Award Data

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is to enable rapid blood clotting in order to treat bleeding after a traumatic injury The majority of deaths that occur within the first 24 hours following a traumatic injury are the result of hemorrhage. The scientific merits of the project stem from the biochemical advantages of using the ph ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) project will be the development of technology to decouple growth from product formation in microbes used for biomanufacturing. The goal is to address current limitations in the field of metabolic engineering for the production of high value products. Current approaches must balance the complex requirements of ...

The broader impact/commercial potential of this Small Business Innovation Research Phase I project is a novel tree bio-herbicide to prevent sprouting of stumps and girdled trees. If successful, it would replace synthetic chemical herbicides currently used to stop stump sprouting, cull unwanted trees, prevent disease, and control invasive species in national parks and forests, managed timberlands, ...

The broader impact/commercial potential of this Small Business Innovation Technology Transfer Research Phase I project is to facilitate the manufacturing and commercialization of natural and semi-synthetic products namely core lupane triterpenoids (betulin, betulinic acid, lupeol, betulinic aldehyde) as precursors for drug development and other industrial applications. Research shows that these tr ...

The broader impact/commercial potential of this project lies in next generation gas turbines where the heart of the engine, the combustor and the blade, are constructed from ceramic matrix composites (CMCs). These developments will spell a new phase of air transportation beyond the current engines that rely upon nickel-base superalloys, which have reached their maximum capability. The ceramic engi ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project promotes a promising new approach to improve employee wellness with the potential for wider application beyond the workplace. This improved approach combines both innovative clinical diagnostics with computer assisted learning to guide recommendations. It offers the potential to curb epidemic ...

This Small Business Technology Transfer Phase I project is for the development of a triboluminescent sensor system (ITOFPress) for quasi-distributed load sensing along the length of a wind blade for active control of wind turbines. According to experts, this innovation could result in a 20% increase in wind turbine power generation through enhanced inputs for active turbine control and better unde ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project will be to develop reliable technology for the production of aptamer pairs. Aptamers are core reagents in emerging markets, regarded as alternatives to monoclonal antibodies in therapeutics, diagnostics, and imaging. They possess several appealing qualities: Ease of in vitro synthesis, flexibl ...

This STTR Phase I project addresses the problem of embedded energy in the manufacture of magnesium metal for use in vehicle light-weighting. Improving fuel economy by incorporation of light metals, especially magnesium, does not save on total lifecycle energy consumed if the magnesium was produced using conventional methods. The most energy efficient production method known is a process technology ...

Surgical simulations aiming to support surgeon practices and medical education have attracted enormous research effort over the last two decades. However, the physical reality, especially on simulating aggregated tissue interaction, is still unsatisfactory. In this proposed work, an open source surgery simulation framework, SoFMIS, will be utilized and enhanced with tissue interaction models to a ...