Award Data

Thegoal is to develop asoftwaretool that implementsa novelapproach applicableto fitgeneral pharmacologic, toxicology, or other biomedical data, that mayexhibita non-monotonic dose-responserelationship for which thecurrent parametricmodels fail. Thesoftwareexplores dose-responserelationships using both monotonicand non-monotonicmodels,and estimates theassociated doseresponsecurves,which can further ...

The Department of Defenseisconcerned about adverseeffects ofcircadian rhythm misalignment on sleep hygiene and well-being ofservice members and veterans who suffer from symptoms of Post-Traumatic Stress Disorder (PTSD). Intelligent Automation, Inc., University of Central Florida RESTORES center and Raytheon IDS, proposeto develop PTSD SleepAid, an end-to-end sleep treatment system that monitors an ...

Traumatic injury accounts for 14.2% of all fatalities. Clinical management of trauma often requires massive plasma transfusions. However, in critical combat casualty care or in civilian emergency trauma care, plasma of compatible blood group may not be readily available. Transfusion with incompatible plasma may result in potentially fatal hemagglutination in the recipient. Typeless or universal pl ...

To Counter Weapons of Mass Destruction (CWMD), DTRA must analyze data from numerous sources about a diverse set of technologies and activities. The extreme diversity in content and the volume of DTRAs data combine to produce one of the most challenging analysis problems in the government. The CWMD mission therefore requires deep analysis - an in-depth understanding of all available data and correl ...

The discovery and commercial development of licensed vaccines often take many years of research followed by years of pre-clinical and clinical development. We propose to assess the feasibility of using a novel irradiation-inactivation technology to develop vaccines more rapidly. The technology utilizes a manganese-peptide complex to protect antigenic proteins from ionizing radiation while allowing ...