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The Award database is continually updated throughout the year. As a result, data for FY21 is not expected to be complete until September, 2022.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. 3D Printed Multifunctional Brain Windows for Simultaneous Optical Imaging and Electrophysiology

    SBC: Applied Universal Dynamics, Corp.            Topic: 107

    PROJECT SUMMARY This proposal responds to PAR-18-870 titled “BRAIN Initiative: Development Optimization, and Validation of Novel Tools and Technologies for Neuroscience Research (STTR).” This project is a Fast Track STTR with a phase I and phase II. The small business, Applied Universal Dynamics Corp. (AUD) is collaborating with the University of Minnesota (U of MN). The activity patterns of t ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. A PORTABLE MULTI-MODAL OPTICO-IMPEDANCE SYTEM FOR EARLY WARNING OF PROGRESSION IN STABLE COVID-19 PATIENTS

    SBC: MULTIVARIATE SYSTEMS INC.            Topic: NIBIB

    Project Summary / Abstract: COVID-19, the clinical presentation associated with SARS-CoV-2 infection, has already profoundly impacted healthcare systems globally. Of particular note, communities such as long-term care facilities, assisted living communities, and prisons, are being devastated because of their high density of vulnerable individuals. Nursing home residents, which represent only 0.5% ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Validation of a salivary miRNA diagnostic test for autism spectrum disorder

    SBC: Quadrant Biosciences Inc.            Topic: 103

    Autism spectrum disorder (ASD) is a continuum of neurodevelopmental characteristics that includes deficits in communication and social interaction, as well as restrictive, repetitive interests and behaviors. ASD is an increasing public health concern, with about 1 in 45 American children diagnosed with ASD in 2014, a 10-fold increase in prevalence over the past 40 years. The effect of ASD on both ...

    STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  4. An unobtrusive monitoring device used for tracking asthma symptoms and lungfunction variability

    SBC: Clairways LLC            Topic: NHLBI

    Executive Summary of Predicate (One Page) Summary of Specific Aims of Phase I Specific Aim 1: Train and evaluate an algorithm to detect pediatric asthma symptoms (cough and wheeze) on a low power, small form factor wearable device. Specifications: 90% sensitivity; false alarm rate: 1 cough episode/day or 1 wheeze episode/day. Evaluate algorithm against medical expert (physician) scoring using the ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Pharmacologic Suppression of Reperfusion Injury Following Endovascular Thrombectomy In Stroke.

    SBC: BIOMIMETIX JV LLC            Topic: 102

    Ischemic stroke is a leading cause of death and disability in the United States. This often is attributable to thrombus formation at an atherosclerotic plaque or thromboembolism. Patients who present within 4.5 hours of symptom onset are eligible for thrombolysis with tissue plasminogen activator (tPA). This serves andlt;5% of victims. Recently, major advance has been made with proven efficacy fro ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Science Take-Out Kits for Improving Environmental Health Literacy on Vaping

    SBC: Science Take-Out, LLC            Topic: R

    ABSTRACT This supplement project will expand on our current STTR Phase I project in which we partnered with University of Rochesterandapos;s Environmental Health Sciences Center to develop three Science Take-Out vaping education kits. Our vaping education kits involve students in using hands-on activities and real-life scenarios to investigate the harmful effects of chemicals used in e-cigarette f ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. A Smart Sensing Drill to Reduce Incidence of Dental Implant Complications

    SBC: RyTek Medical Inc            Topic: NIDCR

    Clinical Importance: Almost 10 million dental implants were placed worldwide in 2016, with 3 million of these procedures taking place in the United States. The worldwide market for these implants is expected to increase to $4.0-$5.0 billion in revenue by 2018 as more patients opt for this procedure to regain chewing function and improve cosmetic appearance. The procedure itself requires an osteoto ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  8. DRIVEN: Accelerating Medical Entrepreneurship in the Northeast

    SBC: CELDARA MEDICAL, LLC            Topic: 500

    Project Summary This project describes the formation, launch and operation of the DRIVEN Accelerator Hub, with the express goal of reducing morbidity and mortality by increasing the number of medical entrepreneurs and their level of competency. The Hub is focused on the Northeast and, in collaboration with similar Hubs, will contribute nationwide. It will, in a facile, complete, and accessible way ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  9. In Vivo Studies of a Novel HDAC Inhibitor for Treating Hemoglobin Disorders

    SBC: Cetya Therapeutics, Inc.            Topic: NHLBI

    PROJECT SUMMARY The β-hemoglobinopathies are prevalent genetic blood diseases with few treatment options. It is estimate that 7% of the worldandapos;s population carries an abnormal hemoglobin gene with 400,000 infants born annually with a severe life threatening hemoglobinopathy. Drug mediated induction of normal, but developmentally silenced, fetal hemoglobin (HbF) expression reduces anemia and ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Validation of Novel Therapeutic Approach for Leptomeningeal Metastases

    SBC: Minnetronix Medical, Inc.            Topic: 102

    ABSTRACT Leptomeningeal Metastases (LM) is a condition in which tumor cells from a primary tumor metastasize, invade the subarachnoid space (SAS) and spread throughout the cerebrospinal fluid (CSF), resulting in seeding along the meninges, brain and spinal cord. LM represents a devastating event of cancer progression. There are 30,000 cases annually and currently no cure, with average survival of ...

    STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
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