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The Award database is continually updated throughout the year. As a result, data for FY21 is not expected to be complete until September, 2022.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Probabilistic Pharmacokinetic Models for Diagnosis, Prognosis, and Personalized Treatment

    SBC: BARRON ASSOCIATES, INC.            Topic: DHA17B003

    Clinicians have recognized that the nature of diseases can be highly individual resulting in different patterns of onset and progression. In turn, the response of an individual to drugs is also unique and governed by a variety of factors. Pharmacokinetic models represent the movement of a drug through the body, and personalized pharmacokinetic models aim to capture the unique responses of specific ...

    STTR Phase I 2018 Department of DefenseDefense Health Agency
  2. Functionalized, Therapeutic-Loaded Liposomes for the Acute Treatment of TBI

    SBC: Luna Innovations Incorporated            Topic: DHA18A001

    Traumatic brain injury is a common problem in both the military and civilian communities, but current treatment protocols are focused on managing symptoms and fail to prevent significant long-term repercussions. In the proposed program, Luna will demonstrate the feasibility of a liposome-based therapeutic delivery system capable of delivering hydrophilic and hydrophobic therapeutics to the traumat ...

    STTR Phase I 2018 Department of DefenseDefense Health Agency
  3. Medical Device to Assess the Viability of Tissue Prior to Skin Grafting

    SBC: Spectral Md, Inc.            Topic: DHP17A006

    The primary objective of this Phase II proposal is to construct and validate the portable SpectralMD DeepView imaging technology designed previously in Phase I. This device allows surgeons to quickly and objectively assess tissue viability in burn surgery prior to skin grafting. DeepView uses machine learning and multispectral imaging to generate quantitative prognostic images with easily interpre ...

    STTR Phase II 2018 Department of DefenseDefense Health Agency
  4. Smart Morphing Moulage Medical (SM3) Training Platform

    SBC: Luna Innovations Incorporated            Topic: DHA17A002

    Medical moulage is used in medical training to simulate injuries or pathologies, however current moulage is static and does not provide the trainee feedback on the quality of care or ultimate outcome of that care. Allowing a trainee to witness the injury or pathology -morph- while treatment is being provided can provide feedback on any potential mistreatment and enhance the learning and proficienc ...

    STTR Phase I 2017 Department of DefenseDefense Health Agency
  5. Electrotextile Systems for Human Signatures Monitoring

    SBC: Mantel Technologies, Inc.            Topic: DHA17A001

    Investments by the Department of Defense (DOD) have led to the development and demonstration of electronic textiles capable of transforming traditional textile systems into wearable power and data systems. The Defense Health Agency (DHA) has identified an opportunity to leverage advancements in smart garment systems for military personnel to aid in the prediction in performance declines and healt ...

    STTR Phase I 2017 Department of DefenseDefense Health Agency
  6. Non-invasive Telemetric Assessment of Gut Microbiota Activity in Situ

    SBC: NANOHMICS INC            Topic: DHA17A004

    Physical, mental, and environmental stress, as well as diet and hydration have an impact on overall health, performance, and well-being of humans. These factors all affect the composition and metabolism of the microbiota in the gastrointestinal (GI) tract. The mix of microorganisms in the gut, and their metabolic transformation of food, can alter the overall health and physiology of the host. Me ...

    STTR Phase I 2017 Department of DefenseDefense Health Agency
  7. Medical Device to Assess the Viability of Tissue Prior to Skin Grafting

    SBC: Spectral Md, Inc.            Topic: DHA17A006

    The primary objective of this proposal is to design and demonstrate the SpectralMD DeepView imaging technology can allow surgeons to quickly and objectively assess the viability of tissue in a burn excision site prior to skin grafting. DeepView uses machine learning algorithms to analyze data acquired by multispectral imaging to generate quantitative prognostic images with a user-friendly output t ...

    STTR Phase I 2017 Department of DefenseDefense Health Agency
  8. Developing Software for Pharmacodynamics and Bioassay Studies

    SBC: TConneX Inc.            Topic: DHP16C001

    Estimation of the primary parameters like IC 50 in traditional dose-response modelsmay fail or lead to misleading results when the observations are non-onotonic due to drugresistance or virus mutation in various biomedical lab research. The objective of this project isto develop a novel approach to assess dose response relationship, which is applicable to generalpharmacologic, toxicologic, or othe ...

    STTR Phase I 2017 Department of DefenseDefense Health Agency
  9. Passive Pneumatic Prosthetic Ankle with Biomimetic Response

    SBC: ADA TECHNOLOGIES INC            Topic: DHP16C007

    The Defense Health Program seeks to improve the lives of service members suffering below knee amputations through the development of a non-powered lower extremity prosthesis designed to restore range of motion and power generation to that of an uninjured anatomical ankle. Current passive systems are still in early stages of development and typically only address one aspect of what the Defense Heal ...

    STTR Phase I 2017 Department of DefenseDefense Health Agency
  10. Universal Plasma Generator for Selective Removal of Anti-A and Anti-B Antibodies from Donor Plasma

    SBC: LYNNTECH INC            Topic: DHP15B001

    Traumatic injury accounts for 14.2% of all fatalities. Clinical management of trauma often requires massive plasma transfusions. However, in critical combat casualty care or in civilian emergency trauma care, plasma of compatible blood group may not be readily available. Transfusion with incompatible plasma may result in potentially fatal hemagglutination in the recipient. Typeless or universal pl ...

    STTR Phase II 2017 Department of DefenseDefense Health Agency
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