Award Data

Traumatic injury accounts for 14.2% of all fatalities. Clinical management of trauma often requires massive plasma transfusions. However, in critical combat casualty care or in civilian emergency trauma care, plasma of compatible blood group may not be readily available. Transfusion with incompatible plasma may result in potentially fatal hemagglutination in the recipient. Typeless or universal pl ...

The Department of Defenseisconcerned about adverseeffects ofcircadian rhythm misalignment on sleep hygiene and well-being ofservice members and veterans who suffer from symptoms of Post-Traumatic Stress Disorder (PTSD). Intelligent Automation, Inc., University of Central Florida RESTORES center and Raytheon IDS, proposeto develop PTSD SleepAid, an end-to-end sleep treatment system that monitors an ...

Thegoal is to develop asoftwaretool that implementsa novelapproach applicableto fitgeneral pharmacologic, toxicology, or other biomedical data, that mayexhibita non-monotonic dose-responserelationship for which thecurrent parametricmodels fail. Thesoftwareexplores dose-responserelationships using both monotonicand non-monotonicmodels,and estimates theassociated doseresponsecurves,which can further ...

Medical moulage is used in medical training to simulate injuries or pathologies, however current moulage is static and does not provide the trainee feedback on the quality of care or ultimate outcome of that care. Allowing a trainee to witness the injury or pathology -morph- while treatment is being provided can provide feedback on any potential mistreatment and enhance the learning and proficienc ...

Ultrasonic vocalizations (USVs) provide an excellent behavioral measure that can be used to understand the effects of traumatic stressors on behavior and can be used to screen and identify therapeutic treatments. This provides a strong justification for the use of rodent USVs as a model for emotional processing in PTSD. Since there are no commercially available USV assessment software programs tha ...

Dose response relationships are fundamental to pharmacology and many other fields. Increasingly, scientists are encountering polytonic dose response relationships. These relationships are not well-characterized by linear and s-shaped models. Our team has extended the traditional 4 parameter logistic model by replacing the dose parameter with the quadratic function as an effective dose function. Th ...

Cornerstone Research Group (CRG) and the University of Texas (UT) will team to develop a fast and accurate automated analysis program for USV scoring. This automated tool will enable greater research efficiency and throughput allowing greater strides in developing treatments for post-traumatic stress disorder through rodent-based research. Building off prior work by UT on a first generation auto-s ...

Biomimetic Slope Adaptive Foot-Ankle Prosthesis This project will develop an innovative mechanical/hydraulic foot-ankle system that will help lower extremity prosthesis wearers to walk or run in a wider range of environments with close to normal walking biomechanics. The proposed system will have a unique combination of features, all mechanically implemented without electronics or external powe ...

Investments by the Department of Defense (DOD) have led to the development and demonstration of electronic textiles capable of transforming traditional textile systems into wearable power and data systems. The Defense Health Agency (DHA) has identified an opportunity to leverage advancements in smart garment systems for military personnel to aid in the prediction in performance declines and healt ...

The Defense Health Program seeks to improve the lives of service members suffering below knee amputations through the development of a non-powered lower extremity prosthesis designed to restore range of motion and power generation to that of an uninjured anatomical ankle. Current passive systems are still in early stages of development and typically only address one aspect of what the Defense Heal ...