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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Micro-endoscopic impedance sensing for surgical margin assessment

    SBC: RYTEK MEDICAL INC            Topic: 102

    ABSTRACT The primary objective of surgical therapy for the treatment of patients with any cancer is to remove all cancer cells from within the bodywith the secondary objective of maintaining organ functionThe primary pathological metric used to rate the success of a surgical procedure is evaluation of the surgical margin of the resected tissue specimenpost operativelyThis typically involves cuttin ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Targeting bacteria, the innate response of the middle ear to infection, and host-pathogen interactions, using topical and transtympanic applications for the treatment of otitis media.

    SBC: EARNANO LLC            Topic: NICHD

    Otitis media is a world wide disease primarily affecting the pediatric population under the age ofyearsIt is the most common reason for pediatric care visits and antibiotic therapyOver prescription and poorcompliance have led to a reduced susceptibility of bacteria to antibiotics andconsequentiallyto recurrent and chronic ear diseasesClearlythere is a compelling need to investigate alternative the ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. An unobtrusive monitoring device used for tracking asthma symptoms and lungfunction variability

    SBC: CLAIRWAYS LLC            Topic: NHLBI

    Executive Summary of Predicate (One Page) Summary of Specific Aims of Phase I Specific Aim 1: Train and evaluate an algorithm to detect pediatric asthma symptoms (cough and wheeze) on a low power, small form factor wearable device. Specifications: 90% sensitivity; false alarm rate: 1 cough episode/day or 1 wheeze episode/day. Evaluate algorithm against medical expert (physician) scoring using the ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. 3D Printed Multifunctional Brain Windows for Simultaneous Optical Imaging and Electrophysiology

    SBC: Applied Universal Dynamics, Corp.            Topic: 107

    PROJECT SUMMARY This proposal responds to PAR-18-870 titled “BRAIN Initiative: Development Optimization, and Validation of Novel Tools and Technologies for Neuroscience Research (STTR).” This project is a Fast Track STTR with a phase I and phase II. The small business, Applied Universal Dynamics Corp. (AUD) is collaborating with the University of Minnesota (U of MN). The activity patterns of t ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. DR?1-MOG as a Next-Generation Immunotherapy for Methamphetamine Use Disorder

    SBC: VIROGENOMICS BIODEVELOPMENT INC            Topic: R41

    Methamphetamine use disorder is associated with damage to regions of the brain that control cognitive and psychiatric functionOne third to one half of adults with methamphetamine use disorder experience cognitive impairments and other psychiatric symptoms that significantly impact treatment outcomesincreased relapse and lower treatment retention ratesMounting evidence demonstrates how immune facto ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Reward-based technology to improve opioid use disorder treatment initiation after an ED visit

    SBC: Q2I, LLC            Topic: NIDA

    Project Summary Abstract Millions of people in the US misuse opioids each yearleading to thousands of deaths and costing billions of dollars in total economic burdenMedication assisted treatmentMATfor opioid use disorderOUDis highly efficaciousbut only a fraction of OUD persons access MATand treatment non adherence is common and associated with poor outcomesThis STTR Fast Track proposal is designe ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. An Open-Sourced Imaging Ultrasound Platform

    SBC: CREARE LLC            Topic: NIBIB

    PROJECT SUMMARY ABSTRACTUltrasound isand is poised to remaina ubiquitous biomedical imaging modalityIt is safefasteffectiveand affordableUltrasound imaging innovations are being actively developed to provide inexpensive solutions to public health concerns in areas as diverse as early cancer detectiontargeted drug deliveryand image guided surgeryYet significant barriers to research and innovation i ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Ultrasound-coupled electrical impedance tomography for assessment of neuromuscular disorders

    SBC: RYTEK MEDICAL INC            Topic: NIAMS

    PROJECT SUMMARY ABSTRACT Clinical NeedThe coming decades promise a revolution in the therapies available for patients with generalized neuromuscular diseasesGNMDsincluding muscular dystrophyamyotrophic lateral sclerosisspinal muscular atrophymyasthenia gravisand a variety of acquired myopathiesHoweverin order to help facilitate thisthe academic and industrial clinical research communities need imp ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Technology Improving Success of Medication-Assisted Treatment in Primary Care

    SBC: Q2I, LLC            Topic: NIDA

    Project Abstract The opioid epidemic is the U S andapos s most widespread behavioral public health problemwith a higher number of deaths due to drug overdose incompared to deaths due to HIV at the peak of the AIDS epidemicMedication assisted treatmentMATfor opioid use disorderOUDis highly efficaciousHoweveronly a fraction of persons with OUD access MATand treatment non adherence and drop out is co ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. A PORTABLE MULTI-MODAL OPTICO-IMPEDANCE SYTEM FOR EARLY WARNING OF PROGRESSION IN STABLE COVID-19 PATIENTS

    SBC: MULTIVARIATE SYSTEMS INC.            Topic: NIBIB

    Project Summary / Abstract: COVID-19, the clinical presentation associated with SARS-CoV-2 infection, has already profoundly impacted healthcare systems globally. Of particular note, communities such as long-term care facilities, assisted living communities, and prisons, are being devastated because of their high density of vulnerable individuals. Nursing home residents, which represent only 0.5% ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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