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The Award database is continually updated throughout the year. As a result, data for FY21 is not expected to be complete until September, 2022.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Combat Systems of the Future

    SBC: Advanced Systems/Supportability Engineering Technologies And Tools, Inc.            Topic: N05149

    The S-351 mini-sub is a prototype of the Dry Combat Submersible (DCS). This prototype was established as a means of risk reduction prior to a full commitment to the DCS program. Both of these platforms have an operational need to transit with minimum operator fatigue safely to a pre-defined point and covertly deploy and retrieve SEALS. To meet these operational needs, these platforms require upgra ...

    STTR Phase II 2017 Department of DefenseSpecial Operations Command
  2. Pre-clinical Development of a Broad Spectrum Antiviral Compound to Treat Human Pa

    SBC: NANOVIR, LLC.            Topic: NIAID

    DESCRIPTION (provided by applicant): The proposal seeks support for the pre-clinical development of broad spectrum compounds for treatment of human papillomavirus (HPV). HPV, the most common sexually-transmitted virus, is the cause of cervical dysplasia and cervical cancer. It has also been implicated in several other hyperproliferative diseases, such as cancers of the mouth and anus, as well as t ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  3. HUCBC modulation of Alzheimer's-like pathology and behavioral changes

    SBC: SANERON CCEL THERAPEUTICS, INC.            Topic: NIA

    DESCRIPTION (provided by applicant): In the past years, we have shown that human umbilical cord blood cells (HUCBC, U-CORD- CELL ) provide cognitive recovery in animal models of neurodegenerative disease. Infusion of HUCBC resulted in reduced infarct volume as well as in rescue of behavioral benefits in an animal model of stroke. We further showed that HUCBC infusion proved to be beneficial in ani ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  4. Liquid cooled viscoelastic actuation for robust legged robot locomotion

    SBC: APPTRONIK INC            Topic: H601

    Apptronik Systems in cooperation with the University of Texass Human Centered Robotics Lab (HCRL), Carnegie Mellon Universitys Robotics Institute and Italys National Research Institute (CNR), will collaborate to develop a new type of exoskeleton that is founded upon Apptroniks Visco-Elastic Liquid Cooled Actuator (VLCA). The fundamental goal of this program is the development of a powered exoskel ...

    STTR Phase II 2017 Department of DefenseSpecial Operations Command
  5. New generation of catheters for treatment of atrial fibrillation

    SBC: NOCTURNAL PRODUCT DEVELOPMENT, LLC            Topic: NHLBI

    DESCRIPTION provided by applicant Atrial fibrillation AF remains the most commonly occurring cardiac arrhythmia It is associated with a lower quality of life and a higher rate of morbidity andamp mortality primarily due to poor hemodynamics and often stroke One of the main options to treat atrial fibrillation is to ablate abnormal sources of electrical activity using percutaneous radiofrequ ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Aspirin-PC for Chemoprevention of Colorectal Cancer

    SBC: PLx Opco Inc.            Topic: NCI

    ABSTRACT Colorectal cancerCRCis the third leading cause of cancer related deaths in the U SBased on numerous epidemiological studies and recent prospective clinical trialsthe use of daily aspirin is associated with a significant reduction in CRC incidencedeaths and metastatic spreadHoweverthe chronic use of this drug is limited due to the side effects of gastrointestinal bleeding ulceration in sus ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  7. A Home Exercise Program (DVD) for Women with Infants and Young Children

    SBC: KLEIN BUENDEL, INC            Topic: NIDA

    DESCRIPTION (provided by applicant): Becoming a mother is a significant transition in a woman's life. This transition can precipitate major changes in health behaviors, like physical activity. Once a woman has a child she is much less likely to participate in regular, moderate to vigorous physical activity compared to women without children. Thus, new mothers are at risk for future weight gain and ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  8. Acute-infarct selective cardiac MRI contrast agent

    SBC: ELGAVISH PARAMAGNETICS, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant The overall goal of this project is to demonstrate the ability of our acute myocardial infarct selective paramagnetic contrast agent Gadolinium ABE DTTA to differentiate between acute and chronic infarcts in a reliable manner using contrast enhanced magnetic resonance imaging ceMRI In our Phase I data we have shown that Gd ABE DTTA exclusively highlight ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  9. Lactoferrin Modulation of Granuloma Pathology

    SBC: Pharmareview Corporation            Topic: NIAID

    ABSTRACT Host immunity plays a major role in development of Tuberculosis diseaseTuberculosis infected individuals respond by formation of granulomaswhich contain bacilliHoweverorganisms within granulomas are protected from the full scope of immune mediated defensesWe hypothesize that modulation of destructive immune mediated pathologywhile preserving essential immune responseswill allow more effec ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  10. MyFAP: A Multimedia Intervention for Adolescents and Young Adults with FAP

    SBC: Radiant Creative Group, LLC            Topic: NCI

    DESCRIPTION (provided by applicant): In this Phase II STTR application, we will build upon work conducted in our successful Phase I project which established the technical merit, acceptability and feasibility of developing a Web-based intervention, MyFAP.org, for adolescents and young adults (AYAs) with familial adenomatous polyposis (FAP). The main research goal of Phase II is to evaluate the eff ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
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