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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Biological Activity Assay and Bioanalytical Test Method Development for a Silk-Derived Protein (SDP) Eye Drop Product

    SBC: SILK TECHNOLOGIES, LTD.            Topic: NonDoD

    The company has developed a silk-derived protein (SDP) for use as a novel ophthalmic formulation excipient that will help to treat the ocular injuries and dry eye pathology that affects over 40 million Americans annually and hundreds of millions of people worldwide. The SDP excipient is designed to enhance tear formulation comfort, longevity, and overall ocular health. This proposal builds on the ...

    SBIR Phase II 2019 Department of DefenseDefense Health Agency
  2. Person-Centered Planning ToolKit: Development of an Application to Improve Workforce Participation Through Team Collaboration and Customized Employment Discovery Technology

    SBC: ASSISTECH SYSTEMS LLC            Topic: Disabilities

    This project addresses the need for increased opportunities for customized employment for individuals with cognitive disabilities by developing the Person-Centered Planning ToolKit. The Toolkit will enhance implementation of personcentered planning (PCP), often limited by lack of follow-through on action items and a lack of tools to match career preferences to specific customized employment opport ...

    SBIR Phase I 2019 Department of Health and Human ServicesAdministration for Community Living
  3. TRACK (Tools for Reading to Acquire Content Knowledge): An Intelligent Application for Middle and High School Students with Neurodevelopmental Disorders.

    SBC: COGMETRIC LLC            Topic: NA

    This project develops and evaluates an intelligent web-based application, Tools for Reading to Acquire Content Knowledge (TRACK) for middle and high school students with neurocognitive deficits such as individuals with learning disabilities, attention deficit/hyperactivity disorder, traumatic brain injury, or autism spectrum disorder. Applying a participatory action research approach, investigator ...

    SBIR Phase I 2019 Department of Health and Human ServicesAdministration for Community Living
  4. THIS SBIR PHASE I CONTRACT IS FOR A WEARABLE ALCOHOL BIOSENSOR THAT QUANTIFIES BAC IN REAL TIME.

    SBC: DeLeon, Augustina S            Topic: NIAAA

    Technology validation study of a wearable NIR spectrometer to quantify BAC in real time

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Electrochemical aptasensor for Anti-Tuberculosis antibiotic quantification

    SBC: GUILD ASSOCIATES INC            Topic: NIAID

    Specific AimsIn Phase I of this SBIRwe will complete three specific aimssynthesize stable combination adjuvant formulations that are compatible with an HVLP antigenidentify the combination adjuvant properties that augment the safe and durable immunity to Handdemonstrate the superior protective benefit of the new combination adjuvant over existing adjuvant solutions for pandemic influenza vaccinesI ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Multifunctional Cold Chain Container for Unmanned Aerial Vehicle Transport

    SBC: BLOODSTONE DIVISION LLC            Topic: ODCDC

    Development of an agile device that can deliver supplies to and from remote locations during public health emergenciesIn the context of emergency public health responsedrones could be extremely useful for transporting necessary supplies to remote or inaccessible locationsSupplies might include dry goodsbut would certainly include clinical specimensreagent kitsvaccines and other perishable goodsThe ...

    SBIR Phase I 2019 Department of Health and Human ServicesCenters for Disease Control and Prevention
  7. TOPIC 386: NOVEL ORALLY BIOAVAILABLE PDE-CATENIN INHIBITOR CONCENTRATES IN LUNG FOR CANCER CHEMOPREVENTION

    SBC: ADT Pharmaceuticals, LLC            Topic: NCI

    This application is based on ADT Pharmaceuticalsdiscoveries thatthe cGMP degrading phosphodiesterase isozymephosphodiesteraseAPDEis overexpressed during early stages of tumorigenesisgenetic knockdown of PDEresults in selective apoptosis of tumor cells by activating cGMP PKG signalingandsmall molecule inhibitors of PDEinduce apoptosis by PKG phosphorylation of oncogeniccateninthereby suppressing Tc ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. TOPIC 396- IMAGING FOR CANCER IMMUNOTHERAPIES-MOONSHOT

    SBC: COLUMBUS NANOWORKS, INC.            Topic: NCI

    In vivo imaging of cells labeled with fluorescent nanodiamondsFNDsis a new way of monitoring immune cells during cancer immunotherapyFNDs are non toxicinfinitely photostable nanomaterials that are easily conjugated with antibodiesand emit fluorescence in the near infrared spectral regionIn this Phase I SBIRwe will use a murine melanoma model and outline a plan to use FNDs for imaging immunosupress ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. TOPIC #366- PHASE II SBIR CONTRACT- CLONOGENIC HIGH- THROUGHPUT ASSAY FOR SCREENING RADIATION MODULATION

    SBC: SUVICA INC            Topic: NCI

    Clonogenic assays measure the ability of single cells to proliferate and form a colonyThis process approximates closely the regrowth and recurrence of tumors after treatment with radiation or chemotherapyproviding an assay to screen for drugs that block this processYetclonogenic assays are labor intensive and too cumbersome for high throughout screeningHTSof compound librariesHere we propose to de ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  10. TOPIC 389- INTELLIGENT SOFTWARE FOR RADIATION THERAPY PLANNING

    SBC: RADIASOFT LLC            Topic: NCI

    Besides surgeryradiotherapy is the most effective treatment modality for localized prostate cancerThe success of radiotherapy stems from the exploit of a therapeutic window in tumor response and normal tissue tolerance which maximizes the chance of sterilizing the tumor while sparing the surrounding normal tissue from severe damageThis requires an accurate and individualized radiation dose distrib ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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