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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Development of Nanvas TM (Oil in Water Nanoemulsion Adjuvant) Formulated Allergens as Intranasal Immunotherapeutic Vaccines for Peanut Allergy

    SBC: BLUEWILLOW BIOLOGICS INC            Topic: NIAID

    Food allergy is an emerging health problem with increasing incidence and severityparticularly in childrenand continuing throughout adulthoodSincethe incidence of self reported peanut allergy has risen significantly representing a mounting financial burden to the healthcare systemWith no approved therapeutics availablevarious forms of immunotherapy have been evaluated but generally do not facilitat ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. TOPIC 386: NOVEL ORALLY BIOAVAILABLE PDE-CATENIN INHIBITOR CONCENTRATES IN LUNG FOR CANCER CHEMOPREVENTION

    SBC: ADT Pharmaceuticals, LLC            Topic: NCI

    This application is based on ADT Pharmaceuticalsdiscoveries thatthe cGMP degrading phosphodiesterase isozymephosphodiesteraseAPDEis overexpressed during early stages of tumorigenesisgenetic knockdown of PDEresults in selective apoptosis of tumor cells by activating cGMP PKG signalingandsmall molecule inhibitors of PDEinduce apoptosis by PKG phosphorylation of oncogeniccateninthereby suppressing Tc ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. TOPIC 389- INTELLIGENT SOFTWARE FOR RADIATION THERAPY PLANNING

    SBC: RADIASOFT LLC            Topic: NCI

    Besides surgeryradiotherapy is the most effective treatment modality for localized prostate cancerThe success of radiotherapy stems from the exploit of a therapeutic window in tumor response and normal tissue tolerance which maximizes the chance of sterilizing the tumor while sparing the surrounding normal tissue from severe damageThis requires an accurate and individualized radiation dose distrib ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Development and evaluation of an all-in-one integrated webbased buprenorphine treatment program for opioid use disorder (Digital Interventions for Opioid Disorders- DIOD)

    SBC: WORKIT HEALTH INC            Topic: NIDA

    Workit Health will develop an automated system that helps clinicians organize and analyze patient dataPatients will express higher rates of treatment adherence in Medication Assisted Treatment in conjunction with psychosocial supportWorkit Health will conduct a randomized clinical trial that combines psychosocial support through CBT modules and peercounselor support and the DIOD program which adds ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Strong protections, tracking, diversion detection, and deactivation of opioid medications in the hospital and related caregiving settings.

    SBC: Curazel LLC            Topic: NIDA

    Under the Small Business Innovation Research ProgramSBIRPhase I programTopicthe Contractor will develop a comprehensive approach to allow hospitals gain control of their opioid medicationsThe Contractor approach is totrack opioids from the pharmacy to the patienttrack the amount given to the patientand for opioid waste to track it back to the pharmacybetter administer opioids to patients that offe ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. STING Inhibitor Discovery for Rare and Common Autoimmune Diseases

    SBC: DISCOVERYBIOMED, INC.            Topic: NIAID

    Principal Investigators for Small BusinessDiscoveryBioMedIncDBMand Nitor TherapeuticsIncNitorProject Summary Abstract The over arching commercial goal for this Nitor TherapeuticsIncNitorand DiscoveryBioMedIncDBMcollaboration is to discover and validate Stimulator of Interferon Genes orSTINGinhibitor ligands in a novel high throughput screeningHTSand validation based Critical Path of bioassaysAberr ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Rodents Derived Synthetic Blood Brain Barrier Models for Chemical Toxicity Screening

    SBC: CFD RESEARCH CORPORATION            Topic: NIEHS

    AbstractThe overall goal of this study is to develop and demonstrate a novelpredictive in vitro organotypicD culture models of the blood brain barrierBBBderived from rodents for chemical toxicity screeningIn contrast with current Transwell based static and microfluidic assaysour commercially available SynBBB model enables real time visualization and quantitation of transport permeation under physi ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Screening Device for Autism Spectrum Disorders using High Stimulation Rate ABR with Continuous Loop Averaging Deconvolution

    SBC: INTELLIGENT HEARING SYSTEMS CORP            Topic: NIDCD

    The purpose of this proposal is to develop an automated Auditory Brainstem ResponseABRbased neurological screening device and software module that will enhance the early detection of autism and other neurological conditionsAutism Spectrum DisordersASDhave an incidence rate ofBased onmillion births in the United States innew cases of ASD will be diagnosed from that birth cohort aloneThe practice of ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Bioinformatic Tools for Interpretation of Glycan Array Data

    SBC: Z BIOTECH, LLC            Topic: 400

    Project SummaryAbstract There is an urgent need of bioinformatic tools for mining glycan array data in order to accurately and statistically study the interactions between cell surface glycans and glycan binding proteinsWe propose here to develop a software and hardware integrated system for the interpretation of glycan array dataThe problem with existing glycan array data mining tools is that the ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. The Effective Parenting Program (EPP): An Integrated Stress Reduction andParenting Intervention for Families of Children with Developmental Disabilities

    SBC: DOUBLE S INSTRUCTIONAL SYSTEMS            Topic: NICHD

    Project Summary!Parents who have children with developmental disabilitiesDDcommonly experience high levels of stress related to child behavior problems and contextual issues related to the childandapos s disability that can have a detrimental effect on their parentingCurrent stress management programs for this population of parents often do not lead to a reduction in childrenandapos s behavior pro ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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