Award Data

This NASA sponsored STTR project will investigate methods for close-out of large, liquid rocket engine, nickel or stainless steel nozzle, coolant channels utilizing robotic laser and pulsed-arc additive manufacturing (AM)methods. Structural jacket to coolant channel land area interface strength will be quantified and metallurgical characterization completed.Process optimizations will be conducted ...

To address the urgent need for 3D flash-lidar technology for landing on solar system bodies and for spacecraft rendezvous and docking with satellites, an effort is proposed to fabricate, characterize, and test a versatile, high-sensitivity InGaAs APD 3D flash lidar and to advance the technology-readiness level (TRL) of lidar technologies suitable for NASA mission requirements. Leveraging an existi ...

The problem addressed in this effort is to automatically learn historical ephemeris space catalog time, position, and velocity entity track update error uncertainties (i.e., without track error covariances) and to automatically (e.g., without expert event labeling) produce: – unmodeled non-gravitational space catalog update flags – abnormal unmodeled catalog update flags with abnorma ...

IFOS is developing a multifunctional whole-blood analysis lab-on-a-chip platform for assessment of kidney health. The IFOS innovations are found in each subsystem, including photonic integrated circuits (PICs), microelectronics, and biochemical microfluidics. The unique differentiated design is expected to result in a low SWaP-C, highly manufacturable, and highly reliable on-demand measurement pla ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase II project is the development of software to help bioscientists analyze more tissue in less time and with higher accuracy and reproducibility. Currently, stereology studies require a trained technician to sit before a computer screen, making tedious manual counts (clicks) on hundreds to thousands of mic ...

PROJECT SUMMARY Thehemoglobinopathies are prevalent genetic blood diseases with few treatment optionsIt is estimate thatof the worldandapos s population carries an abnormal hemoglobin gene withinfants born annually with a severe life threatening hemoglobinopathyDrug mediated induction of normalbut developmentally silencedfetal hemoglobinHbFexpression reduces anemia and ameliorates clinical severit ...

Compatibility Between Brain Computer Interface and High Efficiency Augmentative and Alternative Communication SystemsPhase II ABSTRACTBrain computer interfacesBCIenable text production for people who cannot movebut have only simple communication interfaces and are not widely usedAugmentative and alternative communicationAACsystems are widely used and give efficient and precise communicationbut req ...

Ischemic stroke is a leading cause of death and disability in the United StatesThis often is attributable to thrombus formation at an atherosclerotic plaque or thromboembolismPatients who present withinhours of symptom onset are eligible for thrombolysis with tissue plasminogen activatortPAThis serves andltof victimsRecentlymajor advance has been made with proven efficacy from endovascular mechani ...

PROJECT SUMMARY Migraine is a highly prevalent condition with an extraordinarily negative impact on quality of life and represents a heavy socioeconomic burden to the societyprimarily because of decreased working efficiency and workdays lostManagement of migraine has become increasingly pharmacological during recent yearsWhile several therapeutic options existmost of the prophylactic drugs current ...

PROJECT SUMMARY Traumatic brain injuryTBIrepresents a significant societal and economic impactTo datethere are no FDAapproved pharmacotherapies to prevent or reverse TBIThe standard of care in an emergency setting focuses first on stabilizing the patient and secondly on management of cerebral hemodynamicsThe patient may undergo surgery to remove hematomasrepair skull fracturesand relieve intracran ...