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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. ESSP Drug Abuse Prevention Screening Tool: Phase II

    SBC: FLYING BRIDGE TECHNOLOGIES            Topic: N/A

    DESCRIPTION (provided by investigator): This application seeks Phase II funding to continue the development of the Elementary School Success Profile (ESSP) Drug Abuse Prevention Sreening Tool. The long-term objective is to help school-based health and mental health professionals quickly and accurately assess students' risk and protective factor status for adolescent substance use and other harmfu ...

    STTR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  2. Gene Therapy for Human Malignant Melanoma

    SBC: Introgen Therapeutics, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Melanoma is the most malignant of skin cancers. In the USA, the incidence of melanoma is increasing more rapidly than any other cancer. Melanoma is the most frequently occurring cancer in women from the ages of 25-30, and has recently replaced leukemia as responsible for the most lost work hours in the United States. Currently there is no approved therapy tha ...

    STTR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  3. Rational Development of Thyroid Receptor Antagonists

    SBC: MOLSOFT, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Molsoft proposes to develop antagonist lead molecules against the thyroid hormone receptor (TR) with IC50s in the low nanoM range and favorable bioavailability, specificity, and toxicity profiles. Proof of concept was achieved in Phase I Molsoft's virtual ligand screening technology allowed the discovery of 14 small molecule TR antagonists displaying extreme s ...

    STTR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  4. High Throughput Genotyping Technology

    SBC: PARALLELE BIOSCIENCE, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The Molecular Inversion Probe technology has been developed to allow 1000 SNPs to be called in a single tube. This technology holds the promise of enabling large scale inexpensive genetic analysis including the analysis of whole genomes. Before such studies can be contemplated, further platform development is required. Software tools must be developed to proces ...

    STTR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  5. Variation Scanning with Mismatch Repair Detection (MRD)

    SBC: PARALLELE BIOSCIENCE, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): One widely considered approach to identify susceptibility alleles is through linkage disequilibrium (LD) between these alleles and a universal set of relatively frequent SNPs distributed in all or most ethnic populations. This approach, however, may be unrealistic when variant alleles responsible for disease susceptibility are infrequent or are specific to a pa ...

    STTR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  6. A virus/cell based assay for discovery of anti-HIV drugs

    SBC: PTC THERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Highly active antiretroviral therapy (HAART) has had a great impact upon reducing AIDS related morbidity and mortality. However, due to the high degree of HIV-1 variation, novel strains resistant to the present HAART cocktail of drugs have arisen. Coupled with the considerable toxicity associated with HAART, there is significant need for the discovery of new ...

    STTR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  7. Control of Biofilms by Natural Products

    SBC: SEQUOIA SCIENCES, INC.            Topic: N/A

    N/A

    STTR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  8. Prophylactic Anthrax Toxin Vaccine

    SBC: VICAL, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Vical Inc. seeks SBIR Phase II funding to develop and produce a licensable prophylactic anthrax vaccine. This project will move on an accelerated but realistic timeline with plans for human clinical trials to begin in September 2003. Although many candidate vaccines are being studied for anthrax prevention or post-exposure prophylaxis, the Vical approach has ...

    STTR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  9. Recognition and Referral Skills for RAs- Alcohol-Drug Problems

    SBC: PHASE 5, INC.            Topic: NIAAA

    DESCRIPTION (provided by applicant): Resident assistants (RAs) are often the first staff members at a college or university to learn that a student is engaged in alcohol or other drug abuse. This Phase II STTR application seeks support to further develop and test a web-based program called RA Resources (RAR) - Alcohol-Drug Problems. Phase 5, Inc. will conduct this theory-driven research project ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  10. Comprehensive MR Imaging of Elderly Vascular Function: Phase II

    SBC: MRI CARDIAC SERVICES, INC.            Topic: NIA

    DESCRIPTION (provided by applicant): The current proposal responds to program announcement PA-09-081, which has extended and replaced our Phase I announcement PAS-06-131 Applications of Imaging and Sensor Technologies for Clinical Aging Research. The purpose of the announcement is to improve imaging methods for measuring age-related changes in regulation of complex physiologic systems, including ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
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