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The Award database is continually updated throughout the year. As a result, data for FY21 is not expected to be complete until September, 2022.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Functional Engineering of a Photosynthetic Desalination Pump Circuit

    SBC: Phytodetectors, Inc.            Topic: G

    Phytodetectors will design and engineer a synthetic biological pump circuit to increase the volume of water produced via photosynthetic desalination. This project builds off previous technology designed by Phytodetectors: a mangrove-inspired ultra-filter that allows plants to purify salt water as well as secrete water with properties comparable to bottled water. The partnership seeks to demonstrat ...

    STTR Phase I 2020 Department of EnergyARPA-E
  2. High Power Density Dual Rotor Permanent Magnet Motor with Integrated Cooling and Drive for Aircraft Propulsion

    SBC: Advanced Magnet Lab, Inc.            Topic: 1

    There is a critical need for electrification of transportation systems. The proposed technology enables the development of very high-power density permanent magnet motors, which when coupled to an integrated SiC drive allows for an overall specific power beyond 12 kW/kg. The proposed concept relies on the tight integration of a high-power density dual-rotor permanent magnet motor, high power densi ...

    STTR Phase I 2020 Department of EnergyARPA-E
  3. High Power Density Dual Rotor Permanent Magnet Motor with Integrated Cooling and Drive for Aircraft Propulsion

    SBC: Advanced Magnet Lab, Inc.            Topic: 1

    There is a critical need for electrification of transportation systems. The proposed technology enables the development of very high-power density permanent magnet motors, which when coupled to an integrated SiC drive allows for an overall specific power beyond 12 kW/kg. The proposed concept relies on the tight integration of a high-power density dual-rotor permanent magnet motor, high power densi ...

    STTR Phase II 2020 Department of EnergyARPA-E
  4. High Power Density Dual Rotor Permanent Magnet Motor with Integrated Cooling and Drive for Aircraft Propulsion

    SBC: Advanced Magnet Lab, Inc.            Topic: 1

    There is a critical need for electrification of transportation systems. The proposed technology enables the development of very high-power density permanent magnet motors, which when coupled to an integrated SiC drive allows for an overall specific power beyond 12 kW/kg. The proposed concept relies on the tight integration of a high-power density dual-rotor permanent magnet motor, high power densi ...

    STTR Phase II 2020 Department of EnergyARPA-E
  5. Virtual Reality Tools to Enhance Evidence Based Treatment of Substance Use Disorders (R41/R42- Clinical Trial Optional)

    SBC: BRIGHTLINE INTERACTIVE LLC            Topic: NIDA

    Randamp;R Other Project Information 7. Project Summary/Abstract Neurobiological changes caused by addiction impair behavioral control and increase relapse risk (Volkow, Koob, andamp; McLellan, 2016), substantiating the need for long-term care coordination and recovery engagement for individuals with Substance Use Disorders (SUD) (Humphreys, Malenka, Knutson, andamp; MacCoun, 2017). Because addicti ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  6. Integrated Platform for Mass-Spectrometric Studies of Protein Structure

    SBC: Protein Metrics Inc.            Topic: 400

    Summary Technology for studying the higher order structure (HOS) and interactions of biomolecules is a highlighted NIGMS SBIR/STTR research topic. Mass-spectrometric methods for studying HOS include hydroxyl radical footprinting as well as chemical methods to covalently label amino acid side-chain functional groups, and also hydrogen/deuterium exchange (HDX) on protein backbone amides. These metho ...

    STTR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  7. Pharmacological chaperones for the treatment of Open-Angle Glaucoma

    SBC: Viewpoint Therapeutics, Inc.            Topic: NEI

    Open-angle glaucoma is the second leading cause of blindness worldwide, affecting nearly 70 million individuals. Nonsynonymous mutations in the myocilin gene lead to the most common hereditary form of open-angle glaucoma and account for 3-4% of all cases. Disease-causing mutations, localized to its olfactomedin domain (mOLF), destabilize the myocilin protein, leading to its misfolding and accumula ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  8. Portable, affordable, quantitative microchip electrophoresis system for integrated anemia and hemoglobin variant testing

    SBC: Hemex Health, Inc.            Topic: NHLBI

    PROJECT SUMMARY Anemia is characterized by low blood hemoglobin levels and has high prevalence affecting over one-third of the worldandapos;s population or about 2.5 billion people. Anemia has numerous causes, including nutritional deficiencies, oncologic conditions, and hematologic diseases, including hemoglobin gene variants. More than 7% of the worldandapos;s population carry hemoglobin gene va ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  9. Reversal of Tau Pathology with MSUT2 siRNA Conjugates

    SBC: DTx Pharma, Inc.            Topic: NIA

    Project Summary Genetic and pathologic evidence in andapos;pureandapos; tauopathies such as Progressive Supranuclear Palsy (PSP), Corticobasilar Degeneration (CBD) and some cases of Fronto-temporal Dementia (FTD) directly implicate tau as causing neuronal cell death, while in Alzheimer’s Disease (AD) tau accumulation correlates with development and progression of cognitive impairment. Because of ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  10. A platform for engineering peptide ligase for building next generation peptide therapeutics.

    SBC: Scribe Biosciences, Inc.            Topic: 400

    PROJECT SUMMARY There is an increased interest in peptide medicines in pharmaceutical research and development (Randamp;D) because peptides are recognized as highly selective and efficacious, and at the same time relatively safe and well tolerated. Chemo-enzymatic peptide synthesis (CEPS) using peptide ligases features excellent purity and yield, thus becoming an attractive method to replace tradi ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
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