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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Development of Spleen Tyrosine Kinase (SYK) negative allosteric modifiers for therapeutic intervention in Alzheimer's disease.

    SBC: ARCHER PHARMACEUTICALS, INC.            Topic: NIA

    Pathological hallmarks of Alzheimerandapos s diseaseADinclude extracellular deposits of Apeptidesintraneuronal aggregates of abnormally phosphorylated tau protein and neuroinflammationMost proposed AD disease modifying therapies have focused on strategies that reduce brain Aamyloid or tau pathological accumulationHoweversuch approaches have been unsuccessful in late stage AD clinical trials and ma ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Technology for the non-invasive surveilance of post-traumatic compartment syndrome

    SBC: Myolex Inc            Topic: NIAMS

    PROJECT SUMMARYAcute compartment syndromeACSremains one of the most devastating and often overlooked traumatic musculoskeletal disorders in clinical practiceIn this conditionpressure increases in one of the body s spacelimited compartmentsdue most commonly to direct trauma or bone fractureresulting ultimately in an ischemic injury to all of the compartment s contentsincluding muscle and nerveOnce ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Development of a Clinical Screening Platform for Type 1 Diabetes

    SBC: Op-T-Mune, Inc            Topic: NIDDK

    AbstractA major shortfall in clinical care for diabetes is a rapid and accurate screen for progression to diseaseCurrent criteria involve HLA haplotypeand the presence of auto antibodiesAAGenome wide associated studiesGWASrevealed only immune associated genes including HLA as T D predictorsThe ability to differentiate from other diseases was very limitedPre typediabetesp T Dis now being identified ...

    STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  4. High Performance Simulation Tool for Multiphysics Propulsion Using Fidelity-Adaptive Combustion Modeling

    SBC: STREAMLINE NUMERICS, INC.            Topic: T1

    The innovation proposed here is a Pareto-Efficient Combustion (PEC) model for fidelity-adaptive combustion modeling capability implemented into the Loci-STREAM CFD code for use at NASA for simulation of rocket combustion. This work will result in a high-fidelity, high-performance multiphysics simulation capability to enhance NASA’s current simulation capability of unsteady turbulent reacting flo ...

    STTR Phase II 2018 National Aeronautics and Space Administration
  5. Launch Weather Decision Support System

    SBC: Radiometrics Corporation            Topic: T1

    NASA wants a cost-effective atmospheric remote sensing system providing accurate temperature and humidity profiles to least 10 km height in clear and cloudy conditions. Radiometrics Microwave Profiler (MP) products currently provide accurate temperature and humidity profiles in good agreement with radiosondes to 3 km height. Good agreement can be extended beyond 10 km height using variational retr ...

    STTR Phase II 2018 National Aeronautics and Space Administration
  6. uG-LilyPond- Floating Plant Pond for Microgravity

    SBC: Space Lab Technologies, LLC            Topic: T7

    Regenerative space life support will undoubtedly require food production, to recover nutrients and close the carbon loop in a spacecraft habitat. Aquatic plants have enormous potential for edible biomass production but have been little studied as potential food crops for space applications. The proposed μG-LilyPond™ is an autonomous environmentally controlled floating plant cultivation system ...

    STTR Phase II 2018 National Aeronautics and Space Administration
  7. CORC; Cable Based High Field Hybrid Magnets for Future Colliders

    SBC: Advanced Conductor Technologies LLC            Topic: 26b

    "The next generation of very high field accelerator magnets (20 T or more) are expected to be made with high-temperature superconductors (HTS) along with conventional low-temperature superconductors (LTS) to reduce cost. The operation and protection of these magnets becomes very challenging particularly if the HTS coils are made with the tapes and operate at a much lower current than the LTS coils ...

    STTR Phase II 2018 Department of Energy
  8. Scaleup of a Combined Spray Pyrolysis and Fluidized-bed Reactor Method for the Production of High Performing Layered Nickel- rich Cathode Materials as a Continuous Process

    SBC: HAZEN RESEARCH, INC.            Topic: 14a

    To increase the utilization of electric vehicles, the US Department of Energy is seeking to reduce the cost of electric vehicle batteries to less than $125/kWh by 2022. To achieve this goal, the costs of cathode materials, which account for approximately 30% of the cost of vehicle batteries, must be reduced significantly. To address the challenge of lowering the costs of advanced lithium battery c ...

    STTR Phase II 2018 Department of Energy
  9. A ratcheting prosthetic partial finger using advanced rapid manufacturing technology

    SBC: POINT DESIGNS, LLC            Topic: NICHD

    The Point PartialA Ratcheting Prosthetic Partial FingerUsing Advanced Rapid Manufacturing Technology Project SummaryAbstract The goal of the proposed project is to develop a purely mechanicalratcheting prosthetic partial fingerthe Point Partialwhichhas an industry leading strength to weight ratiocan be operated unilaterallyone handedoffers anatomical rotation and flexion around the patient s proxi ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Development lightmap rendering technology to advance infrared simulation capabilities for training applications

    SBC: Cornerstone Software Solutions, Inc            Topic: AF17AT012

    Recent technology advances have enabled the simulation community to achieve greater realism in virtual training environments, including physics-based simulated sensor views. As new methods for sensor view generation are developed, the lack of readily available supporting data to populate these specialized techniques limits their implementation. Currently the capability is not available to efficien ...

    STTR Phase II 2018 Department of DefenseAir Force
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