Award Data

Early detection of virulent infectious pathogens is critical to blocking the devastating epidemic spread of the pathogen and the potential harm this could have on our armed forces and general populations. In Phase I, we have utilized the state-of-the-art QuantiGene 2.0 technology to establish an assay for the sensitive quantification of SARS (epidemic spread in 2001) and assessing plasma DNA level ...

The development of compact, ultra-low drive voltage optical phase modulators is a critical key component for passive antenna remoting applications, a strategic area, part of a number of current and upcoming DARPA initiatives. With the development of sufficiently low V-pi modulators, passive front-ends can be constructed with a low figure even for a moderate optical pumping power. The combination o ...

In this Phase II proposal, the main thrust is to build a hardware MCICD prototype, and validate the FAR/FNR through real vehicle testing. By leveraging the existing LADAR based sensing platform in CMU, we expect to shorten the development cycle and reduce the overall cost. Extensive real vehicle testing is expected both in staged scenarios and in normal traffic. In this Phase II program, we also p ...

Cost effective semiconductor processing tools that enable the high-resolution nano-fabrication of low-volume electronics are needed by the DOD. The printing of ultra-fine gratings on silicon wafers using interference immersion lithography is envisaged as a first maskless process step in the fabrication of advanced application specific integrated circuits. Next generation interference immersion lit ...

The challenges faced by airborne and ground-based sensors in detecting, classifying, identifying, associating and tracking difficult moving targets, such as insurgent forces, operating in difficult terrain such as mountains and forests will be addressed. Our team will quantify the performance that can be achieved using multi-sensor, multi-spectral, and multi-platform techniques, where the sensors ...

The increasing use of video in force protection, autonomous vehicles reconnaissance, and surveillance in general has created a great demand for automated analysis and monitoring. It is infeasible to have humans monitoring and analyzing the vast amount of video used in such surveillance, and automated analysis yields hope to ease the burden and increase the amount of information extracted from col ...

DESCRIPTION (provided by applicant): Resident assistants (RAs) are often the first staff members at a college or university to learn that a student is engaged in alcohol or other drug abuse. This Phase II STTR application seeks support to further develop and test a web-based program called RA Resources (RAR) - Alcohol-Drug Problems. Phase 5, Inc. will conduct this theory-driven research project ...

DESCRIPTION (provided by applicant): The current proposal responds to program announcement PA-09-081, which has extended and replaced our Phase I announcement PAS-06-131 Applications of Imaging and Sensor Technologies for Clinical Aging Research. The purpose of the announcement is to improve imaging methods for measuring age-related changes in regulation of complex physiologic systems, including ...

DESCRIPTION (provided by applicant): In the past years, we have shown that human umbilical cord blood cells (HUCBC, U-CORD- CELL ) provide cognitive recovery in animal models of neurodegenerative disease. Infusion of HUCBC resulted in reduced infarct volume as well as in rescue of behavioral benefits in an animal model of stroke. We further showed that HUCBC infusion proved to be beneficial in ani ...

DESCRIPTION (provided by applicant): Degenerative joint disease accounts for substantial human suffering at tremendous social and economic cost. While prosthetic joint replacement is a well-established procedure, a finite life span makes this treatment unacceptable for younger or active individuals who often require progressively complicated revision surgeries. The goal of this Phase II STTR is to ...