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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Completion of IND-package for a novel, non-narcotic painkiller
SBC: BLUE THERAPEUTICS, INC. Topic: NIDAProject Summary Opioids like morphine and hydrocodone are generally the most effective therapeutics for treatment of moderate to severe pain. However, their use is limited by serious side effects - tolerance, constipation, respiratory depression, physical dependence and high addictive potential. The frequency of clinical pain, coupled with a lack of alternative therapeutic options has led to a nat ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
IGF::OT::IGF TOPIC 378: SYMPTOMATIC TOXICITY MOBILE MONITOR (SYMPTMM)
SBC: VIVONICS INC Topic: NCIThe goal of this NIH Phase I SBIR proposal is to develop and validate a new method to monitor the symptomatic toxicities and health related quality of life of cancer patients who are undergoing and have undergone radiation therapy during the course of their treatmentThe proposal is built around expertise in mobile application developmentVivonics Incand radiation oncologyDrTJ Fitzgerald of the Univ ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
SBIR TOPIC 108, FAST-TRACK- DEVICE SYSTEM FOR TRANSCATHETER REPAIR OF POSTINFARCTION VENTRICULAR SEPTAL DEFECT
SBC: TRANSMURAL SYSTEMS LLC Topic: NHLBIThe goal of the project is to develop a device for percutaneous closure of postinfarction ventricular septal defectVSDin adultsFirst a prototype would be developed and tested in animalsand ultimately a clinical grade device would undergo regulatory developmentPhase I will include the development and testing of a postinfarction VSD occluder prototypePhase II will include mechanical and safety testi ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
SBIR TOPIC 106, FAST-TRACK- ACTIVE MRI NEEDLE
SBC: TRANSMURAL SYSTEMS LLC Topic: NHLBINeedle access to deep organs is common to numerous catheterradiologicaland surgical proceduresboth diagnostic and therapeuticincluding access to blood vesselspericardial and cardiac chambersvisceraetcMRI operation affords exquisite imaging and delineation of soft tissue beyond what is afforded by X ray fluoroscopyCTand ultrasound guidancePassiveneedles visualized solely by their material propertie ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
SBIR TOPIC 104, FAST-TRACK, TAPERED GUIDEWIRES FOR TRANSCATHETER ELECTROSURGERY
SBC: TRANSMURAL SYSTEMS LLC Topic: NHLBIThe contractor will develop specific guidewire devices to ease and simplify transcaval access to the aortato make the procedure available to a wider range of patients and operatorsThe goal is to develop a tapered guidewire and a connector switch to a common electrosurgery generator to simplify transcaval access to the aortaUnder Phase I the contractor will develop and test a suite of working proto ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
SBIR TOPIC 107, PHASE I- TRANSCATHETER POTTS SHUNT
SBC: TRANSMURAL SYSTEMS LLC Topic: NHLBIThe goal of Phase I is to develop and test a Transcatheter Potts Shunt prototype system in vivoThe deliverable is a catheter system to establish a non surgical Potts Shunttranscatheter pulmonary to aortic anastomosisto treat refractory pulmonary artery hypertensionPhase I will focus on mechanical and biological performance of the proposed endografttaking into account mechanical strength required f ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Nanoparticle Delivery of HIV Env Trimer for Inducing Somatic Hypermutation and bNAb
SBC: ANTAGEN BIOSCIENCES INC Topic: NIAIDHIVthe virus that causes AIDSis one of the world s most serious health challengesAccording to UNAIDSthere were approximatelymillion people worldwide living with HIV AIDS at the end ofThe vast majority of them are in lowto middle income countriesparticularly in sub Saharan AfricaA low cost vaccine broadly neutralizing most strains of HIV is the preferred response to protect the human populationHowe ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
A Smartphone-based point-of-care Sensor for Rapid and Sensitive Detection of Malaria in Low-Resource Applications
SBC: GINER INC Topic: NIAIDThe wide availability of rapidfield portablelow costand sensitive molecular diagnostic for point of care detection of malaria parasites would have a significant benefit for intervention programs aimed at eliminating malaria in affected populationsMalaria remains one of the most serious infectious diseases in low income countriesthreatening nearly half of the world s population and causing an estim ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
SBIR PHASE II: LABHAND PAYLOAD FOR INSTANTEYE SUAS PLATFORM FOR CONTINUOUS AUTONOMOUS INDOOR TRANSPORT OF LABORATORY CONSUMABLES
SBC: PHYSICAL SCIENCES INC. Topic: NIDAThe objective of this Phase II SBIR contract and subsequent Phase III effort is to develop and commercialize acompleteautonomous drone based system for moving microplatesand similar lab consumableswithin HighThroughput ScreeningHTSlaboratoriessupplementing and perhaps eventually replacing robotic arms whichcurrently perform HTS autonomous processing of samplesThis innovative application of smallau ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
TOPIC 386: NOVEL ORALLY BIOAVAILABLE PDE-CATENIN INHIBITOR CONCENTRATES IN LUNG FOR CANCER CHEMOPREVENTION
SBC: ADT Pharmaceuticals, LLC Topic: NCIThis application is based on ADT Pharmaceuticalsdiscoveries thatthe cGMP degrading phosphodiesterase isozymephosphodiesteraseAPDEis overexpressed during early stages of tumorigenesisgenetic knockdown of PDEresults in selective apoptosis of tumor cells by activating cGMP PKG signalingandsmall molecule inhibitors of PDEinduce apoptosis by PKG phosphorylation of oncogeniccateninthereby suppressing Tc ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health