Award Data

Dengue fever and dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS) have emerged as the most important arthropod-borne viral diseases of humans. There are four distinct dengue virus types (DEN-1, DEN-2, DEN-3, and DEN-4), each capable of causingdisease in humans. The conserved 3¿_-noncoding sequences of four dengue virus serotypes have been successfully utilized to develop as a TaqMan-based ...

The objective of this proposal is to demonstrate the feasibility of developing compact 1-10 W fuel cell systems based on the novel, revolutionary, concept of planar microfluidic membraneless fluid cell (PM2FC) recently invented and demonstrated by theauthors of this proposal. The PM2FC concept is closely related to microchannel, membraneless fuel cells (MMC's) that have been previously described ...

72571B03-I Reactive subsurface barriers for groundwater remediation require systems to ensure that the barrier is continuous along its length (without any breaks or holes) and that it continues to remediate the groundwater passing through the barrier. Electrical resistivity measurements made within the barrier wall offer the potential to reliably address these needs in a low-cost manner. This ...

CME proposes a remote unattended sensor platform to detect powered and unpowered watercraft on riverine and inland waterways in South America. CME will define high level and detailed specifications for a sensor and communications platform and evaluatevarious active and passive sensors such as infrared, acoustic, RF, and SONAR that can detect targets across a 500-meter river. We will integrate a se ...

Nanoparticles (NPs) are nanometer-sized metallic compounds that can be coupled to receptors and used as sprays to capture and rapidly detect biowarfare (BW) agents on surfaces. In Phase I, NanoScience Diagnostics (NSD), in conjunction with PaceUniversity, proposes to couple its unique NPs to antibodies and demonstrate detection of E. coli bacteria by a sensitive fluorescence methodology. Since, N ...

Phase I R&D demonstrated feasibility and usefulness of the Pixon-method image reconstruction algorithm for a restricted class of MRFM images. The technical objectives of Phase II research are (1) to optimize data acquisition strategies and reconstructionmethods for general images, (2) to incorporate into the reconstruction regimen provisions for correction of systematic error in specification of t ...

This project will provide a software toolkit to support the development of parallel adaptive numerical analysis codes. This toolkit is primarily focused on computations on unstructured meshes as these types of computations are the most difficult toeffectively parallelize. Building on top of Simmetrix' existing tools and those currently in development, this will result in a complete environment for ...

The objective of the proposed research is to develop a portable, passive system for rapid and efficient blood component separation. While a number of macro-scale devices are routinely employed in laboratory settings to separate, for example, red blood cells (RBCs) from platelet-rich plasma (PRP), and an emerging class of microfabricated devices are slowly being developed to address various low-th ...

Thermopile arrays manufactured using integrated process compatible materials and micro-machining will provide high performance with low manufacturing cost. Black Forest Engineering (BFE) teamed with Case Western Reserve University will design thermopiles using silicon based semiconductors and compare performance. Low cost thermopiles, differentially coupled with advanced BFE CMOS readout, will pr ...

Accurate real-time waterborne pathogen detection is of paramount importance to security of U.S. military forces and installations. Fieldable high-throughput pathogen concentration is a critical analytical need for enhanced detection performance. Existing concentration methods are time-consuming, bulky, labor-intensive, power- and reagent-hungry, and consequently ill-suited for battlefield deployme ...