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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. BurntOut: Role-Play Simulation for Building Medical Student Resiliency

    SBC: Clinical Tools, Inc            Topic: 400

    PROJECT DESCRIPTIONBurntOut: Role-Play Simulation for Building Medical Student Resiliency Medical student and physician burnout rates are high. Rates correlate with alcohol and other substance use problems, and negatively impact patient care. This project will create a 3D simulation BurntOut: Role- Play Simulation for medical students to practice and respond to stressful situations, enhance coping ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  2. A Quality Control Program for Quantitative MRI DataAcquisition and Analysis in Multi-site Clinical Trials

    SBC: CaliberMRI, Inc.            Topic: 101

    Project Summary/Abstract There has been a shift to greater use of neadjuvant chemotherapy (NACT) in the clinical management of cancer. Often used in breast cancer to provide systemic treatment for possible or apparent metastatic disease, NACT also reduces the primary tumor size and facilitates breast conservation. Quantitative magnetic resonance imaging (qMRI) is an effective diagnostic for monito ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Novel assay to monitor Tacrolimus levels at the point of care

    SBC: AFFINERGY, LLC            Topic: NIAID

    SUMMARY/ABSTRACT In 2016, over 33,000 organ transplants were performed in the United States, an increase of 20% over the past 5 years. Organ transplantation requires lifelong immunosuppression to prevent rejection of the transplant. Tacrolimus, a macrolide antibiotic, is one of the most effective immunosuppressants, with andgt;90% of solid organ transplant recipients receiving it as part of their ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Development of an oral therapeutic to mimic the anti-diabetic effects of gastric bypass surgery

    SBC: BIOKIER, INC.            Topic: 200

    SUMMARY Glucose homeostasis and food intake are both regulated by gut hormones secreted from enteroendocrine L- cells in the lower gut following stimulation by nutrients. This process is impaired in diabetes but is restored with delivery of dietary nutrients such as amino acids and fatty acids to the lower gut, such as after gastric bypass surgery and during fermentation of carbohydrates in the co ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Development of Novel Compounds for Treatment of Heart Arrhythmias in CPVT

    SBC: Elex Biotech, Inc            Topic: NHLBI

    PROJECT SUMMARY The goal of this project is to complete the preclinical development of Elex Biotechandapos;s novel compounds that target and treat the underlying molecular cause of catecholaminergic polymorphic ventricular tachycardia (CPVT) CPVT. There are no FDA-approved treatments for CPVT, a rare genetic disorder affecting 1/10,000 individuals, with typical onset in children 7-9 years of age a ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Development of a novel clinical assay for measuring everolimus levels

    SBC: AFFINERGY, LLC            Topic: NIAID

    SUMMARY/ABSTRACT In 2017 nearly 35,000 solid organ transplants were performed in the United States, an increase of 27% over the past ten years. Organ transplantation requires lifelong immunosuppression to prevent rejection of the transplant. Many new classes of drugs have been developed to combat the side effects and interactions common to immunosuppressants, with several agents (sirolimus, everol ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  7. New Class of Bright, Sharp, Tunable Near-Infrared Fluorophores for Flow Cytometry

    SBC: Nirvana Sciences, Inc.            Topic: NIAID

    Abstract Polychromatic flow cytometry (FC) is one of the most powerful analytical techniques routinely used by both basic research and clinical diagnostics laboratories for the immunological categorization of cells. Dyes used for FC typically exhibit broad fluorescent emission bands with full-width-at-half-maximum (fwhm) values of 50–80 nm. This limits the maximum number of dyes, and thus the nu ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Reducing HIV Health Disparities among African American Transgender Women: An mHealth Approach to Improving Prevention, Testing, and Treatment Outcomes

    SBC: ISA ASSOCIATES INC            Topic: 105

    PROJECT SUMMARY/ABSTRACTOne in five transgender women (TGW) in the U.S. is infected with HIV. The burden is particularly onerous for African Americans. While 16% of U.S. TGW are Black, over half of all new cases in TGW from 2009-2014 were among African Americans. Further, African American TGW experience a complex interaction of racism, sexism, and transphobia that leads to health disparities acros ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Clinical Evaluation of Biocompatible Dressings for the Delivery of Analgesics

    SBC: Keratin Biosciences Inc.            Topic: A14048

    The Phase I and Phase II projects that are the basis for this Phase II enhancement proposal tested the feasibility of releasing opiate compounds from a topical wound dressing for burn pain relief and treatment. This project culminated with a regulatory s

    SBIR Phase II 2019 Department of DefenseDefense Health Agency
  10. Modular Biosensor Patch

    SBC: Cornerstone Research Group, Incorporated            Topic: DHA18003

    Researchers are identifying new biomarkers to help monitor cognition and stress in the human body and enhance human performance. Traditional biomarkers like heart rate, temperature, oxygen saturation, blood glucose, electrolyte concentration, etc have bee

    SBIR Phase II 2019 Department of DefenseDefense Health Agency
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