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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Smart Membranes for Biomolecular Detection

    SBC: 20 20 Genesystems Inc            Topic: N/A

    DESCRIPTION (provided by applicant): The main objective of this project is to develop membranes with surfaces tailored for specific affinity for a particular protein or nucleic acid molecule. These 'smart' membranes will be used in the next generation of high throughput Layered Expression Scanning (LES) applications, such as tissue screening and analytical blotting (northern and western). The hear ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  2. Incorporating Bone Minerals into Orthopaedic Surfaces

    SBC: ADVANCED SURFACES AND PROCESSES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Submerged Electro-Spark Deposition (SESD, US patent pending), developed at Advanced Surfaces And Processes, Inc., is a surface modification technique. Any conductive surface can be modified with regards to surface texture and chemical composition. The objective of the present proposal is to use SESD to incorporate appreciable amounts of bone mineral elements, i ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  3. COSMOBOING! THERAPEUTIC EXERCISE SYSTEM

    SBC: Anthrotronix, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term goal of the CosmoBoing! Therapeutic Exercise System is to develop a child-friendly, engaging tool for assuring that children with disabilities participate in and benefit from prescribed therapeutic exercise. The system will serve two populations of children. The first group is comprised of children with acquired and developmental disabilities who ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  4. Morpholino Antisense Drugs for Hepatitis C Virus

    SBC: Avi Biopharma, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Hepatitis C Virus (HCV) causes a persistent infection in most humans exposed to the virus. HCV infection in time can lead to cirrhosis and hepatocellular carcinoma. Although the annual number of newly infected patients has dropped significantly over the past decade, about 4 million people are currently persistently infected in the USA. There is presently no un ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  5. Bioscience Research Integration Software Platform

    SBC: BIOFORTIS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The need to investigate and understand all elements of biological information pertinent to disease is more clearly evident now than ever before. However, the avalanche of non-integrated data produced by today's technologies prevents scientists from effectively reducing these data to meaningful discoveries. As a result, the vast bulk of data collected through ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  6. Feasibility Evaluation of a Prosthetic Venous Value

    SBC: BIOMEDICAL RESEARCH ASSOCIATES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this Phase I STTR proposal is to demonstrate the feasibility of a novel prosthetic venous valve design concept. One of the ultimate goals in vascular surgery is to develop a successful prosthetic venous valve to replace defective valves in patients with chronic venous insufficiency (CVI). More than 8 million Americans suffer from the debilitating c ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  7. Thromboresistant vascular grafts:heparin-peptidomimetics

    SBC: BIOSURFACE ENGINEERING TECHNOLOGIES            Topic: N/A

    Thrombosis of synthetic vascular grafts is a major problem with current grafts that necessitates prophylaxis, can lead to loss of patency with an attendant need for repeat surgery, and comes with a high risk of limb loss. The applicant proposes to develop thromboresistant extended polytetrafluoroethylene (ePTFE) vascular grafts that use an absorbed coating of heparin to control acute and subacute ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  8. Cord Blood Cells in ALS: Replacement of Protection?

    SBC: SANERON CCEL THERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Amyotrophic lateral sclerosis (ALS) is a fatal degenerative disease affecting motor neurons in the spinal cord, brainstem and cortex. We have previously shown that transplanting neuronal cells into the spinal cord delays the onset of motor symptoms in the G93A mouse model of ALS, but developing a potential treatment strategy around a committed neuronal cell or ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  9. Protection from hearing loss using calpain inhibitors

    SBC: CEPTOR CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): In recent years, progress towards elucidating the molecular and cellular basis of neurodegeneration has accelerated due to our greater understanding of the role of proteases in degenerative conditions. In particular, the combined effect of increased intracellular Ca ++coupled to activation of calpains, intracellular proteases, in disorders such as stroke, ALS, ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  10. Development of new inhibitors of androgen receptors

    SBC: Cleveland Biolabs, Inc            Topic: N/A

    DESCRIPTION (provided by applicant): This program is aimed at developing a new class of drugs effective against most aggressive and a poorly curable hormone independent form of prostate cancer (CAP). Failure of androgen ablation therapy is rarely associated with the loss of the androgen receptor (AR) signaling by hormone-independent CaP. AR pathway in such tumors remains constitutively active rega ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
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