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The Award database is continually updated throughout the year. As a result, data for FY21 is not expected to be complete until September, 2022.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. A2A receptor blockade for sepsis

    SBC: Purine Pharmaceuticals Inc.            Topic: NIAID

    SUMMARY Sepsis is a clinical syndrome that complicates severe infectionSepsis remains the leading cause of morbidity and mortality in critically ill patientsThere are no specific FDA approved medicines for the treatment of sepsisCurrent concepts of the pathophysiology of sepsis suggest that organ failure and mortality in sepsis are caused by inappropriate regulation of the immune systemThis manife ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Accelerating Metagenomics Using Graphics Processing Units

    SBC: Multicoreware, Inc.            Topic: 35a

    A key application of the technological breakthrough associated with decreased cost of DNA sequencing is metagenomics. Metagenomics is the process of sequencing DNA from whole ecosystems, rather than individuals or cultures. This approach has the potential to allow the dissection of microbial ecosystems in biofuel producing agricultural land, toxic contaminated sites and hydrocarbon recovery enviro ...

    STTR Phase I 2010 Department of Energy
  3. AC5 Inhibitor for Obesity

    SBC: VASADE BIOSCIENCES, INC.            Topic: NIDDK

    DESCRIPTION (provided by applicant): The goal of this proposal is to develop a drug that will be therapeutic for obesity and diabetes and improve exercise tolerance. Obesity, diabetes and exercise are inextricably linked such that an agent that improves exercise tolerance or prevents obesity or the development of diabetes will likely have a therapeutic role in all three conditions. Obesity is a gl ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  4. A Cognitive Communications Protocols Suite for Networked Space Platforms for Autonomous Dynamic Spectrum Co-existence with User-Initiated Service Support

    SBC: Bluecom Systems And Consulting LLC            Topic: T5

    The STTR topic T5.01 envisions Autonomous Communications Systems (ACS) that can be aware of RF environment and the network status and learn from experience to enhance adaptability to nominal/anomalous conditions, self-reconfigure network connections, dynamically maximize performance in response to sensed conditions and mitigate system-level effects of outages and interference. In Phase II, Bluecom ...

    STTR Phase II 2019 National Aeronautics and Space Administration
  5. A cost-effective bioreactor to advance functional tissue engineering of cartilage

    SBC: Apex Biomedical Company, LLC            Topic: NIAMS

    DESCRIPTION (provided by applicant): Osteoarthritis (OA) is the leading cause of chronic disability in the United States. A clinical goal in the treatment and prevention of OA is to develop replacement cartilage using tissue engineering (TE) technologies. Although TE cartilage presently lacks the mechanical stability of native cartilage, studies have demonstrated that mechanical stability can be e ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  6. Acoustic Intercept Receiver for Naval Special Warfare Undersea Vehicles

    SBC: Information Systems Laboratories, Inc.            Topic: N09T012

    Information Systems Laboratories (ISL) and Florida Atlantic University (FAU) propose to develop and test a system that uses existing signal processing algorithms coupled with innovative construction technology developed ISL under our E-Field sensor programs and FAU under UUV programs. The Challenge is to develop a small system package with the capability to intercept active threat emissions early ...

    STTR Phase II 2010 Department of DefenseNavy
  7. Acute-infarct selective cardiac MRI contrast agent

    SBC: ELGAVISH PARAMAGNETICS, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant The overall goal of this project is to demonstrate the ability of our acute myocardial infarct selective paramagnetic contrast agent Gadolinium ABE DTTA to differentiate between acute and chronic infarcts in a reliable manner using contrast enhanced magnetic resonance imaging ceMRI In our Phase I data we have shown that Gd ABE DTTA exclusively highlight ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  8. Adaptive and Smart Materials for Advanced Manufacturing Methods

    SBC: Nextgen Aeronautics, Inc.            Topic: AF17AT018

    The focus of this STTR program is the development and maturation of a novel, room-temperature process to fabricate multi-layer metal-polymer (including PVDF and other smart materials) composites in an additive approach. This overcomes the limitation arising from the large temperature difference between metal and polymer manufacturing processes, and presents a new technology for additive manufactur ...

    STTR Phase II 2019 Department of DefenseAir Force
  9. Adaptive Fleet Synthetic Scenario Research

    SBC: KAB LABORATORIES INC.            Topic: N10AT044

    Synthetic scenario-based training of Navy personnel in the use of Navy SIGINT/IO systems has helped to reduce training costs, and it has enabled the personnel to be trained in an environment that sufficiently approximates real-world situations that could not otherwise be accomplished within the class room. However, scenario development is highly complex and involves a great deal of human effo ...

    STTR Phase I 2010 Department of DefenseNavy
  10. Adaptive Integrated Multi-Modal Sensing Array

    SBC: Polaris Sensor Technologies, Inc.            Topic: AF08BT02

    Nanoscale infrared detectors are emerging as a potentially powerful alternative to traditional infrared detector technologies. The University of New Mexico has developed dots in a double well (DDWELL) quantum dot infrared photodetectors which have a spectral responsivity that can be tuned by controlling the bias voltage applied. In this Phase II effort, Polaris Sensor and UNM would fabricate a g ...

    STTR Phase II 2010 Department of DefenseAir Force
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