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The Award database is continually updated throughout the year. As a result, data for FY22 is not expected to be complete until September, 2023.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Universal Plasma Generator for Selective Removal of Anti-A and Anti-B Antibodies from Donor Plasma

    SBC: LYNNTECH INC            Topic: DHP15B001

    Traumatic injury accounts for 14.2% of all fatalities. Clinical management of trauma often requires massive plasma transfusions. However, in critical combat casualty care or in civilian emergency trauma care, plasma of compatible blood group may not be readily available. Transfusion with incompatible plasma may result in potentially fatal hemagglutination in the recipient. Typeless or universal pl ...

    STTR Phase II 2017 Department of DefenseDefense Health Agency
  2. PTSD SleepAid: A Circadian Rhythm Monitoring and Regulation system for patients with PTSD

    SBC: Intelligent Automation, Inc.            Topic: A16AT014

    The Department of Defenseisconcerned about adverseeffects ofcircadian rhythm misalignment on sleep hygiene and well-being ofservice members and veterans who suffer from symptoms of Post-Traumatic Stress Disorder (PTSD). Intelligent Automation, Inc., University of Central Florida RESTORES center and Raytheon IDS, proposeto develop PTSD SleepAid, an end-to-end sleep treatment system that monitors an ...

    STTR Phase II 2017 Department of DefenseDefense Health Agency
  3. Semantic Parsing and role Labeling In Combination Effort (SPLICE)

    SBC: DECISIVE ANALYTICS CORPORATION            Topic: DTRA14B003

    To Counter Weapons of Mass Destruction (CWMD), DTRA must analyze data from numerous sources about a diverse set of technologies and activities. The extreme diversity in content and the volume of DTRAs data combine to produce one of the most challenging analysis problems in the government. The CWMD mission therefore requires deep analysis - an in-depth understanding of all available data and correl ...

    STTR Phase II 2017 Department of DefenseDefense Threat Reduction Agency
  4. Production of Inactivated Vaccines Using Supralethal Irradiation

    SBC: BIOLOGICAL MIMETICS INC            Topic: DTRA14B002

    The discovery and commercial development of licensed vaccines often take many years of research followed by years of pre-clinical and clinical development. We propose to assess the feasibility of using a novel irradiation-inactivation technology to develop vaccines more rapidly. The technology utilizes a manganese-peptide complex to protect antigenic proteins from ionizing radiation while allowing ...

    STTR Phase II 2017 Department of DefenseDefense Threat Reduction Agency
  5. Developing Software for Pharmacodynamics and Bioassay Studies

    SBC: TConneX Inc.            Topic: DHP16C001

    Thegoal is to develop asoftwaretool that implementsa novelapproach applicableto fitgeneral pharmacologic, toxicology, or other biomedical data, that mayexhibita non-monotonic dose-responserelationship for which thecurrent parametricmodels fail. Thesoftwareexplores dose-responserelationships using both monotonicand non-monotonicmodels,and estimates theassociated doseresponsecurves,which can further ...

    STTR Phase II 2019 Department of DefenseDefense Health Agency
  6. Smart Morphing Moulage Medical (SM3) Training Platform

    SBC: Luna Innovations Incorporated            Topic: DHA17A002

    Medical moulage is used in medical training to simulate injuries or pathologies, however current moulage is static and does not provide the trainee feedback on the quality of care or ultimate outcome of that care. Allowing a trainee to witness the injury or pathology -morph- while treatment is being provided can provide feedback on any potential mistreatment and enhance the learning and proficienc ...

    STTR Phase I 2017 Department of DefenseDefense Health Agency
  7. Deep Learning based Automated Ultrasonic Vocalizations Scoring: DLAS

    SBC: Intelligent Automation, Inc.            Topic: DHP16C003

    Ultrasonic vocalizations (USVs) provide an excellent behavioral measure that can be used to understand the effects of traumatic stressors on behavior and can be used to screen and identify therapeutic treatments. This provides a strong justification for the use of rodent USVs as a model for emotional processing in PTSD. Since there are no commercially available USV assessment software programs tha ...

    STTR Phase I 2017 Department of DefenseDefense Health Agency
  8. Modeling of Polytonic Dose Response Relationships

    SBC: LipoSeuticals Inc            Topic: DHP16C001

    Dose response relationships are fundamental to pharmacology and many other fields. Increasingly, scientists are encountering polytonic dose response relationships. These relationships are not well-characterized by linear and s-shaped models. Our team has extended the traditional 4 parameter logistic model by replacing the dose parameter with the quadratic function as an effective dose function. Th ...

    STTR Phase I 2017 Department of DefenseDefense Health Agency
  9. Compact Laser Drivers for Photoconductive Semiconductor Switches (16-RD-863)

    SBC: UES INC            Topic: DTRA16A004

    Compact Electromagnetic Pulse Module (EMP) capable of being arranged in series-parallel planar or cylindrical arrays is needed to simulate nuclear weapon effects. High gain optically triggered photoconductive semiconductor switches (PCSS) based on Gallium arsenide (GaAs) with low timing jitter enables the development of planar or phased arrays of modular EMP or High Power Microwave (HPM) sources. ...

    STTR Phase I 2017 Department of DefenseDefense Threat Reduction Agency
  10. Enhanced WAAVES+: A Fast and Accurate Automated USV Scoring Program

    SBC: CORNERSTONE RESEARCH GROUP INC            Topic: DHP16C003

    Cornerstone Research Group (CRG) and the University of Texas (UT) will team to develop a fast and accurate automated analysis program for USV scoring. This automated tool will enable greater research efficiency and throughput allowing greater strides in developing treatments for post-traumatic stress disorder through rodent-based research. Building off prior work by UT on a first generation auto-s ...

    STTR Phase I 2017 Department of DefenseDefense Health Agency
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