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A key application of the technological breakthrough associated with decreased cost of DNA sequencing is metagenomics. Metagenomics is the process of sequencing DNA from whole ecosystems, rather than individuals or cultures. This approach has the potential to allow the dissection of microbial ecosystems in biofuel producing agricultural land, toxic contaminated sites and hydrocarbon recovery enviro ...

As computational density for high-performance computing and big-data services continues to scale, performance scalability of next generation computing systems is becoming increasingly constrained by limitations in memory access, power dissipation and chip packaging. The processor-memory communication bottleneck, a major challenge in current multicore processors due to limited pin-out and power bud ...

Coal is an abundant source of energy in the USA, but is not currently utilized effectively. Recently, the DOE has begun a carbon sequestration program is to develop advanced CO2 capture and compression technology for existing coal-fired plants with increased efficiency with no more than a 35% increase in the cost of electricity. This will require new approaches and technologies to be successful. N ...

For this Phase I SBIR proposal, Vcom3D proposes to design advanced medical moulage that accurately simulates the progression of an injury or pathology by morphing through a series of clinical states to enable learners to confirm the progression of the wound and to determine whether iatrogenic errors or pathologies occurred duing treatment. The physical morphing moulage may be applied to medical m ...

The Exascale Computing Project is tasked to develop the next generation of high performance computing systems capable of computing at 50 to 100 times faster than current HPC systems. Computing at this extreme-scale will significantly enhance the value of materials modeling and simulation to basic materials research and engineering In particular, computing at the extreme scale will enable a higher ...

The problem being addressed is the development of high intensity ultrashort pulse lasers, in recognition that today’s ultra-high intensity lasers are limited to repetition rates of < 10 Hz. Technical solutions are sought to enable the generation of high energy (joule-level) laser pulses that can be focused to highly relativistic intensity at high repetition rates (100-1000 Hz). The proposed proj ...

Computer-aided Engineering software that apply the Finite Element Method to perform a multi-physics analysis have received widespread acceptance for traditional macro-scale material systems. Challenges persist in the modeling of complex coupled processes in environmental/thermal barrier coatings (E/TBCs) used to protect substrate material against the corrosive environment in the hot section parts ...

Separations often account for a majority of process costs. This is because all traditional separation processes have inherent weaknesses that prevent the system from achieving perfect (or even near perfect in many instances) selectivity. These weaknesses result in large recycle streams and require multiple separation units in concert in order to produce a product clean enough for use or sale. An a ...

Diversifying and providing biobased alternatives to products from oil are critical for increasing U.S. energy security, developing a clean energy security and creating domestic jobs. Diols are a class of chemicals used by the chemical industry to produce polyester polyol polymers and polycarbonate diols, which are used in the manufacture of plastics, paints, coatings and adhesives. Currently, all ...

Electrons play a very key role in plasma chemistry and dynamics of low temperature plasmas. Improved capability for measuring electron number density, ne, and electron energy distribution function, EEDF, in weakly ionized low temperature plasmas would benefit both fundamental study and application areas. For example, the capability would directly benefit emerging research targeted at modifying and ...