agency
  5. Probabilistic Pharmacokinetic Models for Diagnosis, Prognosis, and Personalized Treatment

    SBC: BARRON ASSOCIATES, INC.            Topic: DHA17B003

    Clinicians have recognized that the nature of diseases can be highly individual resulting in different patterns of onset and progression. In turn, the response of an individual to drugs is also unique and governed by a variety of factors. Pharmacokinetic models represent the movement of a drug through the body, and personalized pharmacokinetic models aim to capture the unique responses of specific ...

    STTR Phase I 2018 Department of DefenseDefense Health Agency
  6. Circulating Diagnostic Markers of Infectious Disease

    SBC: PATHOVACS INCORPORATED            Topic: CBD18A001

    The focus of this STTR phase I component is on proof-of-concept studies demonstrating applicability of technical approaches for identificationof circulatory diagnostic markers for infectious disease. Therefore, the primary objective of this project is to determine feasibility of one suchtechnical approach called Proteomics-based Expression Library Screening (PELS), for identification of pathogen-d ...

    STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
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