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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Extended Release of Pyridostigmine Bromide for Effectively Combating Nerve Agent Exposure

    SBC: Innosense Llc            Topic: CBD181004

    Chemical warfare agents such as the lethal nerve agent soman are a major source of risk to military personnel. Currently, pyridostigmine bromide (PB) is the only FDA-approved pretreatment to counteract the effects of soman. The rationale behind PB administration is that it acts as a “temporary” inhibitor of AChE. This precludes nerve agents from irreversible inactivation of AChE, thereby mitig ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  2. Dual Formulation of Atropine/Scopolamine with Enhanced Stability

    SBC: Cmc Pharmaceuticals, Inc.            Topic: CBD181005

    CMC Pharmaceuticals, Inc. (Cleveland, OH) is proposing developing a stable, combination product of two small molecule drug candidates as a counter measure to chemical warfare nerve agents (NA). The combination product is expected to exploit complementary pharmacological profiles for optimal muscarinic receptor blockade and anticholinergic activity within the peripheral and central nervous system. ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  3. Sequential Phase II Proposal for Smartphone Application for Mask Sizing and Projecting Quantitative Fit

    SBC: Physical Optics Corporation            Topic: CBD181006

    To address the Chemical and Biological Defense (CBD) need for a field-portable mass spectrometer for small molecule drugs in clinical samples, Physical Optics Corporation (POC) proposes to develop a new FiEldable DRug Mass Analysis (FERMA) system based on a combination of portable mass spectrometry technology with laser desorption/ionization for use with aqueous clinical samples. The FERMA system ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  4. Field Portable Mass Spectrometry for Small Molecule Drugs in Clinical Samples

    SBC: Spectral Energies, LLC            Topic: CBD181006

    We propose a novel two-dimensional mass spectrometry (2D-MS) technique based on ion trap arrays to identify illicit and designer drugs. This approach will give an unprecedented multiplex advantage for miniature mass spectrometry, allowing novice field technicians to rapidly identify drugs affecting the central nervous system based on both the m/z ratio and fragmentation pattern of an ion. Towards ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  5. SWAT- Scalable W(R)ubber through Advanced Technology

    SBC: EnergyEne Inc.            Topic: ST18C001

    Opportunity: Guayule, a US native plant, is the only alternate rubber crop with an established, mechanized, agronomic system. Problem: Low rubber yields and lack of effective resin and bagasse coproduct valorization, have prevented widespread adoption by American farmers and processors. Rubber is only made when the cytoplasmic monomer pool (isopentenyl-pyrophosphate; IPP) is larger than that requi ...

    STTR Phase I 2019 Department of DefenseDefense Advanced Research Projects Agency
  6. Development of Autonomous Glycemic Control Mechanism for Patients Suffering Glycemic Abnormalities as a Result of Critical Illnesses

    SBC: PROFUSA, INC.            Topic: ST18C004

    The use of continuous glucose monitors can be an invaluable management tool for patients afflicted by glycemic variability due to critical illness or trauma. Maintaining stable glucose levels enhances health and lowers care costs, and individuals equipped with continuous glucose data have significantly improved outcomes. Profusa has developed highly miniaturized, injectable, tissue-like, glucose s ...

    STTR Phase I 2019 Department of DefenseDefense Advanced Research Projects Agency
  7. Visual Relative Navigation via Intelligent Ephemeral Relationships (VRNIER)

    SBC: TOYON RESEARCH CORPORATION            Topic: ST18C006

    As unmanned aircraft systems (UAS) become more prevalent there is an increasing desire to automate UAS navigation and control. To enable future UASs to perform a wider variety of missions, the they must be able to complete autonomous relative navigation to accomplish missions. Current technologies rely heavily on GPS measurements, which are undesirable since GPS signals may be unavailable in many ...

    STTR Phase I 2019 Department of DefenseDefense Advanced Research Projects Agency
  8. Ocular Penetrating/Perforating injuries Assessment Hydrogel system (OPPAH)

    SBC: Chromologic LLC            Topic: DHP182004

    In order to meet Defense Health Agency’s need for rapid confirmation and evaluation of open globe injuries, to allow for appropriate initial triage, evacuation, and treatments, ChromoLogic LLC (CL) proposes to develop an Ocular Penetrating/Perforating inj

    SBIR Phase I 2019 Department of DefenseDefense Health Program
  9. Cervical Spine Health Improvement Products

    SBC: Switchbox, Inc.            Topic: DHP18B001

    Most standard-of-care tools and techniques for evaluating neck disorders are subjective, unreliable, and do not provide actionable information for providers, payers, and organizations to deliver efficient and effective care. This lack of objective neck he

    STTR Phase I 2019 Department of DefenseDefense Health Program
  10. Augmented Reality Surgical Visualization

    SBC: CFD Research Corporation            Topic: DHP191001

    Care for the wounded Warfighters in austere and remote settings makes medical knowledge, skills and efficiency of the military medical professional paramount. For wounds that extend deep into internal anatomy, proper visualization of internal anatomy can

    SBIR Phase I 2019 Department of DefenseDefense Health Program
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