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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Smartphone App to Increase and Maintain Physical Activity in African American Men (FitBrothers)

    SBC: KLEIN BUENDEL, INC.            Topic: 102

    Physical activity (PA) is a modifiable risk factor for a number of preventable chronic diseases, including cardiovascular disease, strokes, obesity, and diabetes. These conditions constitute health disparities for African American men. Behavioral interventions have proven to be effective in promoting increases in physical activity. While behavior change programs have been shown to assist participa ...

    STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  2. Heteroduplex thermostable ligation assembly: a new platform to rapidly generate large DNA molecules

    SBC: Chesapeake Genomic Systems LLC            Topic: 400

    In vitro assembly of DNA fragments andgt;20 kb has recently identified as a critical technical challenge for writing synthetic genomes. Meeting this challenge will increase the efficiency of genome writing projects that depend on large synthetic DNAs, which are iteratively recombined to replace chromosome regions in a step-wise manner to partially or completely re-write bacterial or yeast chromoso ...

    STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  3. Protection of donor kidneys with synchronization modulation electric field (SMEF)

    SBC: WR Biotech, LLC            Topic: 400

    The objective of this proposal is to examine a novel technique called improved Synchronization Modulation Electric Field (i-SMEF) in protection of donor kidneys and improvement of transplanted graft functions. We will apply the i-SMEF on donor kidneys during cold storage and evaluate the transplanted graft function following kidney transplantation in mice.We have developed a novel technique, named ...

    STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  4. Portable hand-held proprietary xenon inhaler for rapid reduction of opioid withdrawal symptoms

    SBC: NOBILIS THERAPEUTICS, INC.            Topic: NIDA

    Summary/Abstract People with opioid use disorder (OUD) experience aversive opioid withdrawal symptoms (OWS) including nausea, diarrhea, vomiting, and anxiety, which emerge when blood opioid levels wane. These symptoms perpetuate unprescribed opioid use and accompanying morbidity and mortality, costing society nearly $80 billion per year. Withdrawal symptoms also emerge upon initiation of OUD pharm ...

    STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  5. I-Corps Project plan for:STTR Phase I Development of therapeutics to treat fentanyl overdose using a validated animal model

    SBC: TORRALVA MEDICAL THERAPUETICS LLC            Topic: NIDA

    Project Summary According to the Centers for Disease Control (CDC), synthetic opioids are currently the most common cause of overdose death in the U.S, while heroin and prescription opioid deaths have decreased significantly since 2017. Despite the widespread availability of naloxone, deaths from fentanyl and fentanyl analogues (F/FA) continue to rise in parallel with increasing reports of F/FA re ...

    STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  6. Multi-Modal Fingertip Sensors for Prosthetic Hand Control and Feedback

    SBC: POINT DESIGNS, LLC            Topic: NIBIB

    Multi-Modal Fingertip Sensors for Prosthetic HandControl and FeedbackPROJECT SUMMARY / ABSTRACT The goal of the proposed project is to develop a robust, multi-modal prosthetic fingertip sensor – the Point Touch – which 1) has a patented multi-modal sensing capability including measurement of proximity, contact, and force and 2) can augment myoelectric control methods using semi-autonomous cont ...

    STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  7. Phospholipid antimetabolite lipid ether amines for topical treatment of chronic wounds and associated biofilms.

    SBC: INTEGUMED LLC            Topic: NIDDK

    ABSTRACT Chronic wounds affect over 2.5 million patients in the US alone, lasting on average 12-13 months and recurring in 60-70% of patients. These occur primarily in lower extremities and vascular disease, diabetes, nephropathy, and metabolic dysfunction are prevalent co-morbidities. These wounds frequently harbor bacterial infections as mixed Gram-negative (e.g. P. aeruginosa, PA) and Gram-posi ...

    STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  8. Use of polymer-peptide system to deliver cells for intervertebral disc regeneration

    SBC: BioRestorative Therapies, Inc.            Topic: NIAMS

    Abstract Low back pain affects millions of Americans and causes $100 billion socioeconomic loss annually. One of the prominent risk factors is intervertebral disc degeneration. Current treatments are palliative for relieving pain without restoring disc biology or biomechanics. Pain recurrence is common. Spinal fusion is popular, but it is limited by high failure rate (up to 30%) while predisposes ...

    STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  9. Chitosan Endoluminal Hemostatic Dressing

    SBC: TRICOL BIOMEDICAL, INC            Topic: 400

    AbstractPost-operative bleeding remains the major complication of transurethral and open prostatic surgical procedures. Prolonged bleeding from these procedures causes delayed healing and longer hospitalization which significantly increases the cost of patient care. Moreover, prolonged urethral catheterization due to significant post-operative hematuria is one of the major causes of discomfort and ...

    STTR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
  10. An augmented reality platform to reduce post-operative and chronic opioid use in pediatric cancer

    SBC: ALTALITY, INC.            Topic: NIDA

    PROJECT SUMMARY/ABSTRACT Pediatric opioid use is a public health crisis. In children, prescription opioids are the primary source of non- medical abuse as well as opioid-associated hospitalizations and deaths. Early opioid use in childhood is a known “gateway” to adulthood dependence and substance abuse disorders. Despite years of research, opioids remain the most commonly prescribed pain medi ...

    STTR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
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