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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Inspire- In-Mask Sensors for Physiological Investigation of Respiratory Exhalation

    SBC: MAKEL ENGINEERING, INC.            Topic: DHP16C002

    High concentrations of supplemental oxygen are used routinely by pilots and divers prior to and during missions to prevent and treat decompression sickness, avoid detection during covert operations, and to support oxygenation following pulmonary injury. Due to pulmonary oxygen toxicity (PO2T), exposure limits are imposed to prevent damage to pulmonary tissues. Current policy focuses on preventing ...

    STTR Phase II 2021 Department of DefenseDefense Health Agency
  2. Non-invasive Telemetric Assessment of Gut Microbiota Activity in Situ

    SBC: NANOHMICS INC            Topic: DHA17A004

    Different regions of the human GI tract exhibit different chemical environments and different digestion metabolites. As a result, these regions support different microorganisms, with gradients in metabolic products along the length of the GI tract. Single-point measurements of microbiome metabolites (e.g. in feces) are insufficient to provide detailed information of physiological status because th ...

    STTR Phase II 2021 Department of DefenseDefense Health Agency
  3. Oxygen Production on Demand for Military Medical Needs

    SBC: GLOBAL RESEARCH & DEVELOPMENT INC            Topic: DHA17B005

    Topic 17B-005 calls for a new process for supplying medical grade O2 without the use of O2 bottles or pressure (or vacuum) swing absorption (PSA) technology. This is significant to the military for several reasons, because these two sources currently interfere with logistical supply of O2 to where it is required, namely field hospital units. PSA units reportedly have limited shelf life and supply ...

    STTR Phase II 2021 Department of DefenseDefense Health Agency
  4. STTR Phase I: Protease-based purification of recombinant human matrix metalloproteases

    SBC: Sarkar-Klein-Labs            Topic: BT

    The broader impact of this Small Business Technology Transfer (STTR) Phase I project is an enabling technology to improve research into many diseases. This STTR project will develop human matrix metalloprotease (MMPs), a class of enzymes that degrade many biomolecules including collagen, the most abundant structural protein in the human body. MMPs are critical for numerous normal and pathological ...

    STTR Phase I 2021 National Science Foundation
  5. STTR Phase I: A kinetic and conformation based platform for targeting G-protein coupled receptors

    SBC: Seven Biosciences, Inc.            Topic: PT

    The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is to enable the discovery of new therapeutics targeting G protein-coupled receptors (GCPRs). GPCRs are expressed in nearly every organ system, are accessible due to their location on the membrane and potential to elicit almost every signaling pathway. Drugs targeting GPCRs make up 35% of all ...

    STTR Phase I 2021 National Science Foundation
  6. STTR Phase I: A Pair of Linked Cartographic Maps of our Brain Derived from Clinical Glaucoma Data

    SBC: Gautam Thor            Topic: DH

    The broader impact commercial potential of this Small Business Technology Transfer (STTR) Phase I project is to improve the accessibility of eye health care. Glaucoma is a major cause of irreversible blindness but can be addressed with early detection, and the prevalence increases with age. However, existing tests can be tiring and difficult and require specialized equipment. This project will adv ...

    STTR Phase I 2021 National Science Foundation
  7. STTR Phase I: Haptics in Telerobotics for Improved Remote Dexterity

    SBC: TANGIBLE RESEARCH INC.            Topic: R

    The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is to advance haptics - electromechanical systems that operate through the sense of touch. This technology may improve the performance of telemanipulation systems, making the operation similar to that of bare hands, and advance a new generation of robotic tools allowing humans to remotely feel ...

    STTR Phase I 2021 National Science Foundation
  8. STTR Phase I: Microbial Discovery and Biosynthesis of Targeted Protease Inhibitors (COVID-19)

    SBC: THINK BIOSCIENCE, INC.            Topic: PT

    The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase 1 project is to develop new lead compounds for treating COVID-19 by using microbial systems. The microbial assembly approach, which enables rapid, fermentation-based scale-up of therapeutic candidates for pre-clinical studies and early human trials, could accelerate the pace and reduce the cost of thera ...

    STTR Phase I 2021 National Science Foundation
  9. STTR Phase I: Formulation of a COVID-19 mRNA Vaccine by Inverse Flash NanoPrecipitation

    SBC: Optimeos Life Sciences, Inc.            Topic: PT

    The broader impact/commercial potential of this this Small Business Technology Transfer (STTR) Phase I project is the development of a novel messenger ribonucleic acid (mRNA)-based vaccine for COVID-19. The fastest-to-clinic vaccine for COVID-19 was mRNA-based; however, there are no mRNA-based vaccines on the market currently. This is, in part, because this class of vaccines is difficult to optimi ...

    STTR Phase I 2021 National Science Foundation
  10. STTR Phase I: Designer peptide opsonins against COVID-19

    SBC: SAPHTX, INC.            Topic: PT

    The broader impact / commercial potential of this Small Business Technology Transfer (STTR) Phase I project is to develop a new therapeutic for the SARS-CoV-2 virus causing COVID-19. The proposed technology is a novel therapeutic engineered to specifically target the coronavirus and assemble on its surface, disabling the virus’ infectivity. This therapeutic will potentially protect COVID-19 pati ...

    STTR Phase I 2021 National Science Foundation
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