Award Data

Based on encouraging Phase I feasibility results, we propose developing a novel gene therapy approach to promote guided vascular regeneration in treating extremities after traumatic injury. Our approach is to provide thread-like implants comprised of aligned nanofibrillar collagen scaffolds loaded with Hepatocyte Growth Factor (HGF) vectors (e.g., HGF DNA plasmid, modified mRNA) designed to enhanc ...

The ready availability of universal donor plasma to rapidly treat massively bleeding hospital trauma patients and warfighters with combat casualties is a key element of current recommendations for trauma resuscitation, yet universal AB donor plasma is rel

Based on our success in developing the world first commercial high energy femtosecond fiber laser system and our leading proprietary technology development in ultrashort pulsed fiber laser material processing, PolarOnyx proposes, for the first time, a compact high energy fiber laser based smart wound healing tool to meet with the requirement of this DHP solicitation. It includes a high energy fs f ...

Between Operation Iraqi Freedom, Operation Enduring Freedom, and Operation New Dawn, the total number of U.S. Casualties (those Wounded in Action) has exceeded 52,000 as of January 30, 2015. These numbers point to the fact that active warfighters in the battlefield are almost constantly exposed to the threat of external penetrating wounds. The goal of combat wound care is to protect open wounds u ...

Surgical simulations aiming to support surgeon practices and medical education have attracted enormous research effort over the last two decades. However, the physical reality, especially on simulating aggregated tissue interaction, is still unsatisfactory. In this proposed work, an open source surgery simulation framework, SoFMIS, will be utilized and enhanced with tissue interaction models to a ...

Results Group, LLC, in collaboration with the Southern Arizona Limb Salvage Alliance (SALSA) and other stakeholders will, in this 6-month program, establish proof of principle that non-motorized footwear can translate biomechanical leverage to confer similar load-reducing benefits as found in Total Contact Casts improving return to employment and healthy function. Aligned with patient-centered ca ...

This project develops a crowd-sourced English-to-ASL translation environment (CrEATE) to provide online English-to-ASL translation services and other assistive products for Deaf persons whose first language is American Sign Language (ASL) with the goal to improve the access of Deaf persons to English text in educational, job, health, and everyday settings. The projects builds on SigningAvatar tech ...

This project is developing a scalable Accessible Environmental Information Application (AEI) with seamless outdoor to indoor navigation and a unified beacon database for people with visual disabilities. This application provides indoor orientation information to assist in navigating indoor public spaces including malls, airports, conference venues, and baseball stadiums. This project is expanding ...

This project develops an advanced, portable hemodialysis regeneration system that significantly enhances the quality of life of end-stage renal disease (ESRD) patients. ESRD impairs physiological systems and functions, and is associated with disability, high morbidity and mortality. Hemodialysis is prescribed for the majority of individuals in the final stages of renal failure. Minimizing the loss ...

This project develops, deploys, and evaluates Embedded Access to Signing of Science Terms and Definitions (EAS): a client-server software system that delivers American Sign Language (ASL) and Signed English (SE) language support to Deaf and hard-of-hearing (Deaf/HH) students accessing any Web page that includes science, math, or healthcare information. The goal of this project is make scientific a ...